22,998 research outputs found

    Psychotherapy and social support - Integrating research on psychological helping

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    Psychotherapy interactions and social support conversations have many similarities, as well as some important differences. Researchers studying these two manifestations of psychological helping - often known as formal and informal helping - usually apply a separate set of concepts and methods to each and tend to locate their work in separate bodies of literature. This paper argues that such a division of the field is unnecessary and unproductive. It outlines several ways in which the two bodies of literature might inform each other and argues for conceptual integration of the two fields. (C) 2001 Elsevier Science Ltd. All rights reserved

    Vibrophonocardiograph Patent

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    Vibrophonocardiograph comprising low weight and small volume piezoelectric microphone with amplifier having high imput impedance for high sensitivity and low frequency respons

    Mutual help groups for mental health problems: A review of effectiveness studies

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    This paper reviews empirical studies on whether participating in mutual help groups for people with mental health problems leads to improved psychological and social functioning. To be included, studies had to satisfy four sets of criteria, covering: (1) characteristics of the group, (2) target problems, (3) outcome measures, and (4) research design. The 12 studies meeting these criteria provide limited but promising evidence that mutual help groups benefit people with three types of problems: chronic mental illness, depression/anxiety, and bereavement. Seven studies reported positive changes for those attending support groups. The strongest findings come from two randomized trials showing that the outcomes of mutual help groups were equivalent to those of substantially more costly professional interventions. Five of the 12 studies found no differences in mental health outcomes between mutual help group members and non-members; no studies showed evidence of negative effects. There was no indication that mutual help groups were differentially effective for certain types of problems. The studies varied in terms of design quality and reporting of results. More high-quality outcome research is needed to evaluate the effectiveness of mutual help groups across the spectrum of mental health problems

    Localization of the Functional Domains of Human Tissue Inhibitor of Metalloproteinases-3 and the Effects of a Sorsby's Fundus Dystrophy Mutation

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    A transient COS-7 cell expression system was used to investigate the functional domain arrangement of tissue inhibitor of metalloproteinases-3 (TIMP-3), specifically to assess the contribution of the amino- and carboxylterminal domains of the molecule to its matrix metalloproteinase (MMP) inhibitory and extracellular matrix (ECM) binding properties. Wild type TIMP-3 was entirely localized to the ECM in both its glycosylated (27 kDa) and unglycosylated (24 kDa) forms. A COOH-terminally truncated TIMP-3 molecule was found to be a non- ECM bound MMP inhibitor, whereas a chimeric TIMP molecule, consisting of the NH2-terminal domain of TIMP-2 fused to the COOH-terminal domain of TIMP-3, displayed ECM binding, albeit with a lower affinity than the wild type TIMP-3 molecule. Thus the functional domain arrangement of TIMP-3 is analogous to that seen in TIMP-1 and -2, namely that the NH2-terminal domain is responsible for MMP inhibition whereas the COOH-terminal domain is most important in mediating the specific functions of the molecule. A mutant TIMP-3 in which serine 181 was changed to a cysteine, found in Sorsby’s fundus dystrophy, a hereditary macular degenerative disease, was also expressed in COS-7 cells. This gave rise to an additional 48-kDa species (possibly a TIMP-3 dimer) that retained its ability to inhibit MMPs and localize to the ECM. These data favor the hypothesis that the TIMP-3 mutations seen in Sorsby’s fundus dystrophy contribute to disease progression by accumulation of mutant protein rather than by the loss of functional TIMP-3

    Super-resolution imaging of a low frequency levitated oscillator

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    We describe the measurement of the secular motion of a levitated nanoparticle in a Paul trap with a CMOS camera. This simple method enables us to reach signal-to-noise ratios as good as 106^{6} with a displacement sensitivity better than 10−16 m2^{-16}\,m^{2}/Hz. This method can be used to extract trap parameters as well as the properties of the levitated particles. We demonstrate continuous monitoring of the particle dynamics on timescales of the order of weeks. We show that by using the improvement given by super-resolution imaging, a significant reduction in the noise floor can be attained, with an increase in the bandwidth of the force sensitivity. This approach represents a competitive alternative to standard optical detection for a range of low frequency oscillators where low optical powers are require

    Analytical simulation of the Langley Research Center integrated life-support system, volume 1

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    Analytical simulation of integrated life support system and oxygen recovery syste

    Exploiting correlogram structure for robust speech recognition with multiple speech sources

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    This paper addresses the problem of separating and recognising speech in a monaural acoustic mixture with the presence of competing speech sources. The proposed system treats sound source separation and speech recognition as tightly coupled processes. In the first stage sound source separation is performed in the correlogram domain. For periodic sounds, the correlogram exhibits symmetric tree-like structures whose stems are located on the delay that corresponds to multiple pitch periods. These pitch-related structures are exploited in the study to group spectral components at each time frame. Local pitch estimates are then computed for each spectral group and are used to form simultaneous pitch tracks for temporal integration. These processes segregate a spectral representation of the acoustic mixture into several time-frequency regions such that the energy in each region is likely to have originated from a single periodic sound source. The identified time-frequency regions, together with the spectral representation, are employed by a `speech fragment decoder' which employs `missing data' techniques with clean speech models to simultaneously search for the acoustic evidence that best matches model sequences. The paper presents evaluations based on artificially mixed simultaneous speech utterances. A coherence-measuring experiment is first reported which quantifies the consistency of the identified fragments with a single source. The system is then evaluated in a speech recognition task and compared to a conventional fragment generation approach. Results show that the proposed system produces more coherent fragments over different conditions, which results in significantly better recognition accuracy

    ‘It’s a tiger instinct – that’s my baby!’: affective practices of care in parents’ educational activism

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    This article presents findings from a qualitative study exploring parents’ struggles over their children’s education. Drawing on affective practice theory (Wetherell, 2012) and feminist care ethics (Fisher and Tronto 1990), we offer insights into the affective practices of care driving parents’ educational activism. We detail how parents’ activism is rooted in powerful feelings of responsibility for their own children as well as more altruistic concerns. Whilst ostensibly grounded in self-interest, we argue that parents’ activism challenges the traditional binary between altruism and self-interest, indicating instead that they can be mutually constitutive of collective action; a complex form of affective practice we designate altruistic self-interest. Our analysis suggests parental activism can be a force for progressive educational change in which care for intimates and care for others coincide, but also that educational authorities could adopt a more care-full approach when making key decisions affecting children, families and communities

    The 8^8B Neutrino Spectrum

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    Knowledge of the energy spectrum of 8^8B neutrinos is an important ingredient for interpreting experiments that detect energetic neutrinos from the Sun. The neutrino spectrum deviates from the allowed approximation because of the broad alpha-unstable 8^8Be final state and recoil order corrections to the beta decay. We have measured the total energy of the alpha particles emitted following the beta decay of 8^8B. The measured spectrum is inconsistent with some previous measurements, in particular with a recent experiment of comparable precision. The beta decay strength function for the transition from 8^8B to the accessible excitation energies in 8^8Be is fit to the alpha energy spectrum using the R-matrix approach. Both the positron and neutrino energy spectra, corrected for recoil order effects, are constructed from the strength function. The positron spectrum is in good agreement with a previous direct measurement. The neutrino spectrum disagrees with previous experiments, particularly for neutrino energies above 12 MeV.Comment: 15 pages, 13 figures, 4 tables, submitted to Phys. Rev. C, typos correcte

    New broad 8Be nuclear resonances

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    Energies, total and partial widths, and reduced width amplitudes of 8Be resonances up to an excitation energy of 26 MeV are extracted from a coupled channel analysis of experimental data. The presence of an extremely broad J^pi = 2^+ ``intruder'' resonance is confirmed, while a new 1^+ and very broad 4^+ resonance are discovered. A previously known 22 MeV 2^+ resonance is likely resolved into two resonances. The experimental J^pi T = 3^(+)? resonance at 22 MeV is determined to be 3^-0, and the experimental 1^-? (at 19 MeV) and 4^-? resonances to be isospin 0.Comment: 16 pages, LaTe
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