ANALYSIS OF INTERACTION OF QUALITY POISONING AND QUANTITY INDICES ON THE BACKGROUND OF ETHANOL ALCOHOLIC LIVER DISEASE

We studied the correlation between quantitative and qualitative-governmental indicators for poisoning with ethanol on a background of alcoholic liver disease (110 cases). The positive and negative relation between the varying degree of alcohol content in the departments of venous and alkogolokislyayuschih activity of enzyme systems (AOFS) level alkogolemii and necro-inflammatory processes in the liver, morphological manifestations of poisoning with ethanol and the state AOFS. Revealed high negative correlation between the diameter of the portal vein, the number of blood vessels of medium caliber and the development of fibrosis

PATOMORFOLOGICHESKY ASSESSMENT ETHANOL POISONING AMID ALCOHOLIC LIVER DISEASE

Morphological pattern of alcohol poisoning and its evaluation remains controversial issue to date. In this paper we analyzed and evaluated pathologic features ethanol intoxication in patients with various forms of alcoholic liver disease (ALD)

THE DIAGNOSIS AND TREATMENT OF PRIMARY PULMONARY HYPERTENSION: A MODERN VIEW ON THE PROBLEM

There are basic principles of diagnostics and treatment of patients with the primary pulmonary hypertension - Aersy desease. Clinical examples of this pathology, illustration of an echocardiology

Death from the introduction of Ceftriaxone in the presence of Lidocaine (case report)

In clinical and expert practice, pathological processes such as toxic reactions and anaphylaxis may develop following the introduction of the local anesthetic lidocaine; however, information about the death of children is limited and scattered. The morphological signs of these cases are non-specific, which leads to difficulty in interpreting the results of the study and determining the causes of death. This report described the death of a child following intramuscular administration of ceftriaxone in a 2% lidocaine solution. The results of the primary and commission examination of the corpse and data of repeated pathohistological examinations of a 2-year-old child are presented. The objective expert conclusion about the cause of death following the intramuscular administration of ceftriaxone in a 2% lidocaine solution was toxic effects (overdose) or anaphylactic shock, which requires assessing the sequence of the event and nature of the clinical picture, taking into account the route of drug administration, comprehensive pathohistological and morphological studies, and mandatory forensic chemical determination of the concentration of these drugs in the internal organs and blood. Morphological signs of an allergic reaction can be verified based on pathomorphological data, including changes in the target organs of anaphylaxis and pronounced hemocirculatory disorders. In our opinion, further in-depth study and systematization of available data are needed

The case of myocardial infarction the young woman through 6 months after childbirth

The article presents the main reasons for the development of myocardial infarction of young women. We gave a clinical example of this disease the young woman 29 years old through 6 months after childbirth

Liver pathologies in the structure of deaths from gastrointestinal diseases in Krasnodar Krai in 2014–2018

Aim. To determine the frequency of liver pathologies among the causes of death from gastrointestinal diseases in Krasnodar Krai in 2014–2018.Materials and methods. The prevalence of liver pathologies in the structure of deaths from gastrointestinal diseases was studied according to the annual reports of the Bureau of Forensic Medical Examination of the Ministry of Health of Krasnodar Krai (FME Bureau), medical certificates of death (form No. 106/U-08) issued by forensic experts and registered in the mortality monitoring database (Parus information system), and data obtained from the Medical Information Analytical Centre of Krasnodar Krai for 2014-2018.Results. Liver pathologies account for more than 50% cases in the structure of mortality from gastrointestinal diseases. More frequently, this reason caused death in 50–60 year old men and 60–65 year old women. Liver pathologies were found mainly in urban residents. It is noteworthy that, in the studied period, such deaths most frequently occurred at home, on the street, in public transport, etc.; only about 15% of patients died in hospitals. Among the registered liver diseases leading to death (ICD 10, headings K70–K77), cirrhosis of various etiologies was the leading cause, with “unspecified cirrhosis” being ranked the first place. Over the studied period, this cause of death showed a growing trend. Thus, 67.12%, 74.59%, 89.58% and 85.12% of such cases were registered in 2015, 2016, 2017 and 2018, respectively. In 2014–2016, cirrhosis and liver fibrosis (code K74), and alcoholic cirrhosis (code K70.3) were ranked the 2nd and 3rd more frequent death cause, respectively. Since 2017, alcoholic cirrhosis of the liver has occupied the 2nd place. However, over the 2014–2018 period, a decrease in the frequency of cirrhosis of alcoholic etiology was noted: its share was 10.52% of all cirrhosis in 2015, decreasing to 10.17%, 6.59%, 4.86% and 4.39% in 2015, 2016, 2017 and 2018, respectively.Conclusion. Although mortality due to gastrointestinal diseases continues to decrease, liver pathologies remain to be the leading cause in 50% of such deaths. The leading disease is cirrhosis and unspecified liver fibrosis. According to the FME Bureau, deaths from cirrhosis occur outside hospitals in more than 85% of cases. The absence of cirrhosis verification by the etiological factor during autopsy requires the development of an algorithm of action, which should include a full-fledged investigation of the corpse, subsequent histological examination, assessment of pathomorphological signs taking into account clinical and medical history data and exclusion of the viral process by conducting serological tests

ORGANIZATION OF TREATMENT OF CHILDREN WITH SPASTIC FORMS OF CEREBRAL PALSY BY BOTULINUM TOXIN TYPE A IN KRASNODAR REGION

This article presents the organizacion of treatment for children with cerebral palsy with the botulinum toxin type A in large children’s therapeutic and prophylactic institutions in Krasnodar region. Such organization allows to cover the treatment of about 20 % of children with spastic forms of cerebral palsy, to ensure the purity of performance technique and to provide adequate rehabilitation

TO PEDIATRIC FACULTY OF THE KUBAN STATE MEDICAL UNIVERSITY – 45 YEARS

This article is dedicated to the 45th pediatric department's anniversary of the Kuban state medical university. It reflects the history and prospects for further development of the faculty. Each department of pediatric faculty cherishes its traditions and history