Pronostic vital et fonctionnel de l'ischémie critique chez les octogénaires pris en charge en chirurgie vasculaire

STRASBOURG-Medecine (674822101) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Intérêts et bénéfices de la chirurgie de revascularisation carotidienne chez l'octogénaire.

STRASBOURG-Medecine (674822101) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Les endofuites après traitement endovasculaire des anévrysmes de l'aorte abdominale sous rénale

STRASBOURG-Medecine (674822101) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Hybrid textile heart valve prosthesis : preliminary in vitro evaluation

International audienceTranscatheter aortic valve implantation (TAVI) is nowadays a popular alternative technique to surgical valve replacement for critical patients. Biological valve tissue has been used in these devices for over a decade now with over 100,000 implantations. However, material degradations due to crimping for catheter insertion purpose have been reported, and with only 6-year follow-up, no information is available about the long-term durability of biological tis-sue. Moreover, expensive biological tissue harvesting and chemical treatment procedures tend to promote the devel-opment of synthetic valve leaflet materials. Textile polyes-ter (PET) material is characterized by outstanding folding and strength properties combined with proven biocompat-ibility and could therefore be considered as a candidate to replace biological valve leaflets in TAVI devices. Neverthe-less, the material should be preferentially partly elastic in order to limit water hammer effects at valve closing time and prevent exaggerated stress from occurring into the stent and the valve. The purpose of the present work is to study in vitro the mechanical as well as the hydrodynamic behavior of a hybrid elastic textile valve device combining non-deformable PET yarn and elastic polyurethane (PU) yarn. The hybrid valve properties are compared with those of a non-elastic textile valve. Testing results show improved hydrodynamic properties with the elastic construction. However, under fatigue conditions, the interaction between PU and PET yarns tends to limit the valve durability