3,159 research outputs found
The effect of tumour necrosis factor-alpha and insulin on equine digital blood vessel function in vitro
Emergence of Fermi pockets in an excitonic CDW melted novel superconductor
A superconducting (SC) state (Tc ~ 4.2K) has very recently been observed upon
successful doping of the CDW ordered triangular lattice TiSe, with copper.
Using high resolution photoemission spectroscopy we identify, for the first
time, the momentum space locations of the doped electrons that form the Fermi
sea of the parent superconductor. With doping, we find that the kinematic
nesting volume increases whereas the coherence of the CDW order sharply drops.
In the superconducting doping, we observe the emergence of a large density of
states in the form of a narrow electron pocket near the \textit{L}-point of the
Brillouin Zone with \textit{d}-like character. The \textit{k}-space electron
distributions highlight the unconventional interplay of CDW to SC cross-over
achieved through non-magnetic copper doping.Comment: 4+ pages, 5 figures; Accepted for publication in Phys. Rev. Lett.
(2007
Fermi surface topology and low-lying quasiparticle structure of magnetically ordered Fe1+xTe
We report the first photoemission study of Fe1+xTe - the host compound of the
newly discovered iron-chalcogenide superconductors. Our results reveal a pair
of nearly electron- hole compensated Fermi pockets, strong Fermi velocity
renormalization and an absence of a spin-density-wave gap. A shadow hole pocket
is observed at the "X"-point of the Brillouin zone which is consistent with a
long-range ordered magneto-structural groundstate. No signature of Fermi
surface nesting instability associated with Q= pi(1/2, 1/2) is observed. Our
results collectively reveal that the Fe1+xTe series is dramatically different
from the undoped phases of the high Tc pnictides and likely harbor unusual
mechanism for superconductivity and quantum magnetic order.Comment: 5 pages, 4 Figures; Submitted to Phys. Rev. Lett. (2009
Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration
Tau protein inclusions are a frequent hallmark of a variety of neurodegenerative disorders. The 10+16 intronic mutation in MAPT gene, encoding tau, causes frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17), by altering the splicing of the gene and inducing an increase in the production of 4R tau isoforms, which are more prone to aggregation. However, the molecular mechanisms linking increased 4R tau to neurodegeneration are not well understood. Here, we have used iPSC-derived neurons from patients of FTDP-17 carrying the 10+16 mutation to study the molecular mechanisms underlying neurodegeneration. We show that mitochondrial function is altered in the neurons of the patients. We found that FTDP-17 neurons present an increased mitochondrial membrane potential, which is partially maintained by the F1Fo ATPase working in reverse mode. The 10+16 MAPT mutation is also associated with lower mitochondrial NADH levels, partially supressed complex I-driven respiration, and lower ATP production by oxidative phosphorylation, with cells relying on glycolysis to maintain ATP levels. Increased mitochondrial membrane potential in FTDP-17 neurons leads to overproduction of the ROS in mitochondria, which in turn causes oxidative stress and cell death. Mitochondrial ROS overproduction in these cells is a major trigger for neuronal cell death and can be prevented by mitochondrial antioxidants
Complete d-Band Dispersion and the Mobile Fermion Scale in NaxCoO2
We utilize fine-tuned polarization selection coupled with excitation-energy
variation of photoelectron signal to image the \textit{complete d}-band
dispersion relation in sodium cobaltates. A hybridization gap anticrossing is
observed along the Brillouin zone corner and the full quasiparticle band is
found to emerge as a many-body entity lacking a pure orbital polarization. At
low dopings, the quasiparticle bandwidth (Fermion scale, many-body
\textit{E} 0.25 eV) is found to be smaller than most known oxide
metals. The low-lying density of states is found to be in agreement with
bulk-sensitive thermodynamic measurements for nonmagnetic dopings where the 2D
Luttinger theorem is also observed to be satisfied.Comment: 4+ pages, 5 Fig
Low-lying quasiparticle states and hidden collective charge instabilities in parent cobaltate superconductors (NaxCoO2)
We report a state-of-the-art photoemission (ARPES) study of high quality
single crystals of the NaxCoO2 series focusing on the fine details of the
low-energy states. The Fermi velocity is found to be small (< 0.5 eV.A) and
only weakly anisotropic over the Fermi surface at all dopings setting the size
of the pair wavefunction to be on the order of 10-20 nanometers. In the low
doping regime the exchange inter-layer splitting vanishes and two dimensional
collective instabilities such as 120-type fluctuations become kinematically
allowed. Our results suggest that the unusually small Fermi velocity and the
unique symmetry of kinematic instabilities distinguish cobaltates from other
unconventional oxide superconductors such as the cuprates or the ruthenates.Comment: Accepted for publication in Phys. Rev. Lett. (2006
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