Noise Pollution Evaluation in Residential and Residential– Commercial Areas in Tabriz-Iran

Background and Objectives: Over the last three decades environmental pollutions became a more noticeable problem in all around of the world. In many countries, noise pollution as a basic problem has a great importance.Development of the city, increasing of industrial centers, increasing vehicles, other annoying noise resources and also little information about the noise pollution of Tabriz city, has led to the doing of this research.Materials and Methods: Sampling and measuring of noise pressure levels was done 180 times According to the EPA standards, measuring was done simultaneously in two stations(commercial-residential areas), three times a day (morning 7:30 -9:30 am, midday 12:30-14:30 pm and night 19:00-21:00 pm) and 30 days in month.Results: Sound pressure level in both stations was higher than the standards and the highest average level with 71.4 db was recorded in Raste-koche station at midday. Also lowest calculated average value with 68.5 db was measured in Golbad station at the morning time that is 8.5 db higher than the standards. Conclusion: Average measured sound pressure level in two stations was higher than the standards. The results show that Tabriz has a noise pollution in commercial and residential - commercial areas. It is suggested that other noise pollution resources identified and the proper management actions for its reduction be done

Evidences for confirmation of an epidemic in acute respiratory syndrome crisis among residents of Ahwaz November 2013

Background and Objectives: Ahvaz has become one of the most polluted cities in the world. Only on 11 November 2013, over one thousand residents in Khuzestan Province attended the nearest health center with severe symptoms, particularly shortness of breath, cough, wheezing, and high blood pressure. During a week, more than 7 thousand patients were registered with this syndrome. This study was conducted to investigate the evidence for the confirmation of an epidemic in acute respiratory syndrome among the residents of Ahwaz in November 2013. Methods: In this cross-sectional study, we evaluated the data of the use of drugs related to acute respiratory attacks from November 2008 to 2013 in Ahvaz. Then, we conducted a descriptive study on the general population. The sample size was 120 and the study participants included different segments of the general population. The data collection tool was a researcher-made questionnaire and the data were analyzed using SPSS.18. Results: The use of the respiratory drugs increased from 2008 to 2013. The drug consumption was markedly higher in November 2013. In the study of the general population, 93 of the participants declared that they had never seen a similar event, and 92.5 mentioned that they had never heard of a similar occurrence. Conclusion: Due to the significant increase in respiratory medicine in November 2013 and the unexpected nature of the event, an epidemic seems to be obvious. © 2016, Iranian Epidemiological Association. All rights reserved

A third vaccination with a single T cell epitope confers protection in a murine model of SARS-CoV-2 infection

Understanding the mechanisms and impact of booster vaccinations are essential in the design and delivery of vaccination programs. Here we show that a three dose regimen of a synthetic peptide vaccine elicits an accruing CD8+ T cell response against one SARS-CoV-2 Spike epitope. We see protection against lethal SARS-CoV-2 infection in the K18-hACE2 transgenic mouse model in the absence of neutralizing antibodies, but two dose approaches are insufficient to confer protection. The third vaccine dose of the single T cell epitope peptide results in superior generation of effector-memory T cells and tissue-resident memory T cells, and these tertiary vaccine-specific CD8+ T cells are characterized by enhanced polyfunctional cytokine production. Moreover, fate mapping shows that a substantial fraction of the tertiary CD8+ effector-memory T cells develop from re-migrated tissue-resident memory T cells. Thus, repeated booster vaccinations quantitatively and qualitatively improve the CD8+ T cell response leading to protection against otherwise lethal SARS-CoV-2 infection