Review of Solar and Reactor Neutrinos

Over the last several years, experiments have conclusively demonstrated that neutrinos are massive and that they mix. There is now direct evidence for $\nu_e$s from the Sun transforming into other active flavors while en route to the Earth. The disappearance of reactor $\bar{\nu}_e$s, predicted under the assumption of neutrino oscillation, has also been observed. In this paper, recent results from solar and reactor neutrino experiments and their implications are reviewed. In addition, some of the future experimental endeavors in solar and reactor neutrinos are presented.Comment: Proceedings of the XXII International Symposium on Lepton and Photon Interactions at High Energy (Lepton-Photon 2005, June 30 to July 5, 2005, Uppsala, Sweden). 11 figures, 5 table

Prospects for studying the solar CNO cycle by means of a lithium neutrino detector

Lithium detectors have a high sensitivity to CNO neutrinos from the Sun. The present experimental data and prospects for future experiments on the detection of CNO neutrinos are discussed. A nonstationary case is considered when the flux of 13N neutrinos is higher than the standard solar model predicts due to the influx of fresh material from the peripheral layers to the solar core.Comment: 12 pages, 5 figures, a thoroughly revised version, reported at International Symposium "Physics of Massive Neutrinos" at MILOS (Greece) 19-23 May 200

Thyroid-Associated Orbitopathy and Biomarkers: Where We Are and What We Can Hope for the Future.

Thyroid-associated orbitopathy (TAO) is the most common autoimmune disease of the orbit. It occurs more often in patients presenting with hyperthyroidism, characteristic of Graves' disease, but may be associated with hypothyroidism or euthyroidism. The diagnosis of TAO is based on clinical orbital features, radiological criteria, and the potential association with thyroid disease. To date, there is no specific marker of the orbital disease, making the early diagnosis difficult, especially if the orbital involvement precedes the thyroid dysfunction. The goal of this review is to present the disease and combine the available data in the literature concerning investigation of TAO biomarkers. Despite the progress done in the understanding of TAO disease, some important pieces are still missing. Typically, for the future, major efforts have to be done in the discovery of new biomarkers, validation of the suspected candidates on multicenter cohorts with standardized methodologies, and establishment of their clinical performances on the specific clinical application fields in order to improve not only the management of the TAO patients but also the therapeutic options and follow-up

Status of the Solar Neutrino Puzzle

Using the latest results from the solar neutrino experiments and a few standard assumptions, I show that the popular solar models are ruled out at the 3$\sigma$ level or at least TWO of the experiments are incorrect. Alternatively, one of the assumptions could be in error. These assumptions are spelled out in detail as well as how each one affects the argument.Comment: Latex, 8 pages + 4 uuencoded figures, minor changes made, FERMILAB-PUB/273-

Neopterin plasma concentrations in patients with aneurysmal subarachnoid hemorrhage: Correlation with infection and long-term outcome

© AANS, 2016. Objective Aneurysmal subarachnoid hemorrhage (aSAH) is associated with high rates of mortality and morbidity. The main predictor for the poor outcome is the World Federation of Neurosurgical Societies (WFNS) scale. However, this scale does not take into account proinflammatory events, such as infection occurring after the aSAH, which could modify the long-term status of patients. The aim of this study was to evaluate neopterin as an inflammatory biomarker for outcome and infection prediction in aSAH patients. Methods Plasma concentrations of neopterin were measured in 61 aSAH patients (22 male and 39 female; mean age [± SD] 52.8 ± 11.8 years) using a commercial ELISA kit. Samples were collected daily for 10 days. Outcome at 12 months was determined using the Glasgow Outcome Scale (GOS) and dichotomized as poor (GOS score 1, 2, or 3) or good (GOS score 4 or 5). Infection was determined by the presence of a positive bacterial culture. Results Patients with poor outcome at 12 months had higher concentrations of neopterin than patients with good outcome. In the same way, patients who had an infection during the hospitalization had significantly higher concentrations of neopterin than patients without infection (p = 0.001). Moreover, neopterin concentrations were significantly (p < 0.008) elevated in infected patients 2 days before infection detection and antibiotic therapy. Conclusions Neopterin is an efficient outcome predictor after aSAH. Furthermore, it is able to differentiate between infected and uninfected patients as early as 2 days before clinical signs of infection, facilitating earlier antibiotic therapy and better management

Semi-Empirical Bound on the Chlorinr-37 Solar Neutrino Experiment

The Kamiokande measurement of energetic Boron-8 neutrinos from the sun is used to set a lower bound on the contribution of the same neutrinos to the signal in the \Chlorine\ experiment. Implications for Beryllium-7 neutrinos are discussed.Comment: Latex, 6 pages + 1 postscript figure (included). UTAPHY-HEP-

Polyethylene imine-based receptor immobilization for label free bioassays

Polyethylene imine (PEI) based immobilization of antibodies is described and the concept is proved on the label free assay of C-Reactive Protein (CRP). This novel immobilization method is composed of a hyperbranched PEI layer which was deposited at a high pH (9.5) on the sensor surface. The free amino groups of PEI were derivatized with neutravidin by Biotin N-hydroxysuccinimide ester and the biotinylated anti-CRP antibody immobilized on this layer. Direct binding assay of recombinant CRP was successfully performed in the low μg/ml concentrations using a label free optical waveguide biosensor

S^1 \times S^2 as a bag membrane and its Einstein-Weyl geometry

In the hybrid skyrmion in which an Anti-de Sitter bag is imbedded into the skyrmion configuration a S^{1}\times S^{2} membrane is lying on the compactified spatial infinity of the bag [H. Rosu, Nuovo Cimento B 108, 313 (1993)]. The connection between the quark degrees of freedom and the mesonic ones is made through the membrane, in a way that should still be clarified from the standpoint of general relativity and topology. The S^1 \times S^2 membrane as a 3-dimensional manifold is at the same time a Weyl-Einstein space. We make here an excursion through the mathematical body of knowledge in the differential geometry and topology of these spaces which is expected to be useful for hadronic membranesComment: 9pp in latex, minor correction

Sensitivity of the g-mode frequencies to pulsation codes and their parameters

From the recent work of the Evolution and Seismic Tools Activity (ESTA, Lebreton et al. 2006; Monteiro et al. 2008), whose Task 2 is devoted to compare pulsational frequencies computed using most of the pulsational codes available in the asteroseismic community, the dependence of the theoretical frequencies with non-physical choices is now quite well fixed. To ensure that the accuracy of the computed frequencies is of the same order of magnitude or better than the observational errors, some requirements in the equilibrium models and the numerical resolutions of the pulsational equations must be followed. In particular, we have verified the numerical accuracy obtained with the Saclay seismic model, which is used to study the solar g-mode region (60 to 140$\mu$Hz). We have compared the results coming from the Aarhus adiabatic pulsation code (ADIPLS), with the frequencies computed with the Granada Code (GraCo) taking into account several possible choices. We have concluded that the present equilibrium models and the use of the Richardson extrapolation ensure an accuracy of the order of $0.01 \mu Hz$ in the determination of the frequencies, which is quite enough for our purposes.Comment: 10 pages, 5 figures, accepted in Solar Physic

Solar Neutrino Oscillation Diagnostics at Superkamiokande and Sno

Results for solar neutrino detection from the SuperKamiokande collaboration have been presented recently while those from the Sudbury Neutrino Observatory are expected in the near future. These experiments are sensitive to the 8B neutrinos from the sun, the shape of whose spectrum is well-known but the normalisation is less certain. We propose several variables, insensitive to the absolute flux of the incident beam, which probe the shape of the observed spectrum and can sensitively signal neutrino oscillations. They provide methods to extract the neutrino mixing angle and mass splitting from the data and also to distinguish oscillation to sequential neutrinos from those to a sterile neutrino.Comment: 11 pages Latex, 2 figure