654 research outputs found

    Algebraic Structure in 0<c<1 Open-Closed String Field Theories

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    We apply stochastic quantization method to Kostov's matrix-vector models for the second quantization of orientable strings with Chan-Paton like factors, including both open and closed strings. The Fokker-Planck hamiltonian deduces an orientable open-closed string field theory at the double scaling limit. There appears an algebraic structure in the continuum F-P hamiltonian including a Virasoro algebra and a SU(r) current algebra.Comment: LaTeX 9 page

    Low levels of plasma endothelin-1 in patients with retinitis pigmentosa

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    Hiroshi Ohguro1, Yukihiko Mashima2, Mitsuru Nakazawa31Department of Ophthalmology, Sapporo Medical University School of Medicine, 2Department of Ophthalmology, Keio University School of Medicine, 3Department of Ophthalmology, Hirosaki University School of Medicine, JapanPurpose: The aim of this study was to elucidate the role of endothelin-1 (ET-1) in the pathophysiology of retinitis pigmentosa (RP).Methods: Plasma ET-1 levels and ophthalmic features in 50 RP patients were compared with those in 20 healthy-eye control subjects. Plasma ET-1 concentrations were determined using a commercially available enzyme-linked immunosorbent assay kit.Results: Mean plasma ET-1 levels of RP patients (1.88 &amp;plusmn; 0.56 pg/mL) were significantly lower than those of control subjects (2.30 &amp;plusmn; 0.30 pg/mL, Mann-Whitney&amp;rsquo;s U test; P &amp;lt; 0.01). However, ET-1 concentrations varied markedly in each patient. Among RP patients, a significant correlation of ET-1 concentrations was not observed in terms of its hereditary forms or other clinical factors.Conclusion: ET-1 may be important in the pathogenesis of RP, and measurement of its plasma concentrations may also contribute to additional insights into the retinal hemodynamics of RP.Keywords: endothelin-1, retinitis pigmentosa, retinal hemodynamic

    Carbon­yl(η5-cyclo­penta­dien­yl)(pyridine)(triethyl­stann­yl)iron(II)

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    In the title complex, [Fe(C5H5){Sn(C2H5)3}(C5H5N)(CO)], the Fe atom is coordinated by carbonyl, pyridine, triethyl­stannyl and cyclo­penta­dienyl ligands in a typical three-legged piano-stool configuration. The Fe—Sn and Fe—N bond distances are 2.5455 (13) and 1.984 (6) Å, respectively

    On the Seismic Earth Pressure Reduction Against Retaining Structures Using Lightweight Geofoam Fill

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    A numerical analysis was carried out for a rigid retaining wall experiencing earthquake loading. The seismic forces acting on the wall was determined by simulating both sinusoidal load as well as the earthquake time history of an actual earthquake. At first considering that the backfill consists purely of sandy soils, the failure zone and the resulting earth pressure were calculated. After observing the failure zone of such backfill, the domain is substituted by lightweight Expanded Polystyrene (EPS) geofoam. The effect of replacing the sand with such lightweight materials on the developed seismic thrust is then examined. The results show that the use of the EPS geofoam as a replacement renders as much as 50% to 60% reduction of the seismic thrust

    Successful Removal of Large Intraocular Foreign Body by 25-Gauge Microincision Vitrectomy Surgery

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    We describe a new technique for removing a large intraocular foreign body by 25-gauge microincision vitrectomy surgery (25G-MIVS). Noncomparative interventional case series were performed at a single centre. Two patients with a long smooth intraocular vitreal foreign body underwent phacoemulsification and aspiration, intraocular lens implantation, 25G-MIVS, and extraction of the foreign body. The foreign body was removed through a posterior capsulorhexis, anterior continuous curvilinear capsulorhexis, and a corneal incision. In both cases, the foreign body was safely removed through the corneal incision, and IOL was implanted and well positioned. The surgical incision did not require suturing. No postoperative complications associated with this technique were found. The corneal endothelial cell density was maintained over 2000 cells/mm2 in both cases during recent follow-up examinations. Our findings indicate that 25G-MIVS with this technique can be used to extract a long slender smooth foreign body. It is safe, without complications, and can be performed without enlarging the 25-gauge sclerotomy

    Prolonged survival of the phosphorylated form of rhodopsin during dark adaptation of Royal College Surgeons rat

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    AbstractTo study rhodopsin (Rho) phosphorylation and dephosphorylation in Royal College of Surgeons (RCS) rat retina, specific antibodies toward major Rho phosphorylation sites in vivo, 334Ser or 338Ser, were prepared by immunization of authentic phosphorylated peptides in rabbit. Enzyme-linked immunosorbent assay identified that the raised antibodies exclusively recognized either the phosphorylated 334Ser or 338Ser site. In immunofluorescence labeling, both antibodies recognized photoreceptor outer segments in light-adapted retinas from Sprague–Dawley (SD), Brown–Norway (BN) and RCS rat. During dark adaptation, immunoreactivities toward phosphorylated 338Ser and 334Ser sites were diminished within several hours (0.2–2 h) in SD and BN rat retinas. However, those toward phosphorylated 338Ser and 334Ser sites were diminished within 4 to 7 days in RCS rat retinas. In vitro studies demonstrated decreased levels of both Rho phosphorylation and dephosphorylation reactions in RCS retinas. However, the dephosphorylation reaction was much more greatly affected than the phosphorylation reaction. Extremely prolonged survival of phosphorylated forms of Rho may contribute to persistent misregulation of phototransduction processes in retinal degeneration in RCS rat
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