Vineyard weed flora in the Jastrebarsko area (NW Croatia)

Vineyard weed flora was surveyed over the wider Jastrebarsko area (a part of Ple{ivica Mountain, north-west part of Croatia), a well known wine-growing area. The survey was carried out in the years 2001 and 2002, in ten vineyards at six different localities. Ahundred and nine (109) weed species were noted. The presence of segetal weeds such as Amaranthus retroflexus L., Chenopodium album L., Stellaria media (L.)Vill. was recorded in well cultivated vineyards. In addition, ruderal weed species such as Ambrosia artemisiifolia L. were found in vineyards, coming in from surrounding habitats. The species Arctium lappa L., Artemisia vulgaris L. and the others prevail in neglected and abandoned vineyards. It is interesting to record findings of Amaranthus retroflexus, Artemisia vulgaris, Capsella bursa – pastoris (L.)Med. and Daucus carota L. because these species have result in bad grape and wine quality

Classification and Performance Evaluation of Instruction Buffering Techniques

The speed disparity between processor and memory subsystems has been bridged in many existing large-scale scientific computers and microprocessors with the help of instruction buffers or instruction caches. In this paper we classify these buffers into traditional instruction buffers, conventional instruction caches and prefetch queues, detail their prominent features, and evaluate the performance of buffers in several existing systems, using trace driven simulation. We compare these schemes with a recently proposed queue-based instruction cache memory. An implementation independent performance metric is proposed for the various organizations and used for the evaluations. We analyze the simulation results and discuss the effect of various parameters such as prefetch threshold, bus width and buffer size on performance

Late Upper Paleolithic, Early Mesolithic and Early Neolithic from the cave site Zemunica near Bisko (Dalmatia, Croatia)

This paper presents results from lithic, pottery, zooarchaeological, osteological, petrological and geoarcheological analyses from the Early Neolithic, Mesolithic and late Upper Paleolithic levels of Zemunica Cave in Croatia. The site provides valuable information about the aforementioned periods in Dalmatia and original evidence supporting newly proposed models of the spread of Neolithisation in this area

Profiling colorectal cancer in the landscape personalized testing—advantages of liquid biopsy

Drug‐specific therapeutic approaches for colorectal cancer (CRC) have contributed to significant improvements in patient health. Nevertheless, there is still a great need to improve the personalization of treatments based on genetic and epigenetic tumor profiles to maximize the quality and efficacy while limiting cytotoxicity. Currently, CEA and CA 19‐9 are the only validated blood biomarkers in clinical practice. For this reason, laboratories are trying to identify new specific prognostics and, more importantly, predictive biomarkers for CRC patient profiling. Thus, the unique landscape of personalized biomarker data should have a clinical impact on CRC treatment strategies and molecular genetic screening tests should become the standard method for diagnosing CRC. This review concentrates on recent molecular testing in CRC and discusses the potential modifications in CRC assay methodology with the upcoming clinical application of novel genomic approaches. While mechanisms for analyzing circulating tumor DNA have been proven too inaccurate, detecting and analyzing circulating tumor cells and protein analysis of exosomes represent more promising options. Blood liquid biopsy offers good prospects for the future if the results align with pathologists’ tissue analyses. Overall, early detection, accurate diagnosis and treatment monitoring for CRC with specific markers and targeted molecular testing may benefit many patients

Aquatic and Wetland Vegetation Along the Sava River

Diverse hydrological, climate, and soil conditions along the Sava River caused significant diversification of vegetation. Therefore, the objective of this chapter is to integrate and present all the available data on variability of the aquatic and riparian plant communities along the Sava River and its main tributaries as well as to identify the environmental factors, which are related to the distribution of different vegetation types. Special attention has been also paid on the detection of threats for rare and endangered plant species and fragile wetland ecosystems along the Sava River. Based on data review, syntaxonomic revision of aquatic and riparian vegetation based on common, pan-European databank is required. Ecological studies that involve inventory, monitoring, modeling, and prediction of changes in populations, ecological communities, and ecosystems require both georeferenced databases and computational tools for application of statistical methods.Milačič R, Ščančar J, Paunović M, editors. The Sava River. Berlin, Heidelberg: Springer-Verlag; 2015. p. 249-316