23 research outputs found
The Role of Passenger Leukocytes in Rejection and “Tolerance” after Solid Organ Transplantation: A Potential Explanation of a Paradox
Full text linkInterleukin-10 induces the upregulation of the inhibitory receptor ILT4 in monocytes from HIV positive individuals
No full textRole of the indirect recognition pathway in the development of chronic liver allograft rejection
No full textPresence of HLA-Class I specific T suppressor (Ts) cells in kidney allograft recipients.
No full textVolume 54,Supplemento 1, July/August 2001, Scandinavian Journal of Immunology
KIDNEY ALLOGRAFT RECIPIENTS DEVELOP HLA-CLASS I SPECIFIC T SUPPRESSOR CELLS
No full textmeritevole di un 2000 ERA-EDTA Congress Gran
ORGAN ALLOGRAFT RECIPIENTS DEVELOP HLA CLASS I-SPECIFIC T SUPPRESSOR CELLS
No full textALTHOUGH THE mechanism of organ allograft rejection
has been extensively studied, little is currently
known about the regulatory T cells that can maintain the
state of quiescence. Recent evidence indicates that T
suppressor cells (Ts) can be generated in vitro by multiple
allostimulation of CD81CD282 T cells with allogeneic
APC. Ts were shown to recognize HLA class I alloantigens
on target APC and inhibit their ability to provide costimulatory
signals to Th, blocking transcription of CD80, CD86,
and CD40 molecules. We have explored the possibility that
allospecific CD81CD282 Ts down-regulate the immune
response against the graft.1–
