Optimal Drug Policy in Low-Income Neighborhoods

Part of the debate over the control of drug activity in cities is concerned with the effectiveness of implementing demand- versus supply-side drug policies. This paper is motivated by the relative lack of research providing formal economic underpinning for the implementation of either policy. We construct a simple model of drug activity, in which the drug price and the distribution of population in a community are determined according to a career choice rule and a predetermined drug demand. Three potential government objectives are considered. We find that both demand- and supply-side policies have theoretical support under different community conditions. While the demand-side policy discourages active drug sellers, the supply-side policy has an additional drug-dealing replacement effect on inducing potential entry of drug dealers. In low-income neighborhoods, demand-side policy is more effective if the drug problem is more sever or if the government objective is to deter dealer entry or to promote community's aggregate income rather than minimizing active drug selling.

Fractional Quantum Hall Effect in Topological Flat Bands with Chern Number Two

Recent theoretical works have demonstrated various robust Abelian and non-Abelian fractional topological phases in lattice models with topological flat bands carrying Chern number C=1. Here we study hard-core bosons and interacting fermions in a three-band triangular-lattice model with the lowest topological flat band of Chern number C=2. We find convincing numerical evidence of bosonic fractional quantum Hall effect at the $\nu=1/3$ filling characterized by three-fold quasi-degeneracy of ground states on a torus, a fractional Chern number for each ground state, a robust spectrum gap, and a gap in quasihole excitation spectrum. We also observe numerical evidence of a robust fermionic fractional quantum Hall effect for spinless fermions at the $\nu=1/5$ filling with short-range interactions.Comment: 5 pages, 7 figures, with Supplementary Materia

Binding Transition in Quantum Hall Edge States

We study a class of Abelian quantum Hall (QH) states which are topologically unstable (T-unstable). We find that the T-unstable QH states can have a phase transition on the edge which causes a binding between electrons and reduces the number of gapless edge branches. After the binding transition, the single-electron tunneling into the edge gains a finite energy gap, and only certain multi-electron co-tunneling (such as three-electron co-tunneling for $\nu=9/5$ edges) can be gapless. Similar phenomenon also appear for edge state on the boundary between certain QH states. For example edge on the boundary between $\nu=2$ and $\nu=1/5$ states only allow three-electron co-tunneling at low energies after the binding transition.Comment: 4 pages, RevTeX, 1 figur

Vacuum Energy Density and Cosmological Constant in dS Brane World

We discuss the vacuum energy density and the cosmological constant of dS$_5$ brane world with a dilaton field. It is shown that a stable AdS$_4$ brane can be constructed and gravity localization can be realized. An explicit relation between the dS bulk cosmological constant and the brane cosmological constant is obtained. The discrete mass spectrum of the massive scalar field in the AdS$_4$ brane is used to acquire the relationship between the brane cosmological constant and the vacuum energy density. The vacuum energy density in the brane gotten by this method is in agreement with astronomical observations.Comment: 16 pages,4 figure

Probing the relative contribution of the first and second responses to sensory gating indices: A meta‐analysis

Sensory gating deficit in schizophrenia patients has been well‐documented. However, a central conceptual issue, regarding whether the gating deficit results from an abnormal initial response (S1) or difficulty in attenuating the response to the repeating stimulus (S2), raise doubts about the validity and utility of the S2/S1 ratio as a measure of sensory gating. This meta‐analysis study, therefore, sought to determine the consistency and relative magnitude of the effect of the two essential components (S1 and S2) and the ratio. The results of weighted random effects meta‐analysis revealed that the overall effect sizes for the S1 amplitude, S2 amplitude, and P50 S2/S1 ratio were −0.19 (small), 0.65 (medium to large), and 0.93 (large), respectively. These results confirm that the S2/S1 ratio and the repeating (S2) stimulus differ robustly between schizophrenia patients and healthy controls in contrast to the consistent but smaller effect size for the S1 amplitude. These findings are more likely to reflect defective inhibition of repeating redundant input rather than an abnormal response to novel stimuli.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87078/1/j.1469-8986.2010.01168.x.pd

Fluctuations in Gene Regulatory Networks as Gaussian Colored Noise

The study of fluctuations in gene regulatory networks is extended to the case of Gaussian colored noise. Firstly, the solution of the corresponding Langevin equation with colored noise is expressed in terms of an Ito integral. Then, two important lemmas concerning the variance of an Ito integral and the covariance of two Ito integrals are shown. Based on the lemmas, we give the general formulae for the variances and covariance of molecular concentrations for a regulatory network near a stable equilibrium explicitly. Two examples, the gene auto-regulatory network and the toggle switch, are presented in details. In general, it is found that the finite correlation time of noise reduces the fluctuations and enhances the correlation between the fluctuations of the molecular components.Comment: 10 pages, 4 figure

Experiments on the Fermi to Tomonaga-Luttinger liquid transition in quasi-1D systems

We present experimental results on the tunneling into the edge of a two dimensional electron gas (2DEG) obtained with GaAs/AlGaAs cleaved edge overgrown structures. The electronic properties of the edge of these systems can be described by a one-dimensional chiral Tomonaga-Luttinger liquid when the filling factor of the 2DEG is very small. Here we focus on the region where the Tomonaga-Luttinger liquid breaks down to form a standard Fermi liquid close to $\nu=1$ and show that we recover a universal curve, which describes all existing data.Comment: 5 pages, localisation 2002, conference proceeding

Critical points in edge tunneling between generic FQH states

A general description of weak and strong tunneling fixed points is developed in the chiral-Luttinger-liquid model of quantum Hall edge states. Tunneling fixed points are a subset of `termination' fixed points, which describe boundary conditions on a multicomponent edge. The requirement of unitary time evolution at the boundary gives a nontrivial consistency condition for possible low-energy boundary conditions. The effect of interactions and random hopping on fixed points is studied through a perturbative RG approach which generalizes the Giamarchi-Schulz RG for disordered Luttinger liquids to broken left-right symmetry and multiple modes. The allowed termination points of a multicomponent edge are classified by a B-matrix with rational matrix elements. We apply our approach to a number of examples, such as tunneling between a quantum Hall edge and a superconductor and tunneling between two quantum Hall edges in the presence of interactions. Interactions are shown to induce a continuous renormalization of effective tunneling charge for the integrable case of tunneling between two Laughlin states. The correlation functions of electronlike operators across a junction are found from the B matrix using a simple image-charge description, along with the induced lattice of boundary operators. Many of the results obtained are also relevant to ordinary Luttinger liquids.Comment: 23 pages, 6 figures. Xiao-Gang Wen: http://dao.mit.edu/~we

Persistent edge currents for paired quantum hall states

We study the behavior of the persistent edge current for paired quantum Hall states on the cylinder. We show that the currents are periodic with the unit flux $\phi_0=hc/e$. At low temperatures, they exhibit anomalous oscillations in their flux dependence.The shape of the functions converges to the sawtooth function periodic with $\phi_0/2$.Comment: RevTex 8 pages. one figure. to appear in Phys.Rev.