110 research outputs found

    Dietary supplements in the sport

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    In recent years, the popularity of dietary supplements among athletes has surged, often aimed at enhancing sports performance and improving training outcomes. However, along with this popularity comes an increasing risk of using substances classified as doping in sports. This article examines the current state of knowledge regarding dietary supplements used by athletes, considering the potential risk of violating anti-doping regulations. The article discuss popular ingredients such creatine, beta-alanine, branched-chain amino acids and others

    Factors affecting self-esteem and disease acceptance in patients from infertile couples

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    IntroductionInfertility has been diagnosed in millions of people around the world and is described as a complex medical, mental, and social problem that affects many aspects of life. The aim of the study was to extract the determining factors and the level of self-esteem and the degree of acceptance of the disease in infertile patients and to find differences between women and men in this aspect.MethodsA total 456 patients (235 women and 221 men) from infertile couples participated in a cross-sectional study. To collect data a Personal Information Form (PIF), Rosenberg Self-Esteem Scale (SES), and Acceptance of Illness Scale (AIS) were used.ResultsThe overall self-esteem score for the whole sample was 30.50 (15 ± 30) points and for acceptance of the disease 32.4 (8 ± 40) points. In the study group, men obtained a slightly higher level of self-esteem than women (31.00 vs. 30.04 points). Additionally, men had a higher level of acceptance of the disease (33.12 vs. 31.80) than women. Socio-demographic factors such as age and level of education had impact on scores SES and AIS. Clinical factors did not determine the results of SES and AIS, both in the overall sample and in the female and male groups.ConclusionSelf-esteem in patients from infertile couples increases with age and level of education. There are also significant differences between women and men, i.e., positive correlations between the level of education and self-esteem in men and the degree of acceptance of the disease in women

    Neuroleptic Malignant Syndrome - review of pathophysiology, clinical presentation, differentiation and management

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    Introduction and purpose: The number of invented and produced medications has increased over recent years. Besides their positive impact on health, they invariably provide various kinds of side effects. This review is focused on malignant neuroleptic syndrome, a rare condition with no fully confirmed pathogenesis, which at least partially can be explained as an adverse effect of blocking dopamine receptors. Even though it usually affects psychiatric or neurological patients, doctors of all medical specializations should stay alert, as the condition can often lead to premature death. Brief description of knowledge: The main symptoms associated with NMS are hypertonia, hyperpyrexia, autonomic instability and altered consciousness. They can appear in any configuration, sometimes followed by less characteristic manifestations. It should be primarily differentiated from serotonin syndrome, malignant hyperpyrexia and catatonia, mostly through the interview of those who have taken medications and undergone surgeries, as there are not any specific lab tests available. Fundamental treatment methods consist of neuroleptic withdrawal, intensive supportive care, drug administration and eventually ECT.  Summary: NMS is an uncommon, severe disease that should be carefully considered in patients treated with neuroleptics. Due to its rarity and sudden onset, it appears to be problematic to conduct widespread research and studies, so there are still no concrete, consistent and unquestioned guidelines on recognizing and treating the condition.&nbsp

    Psychedelics as a treatment for patients with post-traumatic stress disorder (PTSD)

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    Introduction and purpose: Post-traumatic stress disorder is a psychiatric condition following an extreme event that causes a near death of an involved individual. Since conventional treatments using selective serotonin reuptake inhibitors do not consistently yield therapeutic success, alternative substances are being explored as potential solutions. This study aims to compile information regarding the outcomes of utilizing psychedelics in individuals diagnosed with PTSD. Brief description of the state of knowledge: In July 2023, after a number of clinical trials and 20-year-long efforts to overturn the impact of a prohibition, Australia became the first country to allow doctors, in clinical development and under strict control, to use the 3,4-methyl​enedioxy​methamphetamine (MDMA) commonly known as ecstasy, as well as psylocybin in patients with post-traumatic stress disorder or depression [8]. There is a noticeable annual growth of inquiries on PubMed involving the keywords "psychedelics" and "therapeutic", amounting to 92 in 2000 and topped by 738 searches in 2023, whereas the total number of results consists of 8415 positions. Therapeutic effects of psychedelics are becoming more recognized over time. Summary: Post-Traumatic Stress Disorder (PTSD) is a complex condition that affects both the psychological and somatic aspects of the body. Thus, a multidimensional intervention is indicated. The use of psychedelics might contribute to improvements not only in the severity of PTSD but also in depression or pain. Further research on a larger group of participants should be carried out to assess the potential role of psychedelics in conventional medicine in the future, alongside psychotherapy

    Deficiency of thiamine and Wernicke-Korsakoff syndrome – review of pathophysiology, clinical presentation , diagnostics and treatment

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    Introduction and aim of the study: Thiamine is a water-soluble vitamine, which bioactive form is necessary for energy metabolism in all cells. Deficiency of thiamine may be caused by malnutrition, alcoholism and certain diseases and it leads to an acute neuropsychiatric disorder called Wernicke encephalopathy. Untreated patients can develop a residual syndrome called Korsakoff syndrome. The aim of our study is to present current knowledge of history, pathophysiology, causes, symptoms and treatment of vitamine B1 depletion and Wernicke-Korsakoff’s syndrome. Material and methods: Our review is based on the analysis of materials collected in „Pubmed”, „Google Scholar” and other scientific articles using keywords: „thiamine”, „thiamine deficiency”, „Wernicke encephalopathy”, „Korsakoff syndrome”. Conclusions: Despite numerous studies, Wernicke encephalopathy is still difficult to diagnose. Attention should be paid to the possibility of vitamin B1 deficiency in people who are at risk of it like alcoholics, malnourished or psychiatric patients. Wernicke encephalopathy is an acute neuropsychiatric disorder so the treatment should be started as soon as possible to reduce the risk of developing Korsakoff syndrome.

    Use of horse riding in chronic pain therapy

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    Introduction and purpose: Chronic pain is a struggle itself and also a symptom in many common conditions. Its complexity requires diverse treatment methods including some that might seem unconventional, for example, horse riding. This study gathers information about the use of equine assisted therapy in pain relief. Brief description of the state of knowledge: Hippotherapy is known as an important part of care for patients with cerebral palsy, attention deficit and autism. The rhythmical, multidimensional movements of the horse are transmitted to the rider’s pelvis and help in strengthening and stretching the muscles which result in better posture stabilization and balance. The positive effects of equine assisted therapy are not limited to only physical ones but positive social, cognitive and psychological effects can be observed as well. In order to lower the cost and time of the therapy, horse riding simulators were invented. So far, horse riding has been tested as a pain relief tool in entities like nonspecific low back pain, multiple sclerosis and arthritis. Summary: Horse riding sessions had beneficial effects on pain levels among patients with nonspecific back pain and arthritis. There is a need to conduct further research in order to properly compare the use of real horses versus horse simulators. Hippotherapy was well perceived by different patient groups so maybe it has the potential to be an important part of pain management in various conditions

    The correlation between diabetes mellitus and depression

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    Depression is the most prevalent mental health condition. It’s estimated that nearly 5% of adults suffer from this disorder globally. Depression is marked by ongoing sadness and a loss of interest or pleasure in activities that were once enjoyable or fulfilling. It can also lead to disruptions in sleep and eating patterns. Common symptoms include fatigue and difficulty concentrating. According to WHO diabetes is a chronic, metabolic disease characterized by elevated levels of blood glucose which leads to the damage of the heart, blood vessels, eyes, kidneys and nerves. Nowadays the occurrence of diabetes mellitus, obesity and depression is getting higher and higher. Both conditions stand as prominent health issues in today’s society. Recent pandemic, wars, problems of the current world can cause depression and anxiety disorders. The fast-paced nature of our lives, work-life balance issues, sedentary habits, and time constraints can lead to opting for fast food and neglecting a healthy diet. People with diabetes are more prone to experiencing depression. Moreover, a significant portion of cases remains underdiagnosed

    Asthma - a healthcare, environment and green transformation - associated disease

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    Air pollution both anthropogenic and from natural sources impacts human health and is a rising problem for healthcare around the world. Key pollutants, such as particulate matter, carbon monoxide, ozone, nitrogen dioxide, and sulphur dioxide, contribute especially to respiratory illnesses. This review examines recent studies in the field of asthma and air pollution correlation, particularly mechanisms of air pollution-related damage, asthma symptoms exacerbations and the risk of developing the disease due to poor air quality. Studies show that pollutants affect the immune system by triggering pro-inflammatory responses and oxidative stress, particularly in individuals with asthma. The review present findings of exacerbation of asthma symptoms and increased frequency of asthma attacks along with higher rates of hospital admissions and emergency room visits due to exposure to common air pollutants. Additionally, prenatal and early-life exposure to traffic-related air pollution proved to significantly increase the risk of developing asthma in children. The review also critically identifies data gaps and methodological inconsistencies in some investigations. The complex relationship between air pollution and asthma is for sure an interesting field to explore furtherly. Analysed materials emphasize the critical need for global measures to reduce air pollution, including stricter air quality regulations and public awareness initiatives
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