160 research outputs found

    The germination of nationalism in lower class from the late 19th century: as the prehistory of mine rights recovery movement in Shanxi

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    The coal resources of Shanxi Province play a significant role not only in Shanxi but also in the development of Chinese modern industry. The mine rights recovery movement in Shanxi is an important event. There are many relative researches, but mainly focus on the role of capitalists and student-centered intellectuals, the activities of lower classes who occupied a large number in the society at that time were simply explained that they were incited by upper classes. This paper focuses on lower classes and aims to figure out how their nationalism was awakened by the great change of society because of foreign aggression. Also, lower classes’ efforts will be analyzed in order to proof the existence of nationalism

    3D Particle Simulation of Liver Cell Proliferation with Angiogenesis - Partial Hepatic Lobule Formation-

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    Recently, the prevalence of viral hepatitis patients has been increasing. Therefore, the reconstruction of liver based on tissue engineering has attracted significant attention. However, the formation or regeneration mechanisms of the liver have not been elucidated; therefore, practical regenerative medicine technology based on tissue engineered liver has not been accomplished. In this study, we propose an analysis model using a Particle Model as the first step. The analysis object is a hepatic lobule. The purpose of this analysis is to elucidate the process of cell proliferation, mechanisms, and states at the micro scale. We used parameters which were obtained by experiments using rats relating to diffusivity, oxygen concentration, and oxygen consumption of a cell. Moreover, we used complex velocity potential of fluid dynamics and obtained a result corresponding to a real hepatic lobule, qualitatively.The 6th TSME International Conference on Mechanical Engineering, 16-18 December 2015, at The Regent Cha-am beach Resort, Hua-Hin, Thailand

    3D Numerical Simulation of Hair Formation Process Using a Particle Model

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    Hair is very important in determining human appearance. Although there are numerous observed data and experimental recordings for hair, a detailed mechanism of hair formation has not yet been elucidated. Therefore, in this study, a simulation of the method of formative process of hair roots was done using a 3D particle model. The model contains details of the cell growth from the hair matrix cells and changes from spherical to non-spherical oval shape. Simulation results were able to exhibit the hair formation process from the base of the hair follicle. Furthermore, at the surface opening of the follicle, the hair structure was recorded. Therefore, this model can be used to clarify the mechanism of hair root formation

    3D Particle Simulation of Liver Cell Proliferation with Angiogenesis - Partial Hepatic Lobule Formation-

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    The 6th TSME International Conference on Mechanical Engineering, 16-18 December 2015, at The Regent Cha-am beach Resort, Hua-Hin, Thailand.Recently, the prevalence of viral hepatitis patients has been increasing. Therefore, the reconstruction of liver based on tissue engineering has attracted significant attention. However, the formation or regeneration mechanisms of the liver have not been elucidated; therefore, practical regenerative medicine technology based on tissue engineered liver has not been accomplished. In this study, we propose an analysis model using a Particle Model as the first step. The analysis object is a hepatic lobule. The purpose of this analysis is to elucidate the process of cell proliferation, mechanisms, and states at the micro scale. We used parameters which were obtained by experiments using rats relating to diffusivity, oxygen concentration, and oxygen consumption of a cell. Moreover, we used complex velocity potential of fluid dynamics and obtained a result corresponding to a real hepatic lobule, qualitatively

    2D Particle Simulation of Liver Cell Proliferation with Angiogenesis - Hepatic Lobule Formation

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    The liver has the ability to reform and regenerate in our body. However, the mechanisms of reformation or regeneration of the liver have not been elucidated. In this study, we propose an analysis model using a Particle Model to elucidate the mechanism of liver formation. The object of analysis is a hepatic lobule, which is the basic component of the liver. First, a 2-dimensional cell proliferation around one blood vessel was modeled. Second, angiogenesis was added and considered. And finally, the model was applied to the hepatic lobule and the 2D formation of the hepatic lobule was revealed. We used experimentally derived parameters such as diffusivity, oxygen concentration, and oxygen consumption of a cell. The model will be expected to facilitate in developing tissue-engineered liver using regenerative medicine technology.2nd Conference on Advances in Prevention and Treatment of Cancer (CAPTC 2016), March 18-20, 2016, Los Angeles, US

    Two floating camphor particles interacting through lateral capillary force

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    We consider a mathematical model for a two-particle system driven by the spatial gradient of a concentration field of chemicals with conservative attractive interactions in one dimension. This setup corresponds to an experimental system with floating camphor particles at a water surface. Repulsive interaction is introduced, as well as self-propelling force, through the concentration field of camphor molecules at the water surface. Here we newly adopt the attractive lateral capillary force due to the deformation of the water surface. The particles experience competing dissipative repulsion and conservative attraction. We numerically investigated the mathematical model, and found six different modes of motion. The theoretical approach revealed that some of such mode transitions can be understood in terms of bifurcation.Comment: 9 pages, 6 figure

    Particle Simulation of Liver Cell Proliferation with Angiogenesis -Whole Hepatic Lobule Formation-

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    The liver is the organ primarily responsible for our metabolism and loss of its function generally results in death. Luckily, the liver has a high regenerative ability. However, the mechanism of its regeneration has not yet been clarified. This study therefore models liver regeneration via a numerical simulation. In addition, this simulation may aid other experiments in the field of regenerative medicine. As a first step, this study proposes an analytical model based on the particle method. The analysis object is a hepatic lobule. The purpose of this analysis is to elucidate the process, mechanism, and condition of cell growth on the micro-scale. Experiments using rats were conducted to obtain the parameters for the model, namely the diffusivity, oxygen concentration, and oxygen consumption rate of a cell. The most difficult to solve problem in liver cell proliferation technology is the restricted volume in which cells survive owing to oxygen supply problems. It is therefore necessary to extend the cell survival volume by angiogenesis. Here, results were generated using a model of angiogenesis in which blood vessels formed from the portal veins to a central vein, with repeated branching and connecting across the whole of the liver. In this way a hepatic lobule was filled with liver cells. Additionally, the analysis results yielded the rates of the cross sectional areas of the blood vessels. This research further aims to analyze the macro region by using analysis results obtained on the micro-scale. Applying the thresholds which is the most closed to the experimental value obtained from analysis results on the micro-scale to the macro region, it becomes available to curtail expenses and be kind to animals in the liver experiments.The 7th International Conference on Mechanical Engineering (TSME-ICoME 2016), 13-16 December 2016, Chiang Mai, Thailand

    Chemo-Sensitive Running Droplet

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    Chemical control of the spontaneous motion of a reactive oil droplet moving on a glass substrate under an aqueous phase is reported. Experimental results show that the self-motion of an oil droplet is confined on an acid-treated glass surface. The transient behavior of oil-droplet motion is also observed with a high-speed video camera. A mathematical model that incorporates the effect of the glass surface charge is built based on the experimental observation of oil-droplet motion. A numerical simulation of this mathematical model reproduced the essential features concerning confinement within a certain chemical territory of oil-droplet motion, and also its transient behavior. Our results may shed light on physical aspects of reactive spreading and a chemotaxis in living things.Comment: 17 pages, 10 figure
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