A Five-year Spectroscopic and Photometric Campaign on the Prototypical alpha Cygni Variable and A-type Supergiant Star Deneb

Deneb is often considered the prototypical A-type supergiant, and is one of the visually most luminous stars in the Galaxy. A-type supergiants are potential extragalactic distance indicators, but the variability of these stars needs to be better characterized before this technique can be considered reliable. We analyzed 339 high resolution echelle spectra of Deneb obtained over the five-year span of 1997 through 2001 as well as 370 Stromgren photometric measurements obtained during the same time frame. Our spectroscopic analysis included dynamical spectra of the H-alpha profile, H-alpha equivalent widths, and radial velocities measured from Si II 6347, 6371. Time-series analysis reveals no obvious cyclic behavior that proceeds through multiple observing seasons, although we found a suspected 40 day period in two, non-consecutive observing seasons. Some correlations are found between photometric and radial velocity data sets, and suggest radial pulsations at two epochs. No correlation is found between the variability of the H-alpha profiles and that of the radial velocities or the photometry. Lucy (1976) found evidence that Deneb was a long period single-lined spectroscopic binary star, but our data set shows no evidence for radial velocity variations caused by a binary companion.Comment: 49 pages, 9 figures, 5 tables, accepted for publication in the Astronomical Journa

Retinoic acid induces the differentiation of B cell hybridomas from patients with common variable immunodeficiency.

Human-human B cell hybridomas constructed from B lymphocytes of common variable immunodeficiency (CVI) patients and the nonsecreting cell line WIL2/729 HF consistently secrete low levels of Ig and appear to retain a defect characteristic of the CVI patient's B cells. We assessed the differentiative capacity of retinoic acid (RA) on these hybridomas, as well as on hybridomas constructed from normal B cells and from patients with selective IgA deficiency. RA at concentrations varying between 10(-5) and 10(-9) M augmented IgM secretion 4-20-fold from four of four CVI hybridomas tested, but did not affect Ig secretion from normal or IgA-deficiency hybridomas. In support of this elevated Ig secretion, RA enhanced the de novo synthesis of biosynthetically labeled light (kappa) and heavy (mu) Ig (up to 4- and 15-fold, respectively) in the CVI hybridoma line JK32.1. The increase in IgM synthesis/secretion could not be accounted for by RA-induced alteration in the cell cycle. In inducing this increase in IgM production, RA was found to affect two aspects of Ig gene expression: (a) the steady-state levels of heavy and light chain mRNAs were enhanced, and (b) the processing of mu heavy chain transcripts to the secreted mRNA form became favored over the membrane mRNA form. We also show that expression of Leu-17 (CD38), a surface marker that is re-expressed in the late pre-plasma stage of B cell development, was increased by RA from less than 20% to greater than 90% of the total cell population, with a concomitant 4-10-fold augmentation in the mean fluorescence intensity. Changes in both Leu-17 expression and de novo Ig synthesis were prominent by 24 h, but could be observed as early as 8 h after induction. Taken together, our study demonstrates that RA affects a marked alteration in the differentiated state of the CVI hybridoma clones. This finding suggests that retinoids can enhance the functional capabilities of B cells with defects in maturation and support further studies to evaluate their clinical potential in CVI

Xenon in Mercury-Manganese Stars

Previous studies of elemental abundances in Mercury-Manganese (HgMn) stars have occasionally reported the presence of lines of the ionized rare noble gas Xe II, especially in a few of the hottest stars with Teff ~ 13000--15000 K. A new study of this element has been undertaken using observations from Lick Observatory's Hamilton Echelle Spectrograph. In this work, the spectrum synthesis program UCLSYN has been used to undertake abundance analysis assuming LTE. We find that in the Smith & Dworetsky sample of HgMn stars, Xe is vastly over-abundant in 21 of 22 HgMn stars studied, by factors of 3.1--4.8 dex. There does not appear to be a significant correlation of Xe abundance with Teff. A comparison sample of normal late B stars shows no sign of Xe II lines that could be detected, consistent with the expected weakness of lines at normal abundance. The main reason for the previous lack of widespread detection in HgMn stars is probably due to the strongest lines being at longer wavelengths than the photographic blue. The lines used in this work were 4603.03A, 4844.33A and 5292.22A.Comment: 8 pages, 4 figures. Accepted by Monthly Notices of the Royal Astronomical Society, 8 January 200

Boundary Element Solution of Electromagnetic Fields for Non-Perfect Conductors at Low Frequencies and Thin Skin Depths

A novel boundary element formulation for solving problems involving eddy currents in the thin skin depth approximation is developed. It is assumed that the time-harmonic magnetic field outside the scatterers can be described using the quasistatic approximation. A two-term asymptotic expansion with respect to a small parameter characterizing the skin depth is derived for the magnetic and electric fields outside and inside the scatterer, which can be extended to higher order terms if needed. The introduction of a special surface operator (the inverse surface gradient) allows the reduction of the problem complexity. A method to compute this operator is developed. The obtained formulation operates only with scalar quantities and requires computation of surface operators that are usual for boundary element (method of moments) solutions to the Laplace equation. The formulation can be accelerated using the fast multipole method. The method is much faster than solving the vector Maxwell equations. The obtained solutions are compared with the Mie solution for scattering from a sphere and the error of the solution is studied. Computations for much more complex shapes of different topologies, including for magnetic and electric field cages used in testing are also performed and discussed

Properties of Disks and Bulges of Spiral and Lenticular Galaxies in the Sloan Digital Sky Survey

A bulge-disk decomposition is made for 737 spiral and lenticular galaxies drawn from a SDSS galaxy sample for which morphological types are estimated. We carry out the bulge-disk decomposition using the growth curve fitting method. It is found that bulge properties, effective radius, effective surface brightness, and also absolute magnitude, change systematically with the morphological sequence; from early to late types, the size becomes somewhat larger, and surface brightness and luminosity fainter. In contrast disks are nearly universal, their properties remaining similar among disk galaxies irrespective of detailed morphologies from S0 to Sc. While these tendencies were often discussed in previous studies, the present study confirms them based on a large homogeneous magnitude-limited field galaxy sample with morphological types estimated. The systematic change of bulge-to-total luminosity ratio, $B/T$, along the morphological sequence is therefore not caused by disks but mostly by bulges. It is also shown that elliptical galaxies and bulges of spiral galaxies are unlikely to be in a single sequence. We infer the stellar mass density (in units of the critical mass density) to be $\Omega=$0.0021 for spheroids, i.e., elliptical galaxies plus bulges of spiral galaxies, and $\Omega=$0.00081 for disks.Comment: 30 pages, 9 figure

Cool White Dwarfs Identified in the Second Data Release of the UKIRT Infrared Deep Sky Survey

We have paired the Second Data Release of the Large Area Survey of the UKIRT Infrared Deep Sky Survey with the Fifth Data Release of the Sloan Digital Sky Survey to identify ten cool white dwarf candidates, from their photometry and astrometry. Of these ten, one was previously known to be a very cool white dwarf. We have obtained optical spectroscopy for seven of the candidates using the GMOS-N spectrograph on Gemini North, and have confirmed all seven as white dwarfs. Our photometry and astrometry indicates that the remaining two objects are also white dwarfs. Model analysis of the photometry and available spectroscopy shows that the seven confirmed new white dwarfs, and the two new likely white dwarfs, have effective temperatures in the range Teff = 5400-6600 K. Our analysis of the previously known white dwarf confirms that it is cool, with Teff = 3800 K. The cooling age for this dwarf is 8.7 Gyr, while that of the nine ~6000 K white dwarfs is 1.8-3.6 Gyr. We are unable to determine the masses of the white dwarfs from the existing data, and therefore we cannot constrain the total ages of the white dwarfs. The large cooling age for the coolest white dwarf in the sample, combined with its low estimated tangential velocity, suggests that it is an old member of the thin disk, or a member of the thick disk of the Galaxy, with an age 10-11 Gyr. The warmer white dwarfs appear to have velocities typical of the thick disk or even halo; these may be very old remnants of low-mass stars, or they may be relatively young thin disk objects with unusually high space motion.Comment: 37 pages (referee format), 4 tables, 7 figures, accepted to Ap

Extremely metal-poor stars from the SDSS

We give a progress report about the activities within the CIFIST Team related to the search for extremely metal-poor stars in the Sloan Digital Sky Survey's spectroscopic catalog. So far the search has provided 25 candidates with metallicities around or smaller -3. For 15 candidates high resolution spectroscopy with UVES at the VLT has confirmed their extremely metal-poor status. Work is under way to extend the search to the SDSS's photometric catalog by augmenting the SDSS photometry, and by gauging the capabilities of X-shooter when going to significantly fainter targets.Comment: 6 pages, 6 figures, Proceedings paper of the conference "A stellar journey: A symposium in celebration of Bengt Gustafsson's 65th birthday

Pathways to mental health services for young people: a systematic review

Purpose: While early access to appropriate care can minimise the sequelae of mental illnesses, little is known about how youths come to access mental healthcare. We therefore conducted a systematic review to synthesise literature on the pathways to care of youths across a range of mental health problems. Methods: Studies were identified through searches of electronic databases (MEDLINE, PsycINFO, Embase, HealthSTAR and CINAHL), supplemented by backward and forward mapping and hand searching. We included studies on the pathways to mental healthcare of individuals aged 11–30 years. Two reviewers independently screened articles and extracted data. Results: Forty-five studies from 26 countries met eligibility criteria. The majority of these studies were from settings that offered services for the early stages of psychosis, and others included inpatient and outpatient settings targeting wide-ranging mental health problems. Generally, youths’ pathways to mental healthcare were complex, involved diverse contacts, and, sometimes, undue treatment delays. Across contexts, family/carers, general practitioners and emergency rooms featured prominently in care pathways. There was little standardization in the measurement of pathways. Conclusions: Except in psychosis, youths’ pathways to mental healthcare remain understudied. Pathways to care research may need to be reconceptualised to account for the often transient and overlapping nature of youth mental health presentations, and the possibility that what constitutes optimal care may vary. Despite these complexities, additional research, using standardized methodology, can yield a greater understanding of the help-seeking behaviours of youths and those acting on their behalf; service responses to help-seeking; and the determinants of pathways. This understanding is critical to inform ongoing initatives to transform youth mental healthcare

Wandering globular clusters: the first dwarf galaxies in the universe?

In the last decade we witness an advent of new types of dwarf stellar systems in cluding ultra-compact dwarfs, ultra-faint dwarf spheroidals, and exotic globular clusters, breaking the old simple paradigm for dwarf galaxies and globular clusters. These objects become more intriguing, and understanding of these new findings be comes more challenging. Recently we discovered a new type of large scale structure in the Virgo cluster of galaxies: it is composed of globular clusters. Globular clusters in Virgo are found wandering between galaxies (intracluster globular clusters) as well as in galaxies. These intracluster globular clusters fill a significant fraction in the area of the Virgo cluster and they are dominated by blue globular clusters. These intracluster globular clusters may be closely related with the first dwarf galaxies in the universe.Comment: 6 pages, 3 figures, Conference Proceedings: "A Universe of Dwarf Galaxies", 14-18 June 2010, Lyon, Franc

The search for magnetic fields in mercury-manganese stars

We performed a highly sensitive search for magnetic fields on a large set of HgMn stars. With the aid of a new polarimeter attached to the HARPS spectrometer at the ESO 3.6m-telescope, we obtained high-quality circular polarization spectra of 41 single and double HgMn stars. Using a multi-line analysis technique on each star, we co-added information from hundreds of spectral lines resulting in significantly greater sensitivity to the presence of magnetic fields, including very weak fields. For the 47 individual objects studied, including 6 components of SB2 systems, we do not detect any magnetic fields at greater than the 3 sigma level. The lack of detection in the circular polarization profiles indicates that if strong fields are present on these stars, they must have complex surface topologies. For simple global fields, our detection limits imply upper limits to the fields present of 2-10 Gauss in the best cases. We conclude that HgMn stars lack large-scale magnetic fields, typical for spotted magnetic Ap stars, sufficient to form and sustain the chemical spots observed on HgMn stars. Our study confirms that in addition to magnetically altered atomic diffusion, there exists another differentiation mechanism operating in the atmospheres of late-B main sequence stars which can compositional inhomogeneities on their surfaces.Comment: 12 pages, 8 figures, 2 table