Utilização da plataforma Galaxy na análise de dados de RNAseq.

Este trabalho teve como objetivo avaliar a plataforma Galaxy na análise de dados de RNA-seq, uma metodologia de sequenciamento de transcritos (moléculas de RNAm) que utiliza as novas tecnologias de sequenciamento (NTS)

Model-independent X-ray mass determinations

A new method is introduced for making X-ray mass determinations of spherical clusters of galaxies. Treating the distribution of gravitating matter as piecewise constant and the cluster atmosphere as piecewise isothermal, X-ray spectra of a hydrostatic atmosphere are determined up to a single overall normalizing factor. In contrast to more conventional approaches, this method relies on the minimum of assumptions, apart from the conditions of hydrostatic equilibrium and spherical symmetry. The method has been implemented as an XSPEC mixing model called CLMASS, which was used to determine masses for a sample of nine relaxed X-ray clusters. Compared to conventional mass determinations, CLMASS provides weak constraints on values of M_500, reflecting the quality of current X-ray data for cluster regions beyond r_500. At smaller radii, where there are high quality X-ray spectra inside and outside the radius of interest to constrain the mass, CLMASS gives confidence ranges for M_2500 that are only moderately less restrictive than those from more familiar mass determination methods. The CLMASS model provides some advantages over other methods and should prove useful for mass determinations in regions where there are high quality X-ray data.Comment: 12 pages, 8 figures, accepted for publication in Ap

The one-dimensional Keller-Segel model with fractional diffusion of cells

We investigate the one-dimensional Keller-Segel model where the diffusion is replaced by a non-local operator, namely the fractional diffusion with exponent $0<\alpha\leq 2$. We prove some features related to the classical two-dimensional Keller-Segel system: blow-up may or may not occur depending on the initial data. More precisely a singularity appears in finite time when $\alpha<1$ and the initial configuration of cells is sufficiently concentrated. On the opposite, global existence holds true for $\alpha\leq1$ if the initial density is small enough in the sense of the $L^{1/\alpha}$ norm.Comment: 12 page

Chemotactic Collapse and Mesenchymal Morphogenesis

We study the effect of chemotactic signaling among mesenchymal cells. We show that the particular physiology of the mesenchymal cells allows one-dimensional collapse in contrast to the case of bacteria, and that the mesenchymal morphogenesis represents thus a more complex type of pattern formation than those found in bacterial colonies. We finally compare our theoretical predictions with recent in vitro experiments

Preliminary analysis of differentially expressed genes involved in meat tenderness in Angus and Nelore beef cattle.

ISCB-Latin America 2014. Pôster O10

Cosmology with X-ray Cluster Baryons

X-ray cluster measurements interpreted with a universal baryon/gas mass fraction can theoretically serve as a cosmological distance probe. We examine issues of cosmological sensitivity for current (e.g. Chandra X-ray Observatory, XMM-Newton) and next generation (e.g. Con-X, XEUS) observations, along with systematic uncertainties and biases. To give competitive next generation constraints on dark energy, we find that systematics will need to be controlled to better than 1% and any evolution in f_gas (and other cluster gas properties) must be calibrated so the residual uncertainty is weaker than (1+z)^{0.03}.Comment: 6 pages, 5 figures; v2: 13 pages, substantial elaboration and reordering, matches JCAP versio

On War: The Dynamics of Vicious Civilizations

The dynamics of ``vicious'', continuously growing civilizations (domains), which engage in ``war'' whenever two domains meet, is investigated. In the war event, the smaller domain is annihilated, while the larger domain is reduced in size by a fraction \e of the casualties of the loser. Here \e quantifies the fairness of the war, with \e=1 corresponding to a fair war with equal casualties on both side, and \e=0 corresponding to a completely unfair war where the winner suffers no casualties. In the heterogeneous version of the model, evolution begins from a specified initial distribution of domains, while in the homogeneous system, there is a continuous and spatially uniform input of point domains, in addition to the growth and warfare. For the heterogeneous case, the rate equations are derived and solved, and comparisons with numerical simulations are made. An exact solution is also derived for the case of equal size domains in one dimension. The heterogeneous system is found to coarsen, with the typical cluster size growing linearly in time $t$ and the number density of domains decreases as $1/t$. For the homogeneous system, two different long-time behaviors arise as a function of \e. When 1/2<\e\leq 1 (relatively fair wars), a steady state arises which is characterized by egalitarian competition between domains of comparable size. In the limiting case of \e=1, rate equations which simultaneously account for the distribution of domains and that of the intervening gaps are derived and solved. The steady state is characterized by domains whose age is typically much larger than their size. When 0\leq\e<1/2 (unfair wars), a few ``superpowers'' ultimately dominate. Simulations indicate that this coarsening process is characterized by power-law temporal behavior, with non-universalComment: 43 pages, plain TeX, 12 figures included, gzipped and uuencode

Turbulence in Clusters of Galaxies and X-Ray Line Profiles

Large-scale bulk motions and hydrodynamic turbulence in the intergalactic gas inside clusters of galaxies significantly broaden X-ray emission lines. For lines of heavy ions (primarily helium-like and hydrogen-like iron ions), the hydrodynamic broadening is significantly larger than the thermal broadening. Since cluster of galaxies have a negligible optical depth for resonant scattering in forbidden and intercombination lines of these ions, these lines are not additionally broadened. At the same time, they are very intense, which allows deviations of the spectrum from the Gaussian spectrum in the line wings to be investigated. The line shape becomes an important indicator of bulk hydrodynamic processes because the cryogenic detectors of new generation of X-ray observatories will have a high energy resolution (from 5 eV for ASTRO-E2 to 1-2 eV for Constellation-X and XEUS). We use the spectral representation of a Kolmogorov cascade in the inertial range to calculate the characteristic shapes of X-ray lines. Significant deviations in the line profiles from the Gaussian profile (shape asymmetry, additional peaks, sharp breaks in the exponential tails) are expected for large-scale turbulence. The kinematic SZ effect and the X-ray line profile carry different information about the hydrodynamic velocity distribution in clusters of galaxies and complement each other, allowing the redshift, the peculiar velocity of the cluster, and the bulk velocity dispersion to be measured and separatedComment: 29 pages, 12 figures, Astronomy Letters 2003, v.29, p.79