1 research outputs found
Antimikrobno djelovanje nekih glukopiranozil-pirimidin karbonitrila i fuzioniranih pirimidinskih sustava
3-Amino-5-(4-chlorophenylamino)-4-cyanofuran-2-carboxamide (2) was used as the key molecule for preparation of various furo- pyrimidines 3-9 and formation of spiro-cycloalkane furopyrimidines 10, 11. Also, poly fused heterocyclic compounds 13-17 were prepared from compound 2. The synthesized compounds were screened for their antimicrobial activity.3-Amino-5-(4-klorfenilamino)-4-cijanofuran-2-karboksamid (2) upotrebljen je kao kljuÄni spoj za pripravu razliÄitih furo-pirimidina 3-9 i spiro-cikloalkane furopirimidina 10 i 11. Fuzionirani heterocikliÄki spojevi 13-17 pripravljeni su takoÄer polazeÄi iz spoja 2. Sintetizirani spojevi ispitani su na antimikrobno djelovanje