Anthelmintic activity of nanoencapsulated carvacryl acetate against gastrointestinal nematodes of sheep and its toxicity in rodents.

Abstract: The objective of this study was to evaluate the efficacy of carvacryl acetate (CVA) and nanoencapsulated CVA (nCVA) on gastrointestinal nematodes of sheep. The CVA was nanoencapsulated with chitosan/gum arabic and the efficacy of nanoencapsulation (EE), yield, zeta potential, nanoparticle morphology and release kinetics at pH 3 and 8 were analyzed. Acute and subchronic toxicity were evaluated in rodents and reduction of egg counts in the faeces (FECRT) of sheep. The sheep were divided into four groups (n = 10): G1, 250 mg/kg CVA; G2, 250 mg/kg nCVA; G3, polymer matrix and G4: 2.5 mg/kg monepantel. EE and nCVA yield were 65% and 57%, respectively. The morphology of the nanoparticles was spherical, size (810.6±286.7 nm), zeta potential in pH 3.2 (+18.3 mV) and the 50% release of CVA at pHs 3 and 8 occurred at 200 and 10 h, respectively. nCVA showed LD50 of 2,609 mg/kg. CVA, nCVA and monepantel reduced the number of eggs per gram of faeces (epg) by 57.7%, 51.1% and 97.7%, respectively. The epg of sheep treated with CVA and nCVA did not differ from the negative control (P>0.05). Nanoencapsulation reduced the toxicity of CVA; however, nCVA and CVA presented similar results in the FECRT. [Atividade anti-helmíntica do acetato de carvacrila nanoencapsulado sobre nematoides gastrintestinais de ovinos e toxicidade em roedores]. Resumo: O objetivo deste trabalho foi avaliar a eficácia do acetato de carvacrila (ACV) e do ACV nanoencapsulado (nACV) sobre nematóides gastrintestinais de ovinos. O ACV foi nanoencapsulado com quitosana/goma arábica e foi analisada a eficácia de nanoencapsulamento (EE), o rendimento, potencial zeta, morfologia das nanopartículas e cinética de liberação em pH 3 e 8. Foram avaliadas as toxicidades aguda e subcrônica em roedores e a redução da contagem de ovos nas fezes (RCOF) de ovinos. Os ovinos foram divididos em quatro grupos (n = 10): G1, 250 mg/kg ACV; G2, 250 mg/kg de nACV; G3, matriz polimérica e G4: 2,5 mg/kg de monepantel. A EE e o rendimento de nACV foram de 65% e 57%, respectivamente. A morfologia das nanopartículas foi esférica, tamanho (810,6±286,7 nm), potencial zeta no pH 3,2 (+18,3 mV) e a liberação de 50% de CVA nos pHs 3 e 8 ocorreu às 200 e 10 h, respectivamente. nACV apresentou DL50 de 2.609 mg/kg. ACV, nACV e o monepantel reduziram a contagem de ovos por grama de fezes (opg) em 57,7%, 51,1% e 97,7%, respectivamente. A contagem de opg de ovelhas tratadas com ACV e nCVA não diferiu do controle negativo (P>0,05). O nanoencapsulamento reduziu a toxicidade do AVC; no entanto, nACV e ACV apresentaram resultados semelhantes na RCOF

Critical temperature of a fully anisotropic three-dimensional Ising model

The critical temperature of a three-dimensional Ising model on a simple cubic lattice with different coupling strengths along all three spatial directions is calculated via the transfer matrix method and a finite size scaling for L x L oo clusters (L=2 and 3). The results obtained are compared with available calculations. An exact analytical solution is found for the 2 x 2 oo Ising chain with fully anisotropic interactions (arbitrary J_x, J_y and J_z).Comment: 17 pages in tex using preprint.sty for IOP journals, no figure

Theory of ultracold Fermi gases

The physics of quantum degenerate Fermi gases in uniform as well as in harmonically trapped configurations is reviewed from a theoretical perspective. Emphasis is given to the effect of interactions which play a crucial role, bringing the gas into a superfluid phase at low temperature. In these dilute systems interactions are characterized by a single parameter, the s-wave scattering length, whose value can be tuned using an external magnetic field near a Feshbach resonance. The BCS limit of ordinary Fermi superfluidity, the Bose-Einstein condensation (BEC) of dimers and the unitary limit of large scattering length are important regimes exhibited by interacting Fermi gases. In particular the BEC and the unitary regimes are characterized by a high value of the superfluid critical temperature, of the order of the Fermi temperature. Different physical properties are discussed, including the density profiles and the energy of the ground-state configurations, the momentum distribution, the fraction of condensed pairs, collective oscillations and pair breaking effects, the expansion of the gas, the main thermodynamic properties, the behavior in the presence of optical lattices and the signatures of superfluidity, such as the existence of quantized vortices, the quenching of the moment of inertia and the consequences of spin polarization. Various theoretical approaches are considered, ranging from the mean-field description of the BCS-BEC crossover to non-perturbative methods based on quantum Monte Carlo techniques. A major goal of the review is to compare the theoretical predictions with the available experimental results.Comment: Revised and abridged version accepted for publication in Rev. Mod. Phys.: 63 pages, 36 figure

Performance produtiva de cultivares de milho na região Nordeste do Brasil, na safra 2006/2007.

bitstream/item/80668/1/boletim-78.PD

Electron and Hole Spin Splitting and Photogalvanic Effect in Quantum Wells

A theory of the circular photogalvanic effect caused by spin splitting in quantum wells is developed. Direct interband transitions between the hole and electron size-quantized subbands are considered. It is shown that the photocurrent value and direction depend strongly on the form of the spin-orbit interaction. The currents induced by structure-, bulk-, and interface-inversion asymmetry are investigated. The photocurrent excitation spectra caused by spin splittings in both conduction and valence bands are calculated.Comment: 7 pages, 3 figure

Renormalization Group Study of Chern-Simons Field Coupled to Scalar Matter in a Modified BPHZ Subtraction Scheme

We apply a soft version of the BPHZ subtraction scheme to the computation of two-loop corrections from an Abelian Chern-Simons field coupled to (massive) scalar matter with a $\lambda(\Phi^\dag\Phi)^2$ and $\nu(\Phi^\dag\Phi)^3$ self-interactions. The two-loop renormalization group functions are calculated. We compare our results with those in the literature.Comment: 15 pages, 7 figures, revtex. To appear in Phys. Rev.

Avaliação da qualidade comercial dos grãos de linhagens de feijoeiro-comum carioca com ciclo precoce.

O objetivo desse trabalho foi identificar linhagens precoces de feijoeiro-comum de grãos tipo carioca com alta produtividade de grãos, porcentagem de grãos com tamanho comercial e massa de cem grãos.CONAF