Прогнозирование устойчивости ремиссий при эндогенных психических заболеваниях: перспективы использования функционального диагноза

Results of research of 83 patients with schizophrenia and affective disorders show, that some components of the functional diagnosis can serve as predictors to stability of remissions. Social characteristics — family and concerning to the nearest environment outside of family are most significant in this respect.Результаты исследования 83 больных шизофренией и аффективными расстройствами показывают, что некоторые компоненты функционального диагноза могут служить предикторами устойчивости ремиссий. Наиболее значимы в этом отношении социальные характеристики — семейные и относящиеся к ближайшему окружению вне семьи

Observation of nuclei with energies 8-30 MeV per nucleon in the Earth's magnetosphere at the altitudes 350 KM

Observations of the flux of nuclei with an energy of IO MeV per nucleon on the Salyut-7 Station in September 1984 are presented. The observed flux is smaller by a factor of 50 than the flux detected in May, 1981

LIPID PROFILE AND HEMORHEOLOGY DYNAMICS IN PATIENTS WITH LOWER EXTREMITY PERIPHERAL ARTERY DISEASE IN THE PREOPERATIVE AND POSTOPERATIVE PERIOD

The objective of the study was to evaluate the lipid and hemostatic profile in patients with peripheral artery disease of lower extremities at different levels of lesion and methods of surgery.Materials and methods. 330 male patients with peripheral artery disease of lower extremities arteries of II b — III degree were examined: group I consisted of 140 patients with lesions of the femoral-popliteal arterial segment, who underwent femoralpopliteal bypass surgery (58.64±7.73 years), group II — 97 patients with occlusive-stenotic lesions of the aorto-iliac segment, who underwent aortofemoral bypass surgery (56.82±6.69 years), group III — 93 patients with occlusive stenotic changes of the iliac arteries, who underwent transluminal balloon angioplasty and stenting of the iliac arteries. The examination of patients included general clinical, instrumental and laboratory methods with the assessment of lipid profile fractions and plasma-coagulation level of hemostasis.Results. The provided examination showed that patients with peripheral artery disease have disorders of the blood lipid profile, which have significant differences depending on the severity and localization of occlusive-stenotic lesions of the aorta and main arteries. Lipid imbalance persists after correction of arterial blood flow. Significant changes in the hemostatic profile in all groups in the postoperative period were revealed, which were characterized by hypercoagulation in the form of a significant increase in the concentration of fibrinogen, reducing the activity of antithrombin III, shortening of thrombin time in groups I and II and reducing spontaneous fibrinolysis in groups I and II. Thrombin time and spontaneous fibrinolysis in group III increased relative to preoperative values. Open interventions in the volume of femoral-popliteal bypass surgery were accompanied by a more pronounced inhibition of fibrinolysis in comparison with minimally invasive interventions, and in endovascular procedure the anticoagulant potential was more depressed. Open reconstruction of the iliac segment was associated with a large reduction in thrombin time, but less inhibition of anticoagulant potential, compared with endovascular technique, due to large damage to the endothelium.Conclusion. It is necessary to monitor the lipid and hemostatic profile both before and after surgery in patients, admitted to the hospital for reconstructive surgery on the aorta and main arteries of the lower extremities, in order to develop an effective personalized drug prevention of lower extremity peripheral artery disease progression and to prevent the development of thrombotic and stenotic complications of the arterial reconstruction zone

Substantiation of Organizational and Economic Complex for Increase of Social Responsibility of Business in Ukraine

The object of research is the organizational and economic processes of socialization of Ukrainian business. One of the most problematic areas is the formation of an adequate strategy for the behavior of Ukrainian business in terms of the burden on the environment and limiting the negative impact on ecosystems.In the course of the research, such methods of scientific research were used: bibliographic; monographic; method of logical generalization; calculated; comparative and system approach method.The dynamics of Ukraine's position on the Global Competitiveness Index is analyzed, which also takes into account social initiatives of business. It is established that despite positive trends, the initiative in taking on the companies' obligations for sustainable development and responsibility to the society since 2016 in Ukraine tends to decrease.It is determined that the advantages of a socially responsible business policy for an enterprise are:growth of the company's positive image;improving the quality of business management;increase of professionalism and development of personnel potential;increase of investment attractiveness;creation of mutually beneficial relations with the authorities;possibility of obtaining additional benefits;expansion of partnerships in the business environment;ensuring financial security.In order to increase the social responsibility of business in Ukraine, it is necessary to implement the following activities:carrying out environmental and social audit;reforming the reporting system in accordance with International standards and practices;municipal partnership;formation of a system for informing the public about social and charitable projects;organization of an independent public examination of social projects;adaptation of the world experience of social entrepreneurship.Economic instruments for solving this issue are proposed, namely: the provision of preferences for socially-oriented business; material responsibility for harming the social interests of society; environmental insurance; development of proposals of local authorities on the programs of social development of regions.Thanks to the interaction of the state and entrepreneurship on the principles of partnership, as well as the imitation of successful experience in introducing socially-oriented standards of doing business in companies from different countries of the world, the prerequisites for sustainable development will be created. These prerequisites are based on the responsibility of business entities to the environment and society. At the same time, a positive impact will not only be on society and the environment, but will also contribute to improving the economic efficiency of the business due to the growth of public confidence

Expanded Brain CT Dataset for the Development of AI Systems for Intracranial Hemorrhage Detection and Classification

Intracranial hemorrhage (ICH) is a dangerous life-threatening condition leading to disability. Timely and high-quality diagnosis plays a huge role in the course and outcome of this disease. The gold standard in determining ICH is computed tomography. This method requires a prompt involvement of highly qualified personnel, which is not always possible, for example, in case of a staff shortage or increased workload. In such a situation, every minute counts, and time can be lost. The solution to this problem seems to be a set of diagnostic decisions, including the use of artificial intelligence, which will help to identify patients with ICH in a timely manner and provide prompt and quality medical care. However, the main obstacle to the development of artificial intelligence is a lack of high-quality datasets for training and testing. In this paper, we present a dataset including 800 brain CT scans consisting of multiple series of DICOM images with and without signs of ICH, enriched with clinical and technical parameters, as well as the methodology of its generation utilizing natural language processing tools. The dataset is publicly available, which contributes to increased competition in the development of artificial intelligence systems and their advancement and quality improvement

Fieldpractice in Higher Education System. Resume of IV International Conference in the Crimea

Brief information on the IV International Conference Field Practice in the Higher Education System held in the Crimea. Field practice is a part of educational program when students go to other regions in summer to apply on-site the competences and skills they obtained. Field practice is widely used in training of geologists, biologists, geophysicists, historians etc