10 research outputs found
Dietary lipid-dependent regulation of de novo lipogenesis and lipid partitioning by ketogenic essential amino acids in mice
Get PDFAn innovative antilithogenic beverage HydroZitLa inhibits stone formation in experimental nephrolithiasis rats and extends lifespan in C. elegans worms
No full textRôle de l’AMPK, mTOR et GCN2 dans la détection des AA dans des hépatocytes en culture primaire
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A recombinant antigen-based lgG4 ELSA for the specific and sensitive detection of Brugia malayi infection
No full textAn IgG4 ELISA based on a novel recombinant antigen was evaluated for detection of Brugia malayi
infection, using 2487 sera from various institutions: 2031 samples from Universiti Sains Malaysia, 276
blinded sera from 2 other institutions in Malaysia, 140 blinded sera from India and 40 blinded sera from
Thailand. These sera were from various groups of individuals, i.e., microfilaraemics, chronic patients,
endemic normals, non-endemic normals and individuals with other parasitic and bacterial infections. Based
on a cut-off optical density reading of 0.300, the IgG4 ELISA demonstrated specificity rates of 95.6- l00%,
sensitivity rates of 96- l00%, positive predictive values of 75- 100% and negative predictive values of 98.9-
100%. These evaluation studies demonstrated the high specificity and sensitivity of this test for the detection
of active B. malayi infection. Thus, the IgG4 ELISA would be very useful as a tool in diagnosis and in
elimination programmes for brugian filariasis
N-3 fatty acids improve body composition and insulin sensitivity during energy restriction in the rat
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