16 research outputs found
Challenges for nursing education in Angola: the perception of nurse leaders affiliated with professional education institutions
Vaccination against pneumococcus in West Africa: perspectives and prospects
Eric S Donkor,1 Nicholas TKD Dayie,1,2 Ebenezer V Badoe3 1Department of Microbiology, University of Ghana Medical School, Accra, Ghana; 2Department of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; 3Department of Child Health, University of Ghana Medical School, Accra, Ghana Background: Pneumococcal vaccination has become obligatory due to the enormous burden of pneumococcal diseases. Quite recently, pneumococcal conjugate vaccines have been developed, and have been shown to be superior to the previous polyvalent polysaccharide vaccine of the organism. Pneumococcal conjugate vaccines (PCVs) are being introduced in many West African countries and it is important to understand the expected performance, relevance, and limitations of these vaccines in the subregion. Aim: The objective of the study presented here was to provide epidemiological insights into PCVs in West Africa based on the prevailing pneumococcal serotypes in the subregion. Methods: A systematic review was carried out on pneumococcal serotypes causing invasive and noninvasive diseases in West Africa. Studies included in the review were those that reported at least 20 serotyped pneumococcal isolates and which were conducted prior to the introduction of PCVs in the region in 2009. The proportion of pneumococcal disease associated with each serotype as well as the serotype coverage of various PCVs (PCV7, PCV10, and PCV13) were calculated. Results: The data covered 718 serotyped pneumococcal isolates from six West African countries: Burkina Faso, Ghana, Nigeria, Mali, Senegal, and The Gambia. The 718 isolates covered more than 20 serotypes. Serotype 1 was the most prevalent serotype (32%), followed by serotype 5 (15%), serotype 6 (7%), serotype 2 (6%), serotype 3 (6%), and serotype 12 (5%). The estimated serotype coverage of PCVs among the West African countries was 2%–36% for PCV7, 39%–80% for PCV10, and 65%–87% for PCV13. Conclusion: A pneumococcal capsular vaccine for use in West Africa must contain serotypes 1 and 5, the most important serotypes responsible for pneumococcal disease in the region. Consequently, while PCV10 and PCV13 are generally suitable for use in West Africa, PCV7 is unsuitable. Keywords: pneumococcus, conjugate vaccines, serotype, PVC10, PVC13, pneumococcal disease, Streptococcus pneumonia
Nurses’ knowledge in ethics and their perceptions regarding continuing ethics education: a cross-sectional survey among nurses at three referral hospitals in Uganda
Long-term impacts of season of grazing on soil carbon sequestration and selected soil properties in the arid Eastern Cape, South Africa
BACKGROUND AND AIMS : The karoo biomes of South Africa are major feed resources, yet soil nutrient depletion
and degradation is a major problem. The objective of this study was to assess impacts of long-term (>75 years)
grazing during spring (SPG), summer (SUG), winter (WG) and exclosure (non-grazed control) treatments on
soil nutrients, penetration resistance and infiltration tests.
METHODS : A soil sampling campaign was carried out to collect soil to a depth of 60 cm to analyse bulk density,
soil physical and chemical parameters as well as soil compaction and infiltration.
RESULTS : Generally, grazing treatments reduced soil organic C (SOC) stocks and C:N ratios, and modified soil
properties. There was higher SOC stock (0.128 Mg ha-1 yr-1) in the exclosure than in the SPG (0.096 Mg ha-1 yr-
1), SUG (0.099 Mg ha-1 yr-1) and WG (0.105 Mg ha-1 yr-1). The C:N ratios exhibited similar pattern to that of C.
From the grazing treatments, the WG demonstrated 7 to 10% additional SOC stock over the SPG and SUG,
respectively.
CONCLUSIONS : Short period animal exclusion could be an option to be considered to improve plant nutrients in
sandy soils of South Africa. However, this may require a policy environment which supports stock exclusion
from such areas vulnerable to land degradation, nutrient and C losses by grazing-induced vegetation and
landscape changes.Department of Science and Technology University of Pretoria) and the European Communities, 7th framework program under the grant agreement No.
266018, ANIMALCHANGE project.http://link.springer.com/journal/111042016-12-31hb201