Рецидив гетеротопической оссификации в результате вывиха эндопротеза тазобедренного сустава: клинический случай

Background. Heterotopic ossification (HO) is the formation of mature bone in soft tissues. HO in the hip area can be a consequence of both injury to the nervous system and local trauma. After total hip arthroplasty HO develops in 30% of cases. The aim of the study is to demonstrate a rare clinical case of a recurrence of HO in patient after a primary total hip arthroplasty, accompanied by ankylosing. Case presentation. A 32-year-old patient was admitted to the clinic for revision hip arthroplasty with a diagnosis long-standing dislocation of the right hip joint endoprosthesis head, heterotopic ossification 3 years after dislocation. During the surgery, there were difficulties with the sciatic nerve dissection, as well as the structures of the endoprosthesis. We removed all the ossifications that obstructed the dislocation of the endoprosthesis. The patient had sciatic nerve neuropathy on the right lower limb with lesions of the fibular and tibial nerves on the background of edema. The patient was discharged on the 21st day. The presented clinical case is interesting because the patients relapse could be caused by a combination of various risk factors. Taking into account the fact that the injury was received as a result of an accident and the patient had a fracture of the bones of the contralateral shin, it could be the effect of a local hip injury that aggravated the process. Conclusions. This clinical observation highlights the importance of preventing possible complications after surgery and maintaining feedback with patients, especially those belonging to the high-risk group. It is likely that with adequate prevention of the HO formation and timely reduction of dislocation, the problems described in the article after primary total hip arthroplasty could have been avoided.Актуальность. Гетеротопическая оссификация (ГО) это формирование зрелой кости в мягких тканях. ГО в области тазобедренного сустава может быть следствием как повреждения нервной системы, так и локальной травмы. После тотального эндопротезирования тазобедренного сустава ГО развивается в 30% наблюдений. Целью публикации является демонстрация редкого клинического наблюдения пациента с рецидивом ГО после сложного первичного эндопротезирования тазобедренного сустава, сопровождающимся анкилозированием. Описание случая. Пациент 32 лет поступил в клинику для ревизионного эндопротезирования тазобедренного сустава с диагнозом застарелый вывих головки эндопротеза правого тазобедренного сустава, гетеротопическая оссификация спустя 3 года после вывиха. Во время операции были сложности с выделением седалищного нерва, а также структур эндопротеза. Нами были удалены все оссификаты, которые препятствовали вывиху эндопротеза. У пациента наблюдалась невропатия седалищного нерва справа с поражением малоберцового и большеберцового нервов на фоне отека. Пациент был выписан на 21-й день. Представленный клинический случай интересен тем, что у пациента рецидив ГО мог быть обусловлен комбинацией различных факторов риска. С учетом того, что травма была получена в результате ДТП и у пациента имелся перелом костей контралатеральной голени, нельзя исключить эффект местной травмы тазобедренного сустава, усугубившей процесс. Заключение. Данное клиническое наблюдение подчеркивает важность профилактики вероятных осложнений после операции и поддержания обратной связи с пациентами, особенно относящимися к группе высокого риска. Вполне вероятно, что при адекватной профилактике формирования ГО и своевременном вправлении вывиха описанных в статье проблем после первичного эндопротезирования удалось бы избежать

Micro Energy Complex Based on Wet-SteamTurbine

AbstractThis work is dedicated to the development of the micro energy complex concept based on a wet-steam microturbine and mixed use of conventional and unconventional energy sources for standalone supply of distributed energy consumer, adapted to Russia's climate condition. The development is stipulated by absence of low powered micro energy complexes (MEC) for standalone individual low rise energy consumers at the power supply market. This article describes the working out of the energy complex cycle arrangement, the choice of optimal power for a standalone consumer and the development of wet-steam micro turbin

Ultraviolet Complete Electroweak Model Without a Higgs Particle

An electroweak model with running coupling constants described by an energy dependent entire function is utraviolet complete and avoids unitarity violations for energies above 1 TeV. The action contains no physical scalar fields and no Higgs particle and the physical electroweak model fields are local and satisfy microcausality. The $W$ and $Z$ masses are compatible with a symmetry breaking $SU(2)_L\times U(1)_Y \rightarrow U(1)_{\rm em}$, which retains a massless photon. The vertex couplings possess an energy scale $\Lambda_W > 1$ TeV predicting scattering amplitudes that can be tested at the LHC.Comment: 19 pages, no figures, LaTex file. Equation and text corrected. Reference added. Results remain the same. Final version published in European Physics Journal Plus, 126 (2011

Non-Localizability and Asymptotic Commutativity

The mathematical formalism commonly used in treating nonlocal highly singular interactions is revised. The notion of support cone is introduced which replaces that of support for nonlocalizable distributions. Such support cones are proven to exist for distributions defined on the Gelfand-Shilov spaces $S^\beta$, where $0<\beta <1$ . This result leads to a refinement of previous generalizations of the local commutativity condition to nonlocal quantum fields. For string propagators, a new derivation of a representation similar to that of K\"{a}llen-Lehmann is proposed. It is applicable to any initial and final string configurations and manifests exponential growth of spectral densities intrinsic in nonlocalizable theories.Comment: This version is identical to the initial one whose ps and pdf files were unavailable, with few corrections of misprint

Изучение видового разнообразия бактерий рода Bifidobacterium кишечной микрофлоры с использованием метода MALDI-TOF масс-спектрометрии

Background: The members of genus Bifidobacterium represent a significant part of intestinal microbiota in adults and predominate in infants. Species repertoire of the intestinal bifidobacteria is known to be subjected to major changes with age; however, many details of this process are still to be elucidated.Objective: Our aim was to study the diversity of intestinal bifidobacteria and changes of their qualitative and quantitative composition characteristics during the process of growing up using MALDI-TOF mass-spectrometric analysis of pure bacterial cultures.Methods: A cross-sectional study of bifidobacteria in the intestinal microbiota was performed in 93 healthy people of the ages from 1 month to 57 years. Strains were identified using Microflex LT MALDI-TOF MS, the confirmation was performed by 16S rRNA gene fragment sequencing.Results: 93% of isolated bifidobacterial strains were successfully identified using MALDI-TOF mass-spectrometry. At least two of the strains from each species were additionally identified by 16S rRNA gene fragment sequencing, in all of the cases the results were the same. It was shown that the total concentration of bifidobacteria decreases with age (p 0.001) as well as the frequency of isolation of Bifidobacterium bifidum (p =0.020) and Bifidobacterium breve (p 0.001), and the frequency of isolation of Bifidobacterium adolescentis, increases (p 0.001), representing the continuous process of transformation of microbiota.Conclusion: The method of MALDI-TOF mass spectrometry demonstrated the ability to perform rapid and reliable identification of bifidobacteria that allowed the study of changes in the quantitative and qualitative characteristics of human microbiota in the process of growing up.Представители рода Bifidobacterium представляют значительную часть микрофлоры кишечника взрослых людей и численно доминируют в микрофлоре младенцев. Известно, что видовой состав кишечных бифидобактерий подвергается сильным изменениям с возрастом, однако многие детали этого процесса остаются неясными.Цель исследования: изучить видовое разнообразие бифидобактерий кишечника и изменения их качественного и количественного состава в процессе взросления человека при помощи технологии MALDI-TOF масс-спектрометрического анализа белковых профилей чистых культур.Методы: кросс-секционное исследование разнообразия бифидобактерий в составе нормальной микрофлоры кишечника проведено у 93 человек в возрасте от 1 мес до 57 лет. Осуществляли выделе- ние чистых культур и их идентификацию на приборе Microflex LT MALDI-TOF MS (Bruker Daltonics, Германия), подтверждение реализовывали с использованием секвенирования фрагмента гена 16S рРНК.Результаты: с применением MALDI-TOF масс-спектрометрии было успешно идентифицировано 93% выделенных штаммов бифидобактерий. Минимум по 2 представителя от каждого из видов были дополнительно определены методом секвенирования фрагмента гена 16SрРНК; во всех случаях результаты методов совпали. Показано, что с возрастом происходит снижение общей концентрации бифидобактерий (p 0,001), уменьшается встречаемость видов Bifidobacterium bifidum (p =0,020) и Bifidobacterium breve (p 0,001), а встречаемость вида Bifidobacterium adolescentis увеличивается (p 0,001), отражая постепенные процессы перестройки микрофлоры.Заключение: метод MALDI-TOF масс-спектрометрии показал возможность быстрой и надежной идентификации бифидобактерий, позволившей провести исследование изменений количественных и качественных показателей микрофлоры человека в процессе взрослени

Volume element structure and roton-maxon-phonon excitations in superfluid helium beyond the Gross-Pitaevskii approximation

We propose a theory which deals with the structure and interactions of volume elements in liquid helium II. The approach consists of two nested models linked via parametric space. The short-wavelength part describes the interior structure of the fluid element using a non-perturbative approach based on the logarithmic wave equation; it suggests the Gaussian-like behaviour of the element's interior density and interparticle interaction potential. The long-wavelength part is the quantum many-body theory of such elements which deals with their dynamics and interactions. Our approach leads to a unified description of the phonon, maxon and roton excitations, and has noteworthy agreement with experiment: with one essential parameter to fit we reproduce at high accuracy not only the roton minimum but also the neighboring local maximum as well as the sound velocity and structure factor.Comment: 9 pages, 6 figure

Bosonization in Particle Physics

Path integral techniques in collective fields are shown to be a useful analytical tool to reformulate a field theory defined in terms of microscopic quark (gluon) degrees of freedom as an effective theory of collective boson (meson) fields. For illustrations, the path integral bosonization approach is applied to derive a (non)linear sigma model from a Nambu-Jona-Lasinio (NJL) quark model. The method can be extended to include higher order derivative terms in meson fields or heavy-quark symmetries. It is also approximately applicable to QCD.Comment: 12 pages, LaTeX, uses lamuphys.sty, 5 LaTeX figures, talk given at the Workshop "Field Theoretical Tools in Polymer and Particle Physics", University Wuppertal, June 17-19, 199

On The Universality Class Of Little String Theories

We propose that Little String Theories in six dimensions are quasilocal quantum field theories. Such field theories obey a modification of Wightman axioms which allows Wightman functions (i.e. vacuum expectation values of products of fundamental fields) to grow exponentially in momentum space. Wightman functions of quasilocal fields in x-space violate microlocality at short distances. With additional assumptions about the ultraviolet behavior of quasilocal fields, one can define approximately local observables associated to big enough compact regions. The minimum size of such a region can be interpreted as the minimum distance which observables can probe. We argue that for Little String Theories this distance is of order {\sqrt N}/M_s.Comment: 25 pages, late

f0(980) meson as a K bar K molecule in a phenomenological Lagrangian approach

We discuss a possible interpretation of the f0(980) meson as a hadronic molecule - a bound state of K and bar K mesons. Using a phenomenological Lagrangian approach we calculate the strong f0(980) to pi pi and electromagnetic f0(980) to gamma gamma decays. The compositeness condition provides a self-consistent method to determine the coupling constant between f0 and its constituents, K and bar K. Form factors governing the decays of the f0(980) are calculated by evaluating the kaon loop integrals. The predicted f0(980) to pi pi and f0(980) to gamma gamma decay widths are in good agreement with available data and results of other theoretical approaches.Comment: 21 pages, 11 figures, revised version accepted for publication in Eur. Phys. J.

Automatic regularization by quantization in reducible representations of CCR: Point-form quantum optics with classical sources

Electromagnetic fields are quantized in manifestly covariant way by means of a class of reducible representations of CCR. $A_a(x)$ transforms as a Hermitian four-vector field in Minkowski four-position space (no change of gauge), but in momentum space it splits into spin-1 massless photons (optics) and two massless scalars (similar to dark matter). Unitary dynamics is given by point-form interaction picture, with minimal-coupling Hamiltonian constructed from fields that are free on the null-cone boundary of the Milne universe. SL(2,C) transformations and dynamics are represented unitarily in positive-norm Hilbert space describing $N$ four-dimensional oscillators. Vacuum is a Bose-Einstein condensate of the $N$-oscillator gas. Both the form of $A_a(x)$ and its transformation properties are determined by an analogue of the twistor equation. The same equation guarantees that the subspace of vacuum states is, as a whole, Poincar\'e invariant. The formalism is tested on quantum fields produced by pointlike classical sources. Photon statistics is well defined even for pointlike charges, with UV/IR regularizations occurring automatically as a consequence of the formalism. The probabilities are not Poissonian but of a R\'enyi type with $\alpha=1-1/N$. The average number of photons occurring in Bremsstrahlung splits into two parts: The one due to acceleration, and the one that remains nonzero even if motion is inertial. Classical Maxwell electrodynamics is reconstructed from coherent-state averaged solutions of Heisenberg equations. Static pointlike charges polarize vacuum and produce effective charge densities and fields whose form is sensitive to both the choice of representation of CCR and the corresponding vacuum state.Comment: 2 eps figures; in v2 notation in Eq. (39) and above Eq. (38) is correcte