27 research outputs found

    Studies for increasing fertility on second crop of rice [İkinci ürün çeltikte fertilitenin artirilmasi üzerine araştirmalar]

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    Selection was done on the basis of certain morphological, phenological and technological properties, in the studies conductted for increase of fertility in second crop of rice under Menemen ecological conditions during the year 1990-1991. Amongst 16 genotypes studies 2 genotypes found suitable for second crop of rice due to their resistance against extremly high temperature which causes sterility and determined as having high fertility were sent to "Variety Testing and Relies Institute Ankara". The project was completed with the second year success in the regional varietal yield

    Ischemia modified albumin increase indicating cardiac damage after experimental subarachnoid hemorrhage

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    Background: Cardiac complications are often developed after subarachnoid hemorrhage (SAH) and may cause sudden death of the patient. There are reports in the literature addressing ischemia modified albumin (IMA) as an early and useful marker in the diagnosis of ischemic heart events. The aim of this study is to evaluate serum IMA by using the albumin cobalt binding (ACB) test in the first, second, and seventh days of experimental SAH in rats.Twenty-eight Wistar albino rats were divided into four groups each consisting of seven animals. These were classified as control group, 1st, 2nd and 7th day SAH groups. SAH was done by transclival basilar artery puncture. Blood samples were collected under anesthesia from the left ventricles of the heart using the cardiac puncture method for IMA measurement. Histopathological examinations were performed on the heart and lung tissues. Albumin with by colorimetric, creatine kinase (CK), aspartate aminotransferase (AST), lactate dehydrogenase (LDH) were determined on an automatic analyser using the enzymatic method. IMA using by ACB test was detected with spectrophotometer.Results: Serum IMA (p = 0.044) in seventh day of SAH were higher compared to the control group. Total injury scores of heart and lung tissue, also myocytolysis at day 7 were significantly higher than control group (p = 0.001, p = 0.001, p = 0.001), day 1 (p = 0.001, p = 0.001, p = 0.001) and day 2 (p = 0.001, p = 0.007, p = 0.001). A positive correlation between IMA - myocytolysis (r = 0.48, p = 0.008), and between IMA - heart tissue total injury score (r = 0.41, p = 0.029) was found.Conclusion: The results revealed that increased serum IMA may be related to myocardial stress after SAH. © 2014 Açi{dotless}kgöz et al.; licensee BioMed Central Ltd

    Prevalence of alcohol dependence and abuse in a general hospital; Sensitivity and specificity of Mast

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    Aim: Alcohol abuse and dependence is an important public health concern in most countries. It is also a big problem among the hospitalized patients. Method: This study was undertaken to determine the number of the patients with alcohol related problems in a general hospital sample, to compare the prevalence rate among clinics, to determine the sensitivity and specificity of MAST (Michigan Alcoholism Screening Test) for an inpatient sample. The data were collected from 13 inpatient clinics of Ankara Numune Research and Training Hospital. Result: A sample of 800 patients was enrolled in the study. 60 patients were (%7,5) diagnosed alcohol addiction and 11 were (%1,4) diagnosed as alcohol abuse. Alcohol addiction was most common in gastroenterology clinic. MAST sensitivity and specificity were found 0,74 and 0,98 respectively. Conclusion: MAST might be a useful instrument for screening alcohol related problems in a general hospital setting

    Effect of montelukast treatment on serum paraoxonase activity in asthmatic children

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    Montelukast, widely used in the treatment of asthma, is a selective and potent oral cysteinyl leukotriene-1 receptor antagonist. In this study, we investigated the effects of montelukast on oxidative stress and antioxidant defense in childhood asthma by measuring malondialdehyde and the paraoxonase activity. Twenty-five children with mild to moderate atopic asthma and 25 nonatopic children as controls were enrolled in the study. Asthmatic children were treated with montelukast, 5 mg tablets, for one month. Serum paraoxonase, malondialdehyde and high-density lipoprotein (HDL) cholesterol levels were measured before and after treatment. Serum paraoxonase and paraoxonase/HDL ratios were significantly increased after montelukast treatment. These parameters were significantly higher when compared with the normal subjects. Although montelukast treatment caused an enhancement in serum malondialdehyde, this increase did not reach statistical significance between the groups. The present study clearly demonstrates that montelukast increases paraoxonase activity in children with bronchial asthma. However, for better understanding of this enhancement, additional in vivo and in vitro studies are required. © TÜBİTAK
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