1,630 research outputs found
Injection locking of two frequency-doubled lasers with 3.2 GHz offset for driving Raman transitions with low photon scattering in Ca
We describe the injection locking of two infrared (794 nm) laser diodes which
are each part of a frequency-doubled laser system. An acousto-optic modulator
(AOM) in the injection path gives an offset of 1.6 GHz between the lasers for
driving Raman transitions between states in the hyperfine split (by 3.2 GHz)
ground level of Ca. The offset can be disabled for use in
Ca. We measure the relative linewidth of the frequency-doubled beams
to be 42 mHz in an optical heterodyne measurement. The use of both injection
locking and frequency doubling combines spectral purity with high optical
power. Our scheme is applicable for providing Raman beams across other ion
species and neutral atoms where coherent optical manipulation is required.Comment: 3 pages, 3 figure
High-fidelity quantum logic gates using trapped-ion hyperfine qubits
We demonstrate laser-driven two-qubit and single-qubit logic gates with
fidelities 99.9(1)% and 99.9934(3)% respectively, significantly above the
approximately 99% minimum threshold level required for fault-tolerant quantum
computation, using qubits stored in hyperfine ground states of calcium-43 ions
held in a room-temperature trap. We study the speed/fidelity trade-off for the
two-qubit gate, for gate times between 3.8s and 520s, and develop a
theoretical error model which is consistent with the data and which allows us
to identify the principal technical sources of infidelity.Comment: 1 trap, 2 ions, 3 nines. Detailed write-up of arXiv:1406.5473
including single-qubit gate data als
Optimizing the performance of thermionic devices using energy filtering
Conventional thermionic power generators and refrigerators utilize a barrier
in the direction of transport to selectively transmit high-energy electrons.
Here we show that the energy spectrum of electrons transmitted in this way is
not optimal, and we derive the ideal energy spectrum for operation in the
maximum power regime. By using suitable energy filters, such as resonances in
quantum dots, the power of thermionic devices can, in principle, be improved by
an order of magnitude.Comment: 3 pages, 2 figure
A microfabricated ion trap with integrated microwave circuitry
We describe the design, fabrication and testing of a surface-electrode ion
trap, which incorporates microwave waveguides, resonators and coupling elements
for the manipulation of trapped ion qubits using near-field microwaves. The
trap is optimised to give a large microwave field gradient to allow
state-dependent manipulation of the ions' motional degrees of freedom, the key
to multiqubit entanglement. The microwave field near the centre of the trap is
characterised by driving hyperfine transitions in a single laser-cooled 43Ca+
ion.Comment: 4 pages, 5 figure
High-fidelity preparation, gates, memory and readout of a trapped-ion quantum bit
We implement all single-qubit operations with fidelities significantly above
the minimum threshold required for fault-tolerant quantum computing, using a
trapped-ion qubit stored in hyperfine "atomic clock" states of Ca.
We measure a combined qubit state preparation and single-shot readout fidelity
of 99.93%, a memory coherence time of seconds, and an average
single-qubit gate fidelity of 99.9999%. These results are achieved in a
room-temperature microfabricated surface trap, without the use of magnetic
field shielding or dynamic decoupling techniques to overcome technical noise.Comment: Supplementary Information included. 6 nines, 7 figures, 8 page
Microwave control electrodes for scalable, parallel, single-qubit operations in a surface-electrode ion trap
We propose a surface ion trap design incorporating microwave control
electrodes for near-field single-qubit control. The electrodes are arranged so
as to provide arbitrary frequency, amplitude and polarization control of the
microwave field in one trap zone, while a similar set of electrodes is used to
null the residual microwave field in a neighbouring zone. The geometry is
chosen to reduce the residual field to the 0.5% level without nulling fields;
with nulling, the crosstalk may be kept close to the 0.01% level for realistic
microwave amplitude and phase drift. Using standard photolithography and
electroplating techniques, we have fabricated a proof-of-principle electrode
array with two trapping zones. We discuss requirements for the microwave drive
system and prospects for scalability to a large two-dimensional trap array.Comment: 8 pages, 6 figure
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Corrigendum: a new strain collection for improved expression of outer membrane proteins
Cost-utility of transcatheter aortic valve implantation for inoperable patients with severe aortic stenosis treated by medical management: a UK cost-utility analysis based on patient-level data from the ADVANCE study.
OBJECTIVE: To use patient-level data from the ADVANCE study to evaluate the cost-effectiveness of transcatheter aortic valve implantation (TAVI) compared to medical management (MM) in patients with severe aortic stenosis from the perspective of the UK NHS.
METHODS: A published decision-analytic model was adapted to include information on TAVI from the ADVANCE study. Patient-level data informed the choice as well as the form of mathematical functions that were used to model all-cause mortality, health-related quality of life and hospitalisations. TAVI-related resource use protocols were based on the ADVANCE study. MM was modelled on publicly available information from the PARTNER-B study. The outcome measures were incremental cost-effectiveness ratios (ICERs) estimated at a range of time horizons with benefits expressed as quality-adjusted life-years (QALY). Extensive sensitivity/subgroup analyses were undertaken to explore the impact of uncertainty in key clinical areas.
RESULTS: Using a 5-year time horizon, the ICER for the comparison of all ADVANCE to all PARTNER-B patients was £13 943 per QALY gained. For the subset of ADVANCE patients classified as high risk (Logistic EuroSCORE >20%) the ICER was £17 718 per QALY gained). The ICER was below £30 000 per QALY gained in all sensitivity analyses relating to choice of MM data source and alternative modelling approaches for key parameters. When the time horizon was extended to 10 years, all ICERs generated in all analyses were below £20 000 per QALY gained.
CONCLUSION: TAVI is highly likely to be a cost-effective treatment for patients with severe aortic stenosis
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