Using earcons to improve the usability of tool palettes

This paper describes an experiment to investigate the effectiveness of adding sound to tool palettes. Palette shave usability problems because users need to see the information they present but they are often outside the area of visual focus. Non-speech sounds called earcons were used to indicate the current tool and tool changes so that users could tell what tool was in use, wherever they were looking. Experimental results showed a significant reduction in the number of tasks performed with the wrong tool. Users knew what the current tool was and did not try to perform tasks with the wrong one

Haptic feedback in the training of veterinary students

This paper reports on an initial study into the use of haptic (or touch) technology in the training of veterinary students. One major problem faced in veterinary education is that animals can be harmed by inexperienced students who are trying to learn the skills they need. The aim of the work described here is to provide haptic models to simulate internal examinations of horses so that students can learn the basic skills required on computer and then transfer to real animals with much less risk of doing them injury

Variations in the propagation of UH-nuclei

Calculations of the propagation of UH-nuclei were improved by extending the number of individual nuclides considered, and by using more recent evaluations of the rigidity dependence of the escape length, the possible source composition, and altered cross sections. The effects of using different expressions for the dependence of abundances on first ionization potentials (FIP) are outlined. The sensitivity of the calculated elemental abundances to the various changes made in the propagation assumptions are discussed

Azimuth axis optical alignment system Final report

Azimuth axis optical alignment system to monitor and measure attitude or angular position of remote object about azimuth axis using phase information imposed on returning beam of ligh

Halomethyl-Triazoles for Rapid, Site-Selective Protein Modification

Post-translational modifications (PTMs) are used by organisms to control protein structure and function after protein translation, but their study is complicated and their roles are not often well understood as PTMs are difficult to introduce onto proteins selectively. Designing reagents that are both good mimics of PTMs, but also only modify select amino acid residues in proteins is challenging. Frequently, both a chemical warhead and linker are used, creating a product that is a misrepresentation of the natural modification. We have previously shown that biotin-chloromethyl-triazole is an effective reagent for cysteine modification to give S-Lys derivatives where the triazole is a good mimic of natural lysine acylation. Here, we demonstrate both how the reactivity of the alkylating reagents can be increased and how the range of triazole PTM mimics can be expanded. These new iodomethyl-triazole reagents are able to modify a cysteine residue on a histone protein with excellent selectivity in 30 min to give PTM mimics of acylated lysine side-chains. Studies on the more complicated, folded protein SCP-2L showed promising reactivity, but also suggested the halomethyl-triazoles are potent alkylators of methionine residues

Human resource management: the promise, the performance, the consequences

Purpose – The dominant focus of HRM research has been that of “strategic HRM”, that is a focus on the impact of HRM on firm performance. The authors argue that not only are the cumulative results of this “dominant research orthodoxy” disappointing in terms of their external validity, but also they are of limited practical value. Further, it has failed not only in terms of its narrow firm performance-oriented agenda, but also the tenets of its agenda have contributed to serious levels of employee dissatisfaction and to the failure to deal with pressing global issues. The paper aims to discuss these issues. Design/methodology/approach – In order to assess the contribution of the dominant research orthodoxy the authors analyse the 16 most cited journal articles in the field of HRM. Findings – The authors find a predominance of US-centric studies and therefore a questionable cross-national generalizability of the dominant research orthodoxy. The use of cross-sectional data means that long-term effects cannot be gauged. The authors observe a lack of consensus on how to operationalize HRM and firm performance. National context is generally absent. Practical implications – The authors show that for HRM to realize its potential for governments, media, or philanthropic agencies, HRM must abandon its restricted scope and mono-dimensional sources of inspiration. Originality/value – The authors not only point to the shortcomings of the dominant research orthodoxy within HRM, but the authors point to how HRM could become significantly more “centre-staged” by addressing the actors searching for contributions to the big questions of the world – the governments, media, and philanthropic agencies

What disability? I am a leader! Understanding leadership in HE from a disability perspective

This article is based on the findings of an externally funded, mixed-methods research project conducted at one English university. This small-scale project aimed to examine leadership, barriers to becoming a leader and the support needed to overcome them, from the perspectives of disabled staff. An online questionnaire was sent to all 66 members of staff who had disclosed their disabled status to the university and 22 responses were received. Twelve participants were then interviewed as two focus groups to discuss their views on leadership and its relation to their role. Six more respondents opted for individual face-to-face/telephone interviews. The findings indicated that over half of the respondents were already engaged in ‘formal’ leadership and even more exercised ‘informal’ leadership. This key finding seems to contradict the under-representation of disabled academics in leadership reported in the literature. Despite their engagement in leadership, disabled staff faced several institutional and personal barriers. The findings suggest that having an impairment per se might not necessarily deter disabled staff from exercising leadership. A number of support strategies are recommended to facilitate their participation in (formal) leadership

Navigating Telephone-Based Interfaces with Earcons

Non-speech audio messages called earcons can provide powerful navigation cues in menu hierarchies. However, previous research on earcons has not addressed the particular problems of menus in telephone-based interfaces (TBI's) such as: Does the lower quality of sound in TBI's lower recall rates, can users remember earcons over a period of time and what effect does training type have on recall. An experiment was conducted and results showed that sound quality did lower the recall of earcons. However, redisgn of the earcons overcame this problem with 73 % recalled correctly. Participants could still recall earcons at this level after a week had passed. Training type also affected recall. With 'personal training' participants recalled 73% of the earcons but with purely textual training results were significantly lower. These results show that earcons can provide excellent navigation cues for telephone-based interface

Calciphylaxis following kidney transplantation: a case report

Introduction: Calciphylaxis occurring after kidney transplantation is rare and rarely reported. It results in chronic non-healing wounds and is associated with a poor prognosis and is often fatal. We present a case of proximal lower limb calciphylaxis that occurred early after kidney transplantation. The patient had no classic associated risk factors. He had previously had a total parathyroidectomy but had normal serum calcium-phosphate product and parathyroid hormone levels. The clinical outcome of this case was favorable and highlights some fundamental issues relating to management. Case prsentation: A 70-year-old British Caucasian man with end-stage renal failure secondary to IgA nephropathy presented six months post kidney transplantation with cutaneous calciphylaxis lesions involving the medial aspect of the thigh bilaterally. Conclusion: To the best of our knowledge, this is the first reported case of rapid onset cutaneous calciphylaxis occurring soon after kidney transplantation that was associated with a favorable outcome. Cutaneous calciphylaxis lesions should be promptly managed with meticulous wound care, antimicrobial therapy and the correction of calcium-phosphate product where indicated