Non-Markovian decoherence of a two-level system in a Lorentzian bosonic reservoir and a stochastic environment with finite correlation time

In this paper we investigate non-Markovian evolution of a two-level system (qubit) in a bosonic bath under influence of an external classical fluctuating environment. The interaction with the bath has the Lorentzian spectral density, and the fluctuating environment (stochastic field) is represented by a set of Ornstein-Uhlenbeck processes. Each of the subenvironments of the composite environment is able to induce non-Markovian dynamics of the two-level system. By means of the numerically exact method of hierarchical equations of motion, we study steady states of the two-level system, evolution of the reduced density matrix and the equilibrium emission spectra in dependence on the frequency cutoffs and the coupling strengths of the subenvironments. Additionally, we investigate the impact of the rotating wave approximation (RWA) for the interaction with the bath on accuracy of the results

BPS Electromagnetic Waves on Giant Gravitons

We find new 1/8-BPS giant graviton solutions in $AdS_5 \times S^5$, carrying three angular momenta along $S^5$, and investigate their properties. Especially, we show that nonzero worldvolume gauge fields are admitted preserving supersymmetry. These gauge field modes can be viewed as electromagnetic waves along the compact D3 brane, whose Poynting vector contributes to the BPS angular momenta. We also analyze the (nearly-)spherical giant gravitons with worldvolume gauge fields in detail. Expressing the $S^3$ in Hopf fibration ($S^1$ fibred over $S^2$), the wave propagates along the $S^1$ fiber.Comment: 25 pages, no figures, v2: references adde

Development of gradient diffusion strips to identify the potentiating effect of antimicrobial compounds against multidrug-resistant Klebsiella pneumoniae strains

Objective. The aim of the study was to develop gradient diffusion strips with substances capable of potentiating the action of antibiotics for the treatment of infections caused by multidrug-resistant strains of K. pneumoniae. Materials and Methods. The substances azidothymidine and baicalin were used to evaluate the joint action of combinations of antibiotics with substances that potentiate their action. Determination of susceptibility to combinations of antibiotics (gentamicin, cefotaxime, ciprofloxacin and chloramphenicol) with the listed substances was carried out by a modified gradient-diffusion method (cross-test). We used gradient diffusion strips, which was made in the Saint-Petersburg Pasteur Institute. We investigated clinical multidrug-resistant K. pneumoniae strains (n = 20). The result of the joint action of a combination of two compounds was assessed by calculating the fractional inhibitory concentrations ΣFIC. Results. The values of MIC decreased eightfold when azidothymidine was combined with gentamicin and two times when combined with ciprofloxacin. MIC values were not reduced by the combination of azidothymidine with cefotaxime or chloramphenicol. It has been established that azidothymidine has antibacterial activity against strains of K. pneumoniae: MIC50 – 1 μg/ml and MIC90 – 2 μg/ml. The MIC50 and MIC90 values for baicalin were > 256 μg/ml. A synergistic antibacterial effect was detected when azidothymidine was combined with gentamicin (ΣFIC 0.33–0.50). An additive effect (ΣFIC 0.65–0.84) was detected when azidothymidine was combined with ciprofloxacin. Baikalin reduced the MIC value of cefotaxime by half, and the MIC50 values for gentamicin also decreased by half. Baicalin did not affect the susceptibility of multidrug-resistant K. pneumoniae strains to ciprofloxacin and chloramphenicol. Synergism was detected in the combination of baicalin and cefotaxime (ΣFIC 0.52 – 0.75 – additive effect). Conclusions. The development of gradient diffusion strips with azidothymidine and baicalin makes it possible to simplify methods for assessing the joint action of combinations of these substances with antibiotics and to avoid time-consuming preparatory steps. Our study demonstrated that azidothymidine exhibits synergistic activity in combination with gentamicin and ciprofloxacin and baicalin – in combination with cefotaxime. Further studies are needed to evaluate the potential use of these combinations in practical healthcare

Holography in 4D (Super) Higher Spin Theories and a Test via Cubic Scalar Couplings

The correspondences proposed previously between higher spin gauge theories and free singleton field theories were recently extended into a more complete picture by Klebanov and Polyakov in the case of the minimal bosonic theory in D=4 to include the strongly coupled fixed point of the 3d O(N) vector model. Here we propose an N=1 supersymmetric version of this picture. We also elaborate on the role of parity in constraining the bulk interactions, and in distinguishing two minimal bosonic models obtained as two different consistent truncations of the minimal N=1 model that retain the scalar or the pseudo-scalar field. We refer to these models as the Type A and Type B models, respectively, and conjecture that the latter is holographically dual to the 3d Gross-Neveu model. In the case of the Type A model, we show the vanishing of the three-scalar amplitude with regular boundary conditions. This agrees with the O(N) vector model computation of Petkou, thereby providing a non-trivial test of the Klebanov-Polyakov conjecture.Comment: 30p

Dual giant gravitons in AdSm_m ×\times Yn^n (Sasaki-Einstein)

We consider BPS motion of dual giant gravitons on Ad$S_5\times Y^5$ where $Y^5$ represents a five-dimensional Sasaki-Einstein manifold. We find that the phase space for the BPS dual giant gravitons is symplectically isomorphic to the Calabi-Yau cone over $Y^5$, with the K\"{a}hler form identified with the symplectic form. The quantization of the dual giants therefore coincides with the K\"{a}hler quantization of the cone which leads to an explicit correspondence between holomorphic wavefunctions of dual giants and gauge-invariant operators of the boundary theory. We extend the discussion to dual giants in $AdS_4 \times Y^7$ where $Y^7$ is a seven-dimensional Sasaki-Einstein manifold; for special motions the phase space of the dual giants is symplectically isomorphic to the eight-dimensional Calabi-Yau cone.Comment: 14 pages. (v2) typo's corrected; factors of AdS radius reinstated for clarity; remarks about dual giant wavefunctions in T^{1,1} expanded and put in a new subsectio

Counting 1/8-BPS Dual-Giants

We count 1/8-BPS states in type IIB string theory on AdS_5 x S^5 background which carry three independent angular momenta on S^5. These states can be counted by considering configurations of multiple dual-giant gravitons up to N in number which share at least four supersymmetries. We map this counting problem to that of counting the energy eigen states of a system of N bosons in a 3-dimensional harmonic oscillator. We also count 1/8-BPS states with two independent non-zero spins in AdS_5 and one non-zero angular momentum on S^5 by considering configurations of arbitrary number of giant gravitons that share at least four supersymmetries.Comment: 19 page

Оказание медицинской помощи пациентам с акне. Результаты экспертизы качества медицинской помощи

Goal. To obtain information on typical errors in medical aid rendered to acne patients in dermatovenerology dispensaries in St. Petersburg in order to develop measures to improve the quality of medical aid rendered to this group of patients. Materials and methods. The authors conducted a special expert examination of 55 patients with acne who received treatment at St. Petersburg dermatovenerology dispensaries in 2013. The quality of medical aid was assessed using the Automated Expert Examination Technique (hereinafter referred to as AEET). Major results. The percentage of cases when medical aid of due quality was rendered to acne patients was 49%. Treatment and diagnostics errors prevailed in the structure of errors in medical aid. Errors in treatment were mainly a wrong combination of drugs, simultaneous administration of external and systemic antibacterial drugs, delayed comedolytic therapy and pathogenically infeasible therapy. Errors in diagnostics included absence of indications of the form and/or severity of acne. The most important error in the collection of information was absence of gynecology examinations for women to determine whether peroral contraceptives were necessary including in case of the administration of isotretinoin. Conclusion. The similarity of errors in medical aid rendered for acne as well as high percentage of errors relating to medical aid rendered to patients demand the development of consistent measures to improve the quality of medical aid rendered to such patients and repeated expert examination using preliminary (prompt) control of the quality of medical aid.Цель. Получение информации о типичных ошибках оказания медицинской помощи пациентам с акне в кожно-венерологических диспансерах (КВД) Санкт-Петербурга для разработки мер, направленных на улучшение качества медицинской помощи (КМП) данной группе пациентов. Материал и методы. Проведена тематическая экспертиза КМП 55 наблюдений пациентов с акне, которые получали лечение в КВД Санкт-Петербурга в 2013 г. Изучение КМП проводилось с применением Автоматизированной технологии экспертизы КМП. Результаты. Доля случаев оказания медицинской помощи надлежащего качества пациентам с акне составляла 49%. В структуре ошибок оказания медицинской помощи преобладали ошибки лечения и диагноза. Ошибки лечения были представлены преимущественно неверным сочетанием препаратов, наиболее часто одномоментным назначением антибактериальных препаратов для наружного и системного применения, поздним назначением комедолитической терапии, а также применением патогенетически необоснованной терапии. Ошибками постановки диагноза считали отсутствие указаний на форму и/или степень тяжести акне, наиболее важными ошибками сбора информации - отсутствие обследования женщин у гинеколога для решения вопроса о необходимости применения комбинированных оральных контрацептивов, в том числе и при назначении изотретиноина. Заключение. Сходство характера ошибок медицинской помощи при акне, а также их высокий удельный вес при оказании медицинской помощи пациентам требуют разработки системных мероприятий по улучшению КМП этим больным и повторной экспертизы с применением индикаторов промежуточного (оперативного) контроля КМП

At the horizon of a supersymmetric AdS_5 black hole: Isometries and half-BPS giants

The near-horizon geometry of an asymptotically AdS_5 supersymmetric black hole discovered by Gutowski and Reall is analysed. After lifting the solution to 10 dimensions, we explicitly solve the Killing spinor equations in both Poincare and global coordinates. It is found that exactly four supersymmetries are preserved which is twice the number for the full black hole. The full set of isometries is constructed and the isometry supergroup is shown to be SU(1,1|1) X SU(2) X U(3). We further study half-BPS configurations of D3-branes in the near-horizon geometry in Poincare and global coordinates. Both giant graviton probes and dual giant graviton probes are found.Comment: 26 pages. v2:Typos corrected, minor change

1/16-BPS Black Holes and Giant Gravitons in the AdS_5 X S^5 Space

We explore 1/16-BPS objects of type IIB string theory in AdS_5 * S^5. First, we consider supersymmetric AdS_5 black holes, which should be 1/16-BPS and have a characteristic that not all physical charges are independent. We point out that the Bekenstein-Hawking entropy of these black holes admits a remarkably simple expression in terms of (dependent) physical charges, which suggests its microscopic origin via certain Cardy or Hardy-Ramanujan formula. We also note that there is an upper bound for the angular momenta given by the electric charges. Second, we construct a class of 1/16-BPS giant graviton solutions in AdS_5 * S^5 and explore their properties. The solutions are given by the intersections of AdS_5 * S^5 and complex 3 dimensional holomorphic hyperspaces in C^{1+5}, the latter being the zero loci of three holomorphic functions which are homogeneous with suitable weights on coordinates. We investigate examples of giant gravitons, including their degenerations to tensionless strings.Comment: 25 pages, no figures, v2: references added, comments added in the conclusio

AdS Branes Corresponding to Superconformal Defects

We investigate an AdS_4 x L_2 D5-brane in AdS_5 x X_5 space-time, in the context of AdS/dCFT correspondence. Here, X_5 is a Sasaki-Einstein manifold and L_2 is a submanifold of X_5. This brane has the same supersymmetry as the 3-dimensional N=1 superconformal symmetry if L_2 is a special Legendrian submanifold in X_5. In this case, this brane is supposed to correspond to a superconformal wall defect in 4-dimensional N=4 super Yang-Mills theory. We construct these new string backgrounds and show they have the correct supersymmetry, also in the case with non-trivial gauge flux on L_2. The simplest new example is AdS_4 x T^2 brane in AdS_5 x S^5. We construct the brane solution expressing the RG flow between two different defects. We also perform similar analysis for an AdS_3 x L_3 M5-brane in AdS_4 x X_7, for a weak G_2 manifold X_7 and its submanifold L_3. This system has the same supersymmetry as 2-dimensional N=(1,0) global superconformal symmetry, if L_3 is an associative submanifold.Comment: 22 pages, LaTeX, 3 figures. v2: typos corrected, references added. v3: typos correcte