DOI: 10.2298/AOO0602057V Nasal glioma

Congenital midline nasal masses are rather rare anomalies that occur in about one in 20 000- 40 000 live births. Nasal gliomas account for approximately 5 % of all congenital nasal swellings. The most common are dermoid/epidermoid tumors, nasal cerebral heterotopias (nasal gliomas), and nasal encephaloceles, with clinical significance that some of them have an actual or potential central nervous system connection. We present a case of an 8-year-old boy who complained of slight hearing loss dating 2 month before. Anterior rhinoscopy showed an oval, elastic, smooth, uncompressible mass, at the upper third of the nasal septum, unchanged in size on the Valsalva test. The mass causes breathing difficulties on that left naris. Clinical diagnosis was hemangioma. In the histopathologic laboratory, on gross examination, the mass measured 1.0 x 0.7 x 0.5 cm, was well demarcated, smooth, elastic, homogeneous, firm and whitish-gray in color. On cut section, the mass was homogenous, firm whitish gray in color. It consisted of astrocytic neuroglial cells with fibrous connective tissue and covered by the normal respiratory mucosa. The diagnosis of a nasal glioma was made

Original article UDC: 616-006:613.84:616-037 Archive of Oncology 2002;10(2):67-70.

Cigarette smoking as a risk factor associated with oral leukoplaki

Presence of Candida albicans in potentially malignant oral mucosal lesions

Recently, an interest in the study of oral candidiasis has markedly increased mainly because of its association with viral infections due to human immunodeficiency, but also because of its relation with potentially malignant lesions of oral mucosa. These lesions belong to the wide group of leukoplakia. Leukoplakia is a clinical term used to describe a range of nonspecific white lesions, whose appearance does not generally correlate well with histopathologic changes; therefore, biopsy should be performed in all cases to determine which are precancerous or potentially malignant ones. In order to study the association of Candida albicans and the types of mucosal lesions, we took 30 consecutive biopsies of oral mucosa and the smears for microbiologic examination from the changed surface of mucosa and from the rest of oral cavity. The study group consisted of 30 patients, 21 women and 9 men, with the average age of 50.23 years (range, 25-77 years). In 6 cases Candida was diagnosed in mucosal biopsy. In the smear from the lesion, it was present in 3 cases, and 2 cases were found in the smear from an unchanged oral mucosa. In 9/30 cases (30%) Candida was positive regardless of the smear area or mode of diagnosis. The most common lesion is leukoplakia, diagnosed in 12/30 cases (40%), in 6 female and 6 male patients. The average age of those patients was 52.42 years. The lesions were located as follows: cheek mucosa- 5 cases; gingiva

Original article UDC: 616.988.6:616-006.4:616-089.8 Archive of Oncology 2003;11(1):9-11. The problem of local recurrence and metastasis in soft-tissue sarcoma

BACKGROUND: The purpose of this study was to evaluate local recurrence of soft-tissue sarcomas as a prognostic factor reflecting adequate or inadequate excision. METHODS: We reviewed the cases of 53 patients who had soft-tissue sarcomas and were treated between 1991 and 2001. All patients were treated operatively, but 11 of them (20.75%), before being sent to us, were operated elsewhere with inadequate surgical margins. The oncology status, including local recurrence and metastasis was determined at the follow-up evaluation. RESULTS: All of 11 patients treated with inadequate excision had palpably or histologically determined local recurrence. The most common histological diagnosis of local recurrence was dermatofibroma protuberans (7 patients, 63.63%). In patients who were treated with planned and adequate excision there were 4 (9.52%) recurrences. Five patients (45.45%) had metastases in the group of inadequate and only one patient (1.88%) in the group of adequate surgical margins. CONCLUSION: Our study demonstrated that excellent rates of survival and low rates of local recurrence and distant metastasis of soft-tissue sarcomas could be obtained with the use of carefully planned radical resection. The quality of operation is the most important factor

Case report UDC: 616.428:616.071:616-053.2 Archive of Oncology 2004;12(1):75-7.

Pigmented villonodular synovitis of the knee in a child- case repor

fatal

Lobular panniculitis: A manifestation of pancreatic tumor wit