2,607 research outputs found

    Muslim Women’s Right to Divorce and Gender Equality Issues in Bangladesh: A Proposal for Review of Current Laws

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    In Bangladesh, sharia law goes hand in hand with the statutory laws of the land. These laws are both conjointly used to regulate and monitor the issues of divorce among Muslims of the country. Orthodox Islamic laws provide husbands with the authority of issuing divorce or talaq to their wives known as Talaq-e-Tawfiz (popularly known as tawfiz) in the kabinnama (the written document of the contract of marriage). Women’s power to exercise the tawfiz, however, depends solely on the will of their husbands. Although Muslim women are capable of repudiating their marriages by the process of khula or mubarat, these are only executable under the free consent of their husbands. Also, the statutory laws of Bangladesh address Muslim women’s right to the dissolution of marriage by the intervention of the court, only under several grounds. The traditional interpretation of sharia law and the statutory laws of the country are both unwilling to establish Muslim women’s absolute right to renounce marriage as with their male counterparts. Current research reveals that this violation of gender equality and women’s rights generates female subordination in society and gives birth to numerous socio-legal complications

    The impact of direct nucleation control on crystal size distribution in pharmaceutical crystallization processes

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    The control of crystal size distribution (CSD) in pharmaceutical crystallization is of primary importance, as downstream processes such as filtration or drying are greatly affected by the properties of the CSD. It is recognized that the variability in the final CSD is mainly caused by the significant uncertainties in the nucleation rates, and therefore, a good control of nucleation events is necessary to achieve the desired CSD. In this paper, a new direct nucleation control (DNC) approach is introduced that directly controls the apparent onset of nucleation defined as the formation of new particles with detectable size using in situ instruments. The approach uses information on nucleation and dissolution, provided by focused beam reflectance measurement (FBRM), in a feedback control strategy that adapts the process variables, so that the desired quality of product is achieved, for example large crystals with a narrow CSD. In addition, DNC provides in situ fines removal through the operating protocol, rather than having additional equipment and external recycle loops. DNC does not require concentration measurement and has the advantage of being a model-free approach, requiring no information on nucleation or growth kinetics in order to design an operating curve. The DNC approach automatically and adaptively detects the boundary of the operating zone; hence it is more robust to the presence of impurities or residual solvent than the supersaturation control approach. The approach has been applied for the crystallization of glycine and experimental results demonstrate the benefits of DNC of producing larger crystals with narrower CSD compared to classical operations

    Direct nucleation control of crystal size distribution in pharmaceutical crystallization

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    The control of crystal size distribution (CSD) in pharmaceutical crystallization is of primary importance, as downstream processes such as filtration or drying are greatly affected by the properties of the CSD. It is recognized that the variability in the final CSD is mainly caused by the significant uncertainties in the nucleation rates, and therefore, a good control of nucleation events will result in the desired CSD. In this paper, a new direct nucleation control (DNC) approach is introduced that directly controls the onset of nucleation. The approach uses information on nucleation, provided by focused beam reflectance measurement (FBRM), in a feedback control strategy that adapts the process variables, so that the desired quality of product is achieved, for example large crystals with a narrow CSD. In addition, DNC provides in situ fines removal through the operating policy, rather than having additional equipment and external recycle loops. DNC does not require concentration measurement and has the advantage of being a model-free approach, requiring no information on nucleation or growth kinetics in order to design an operating curve; the system automatically and adaptively detects the boundary of the operating curve. The approach has been applied for the crystallization of glycine and experimental results demonstrate the benefits of DNC of producing larger crystals with narrower CSD compared to classical operations

    Investigation into the prophylactic and therapeutic activity of coenzyme Q10 against COVID-19

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    Purpose: To evaluate the anti-SARS CoV-2 effect of Coenzyme Q 10, Ubiquinol-10, and idebenone, which have beneficial therapeutic applications against diverse virus types, using molecular docking approach.Methods: The potential activity of Coenzyme Q10, Ubiquinol-10, and Idebenone against viral infections was explored through the collection of data from relevant literature, and by modelling these compounds virtually, using in silico investigation methods.Results: Coenzyme Q10 and ubiquinol-10 showed significant docking performance. They interacted with numerous amino acid residues of the main protease of SARS-CoV-2 ACE2 (7C8J), Alpha thrombin (1AE8), TYRO (4TS1) protein targets sides, SARS-coronavirus Orf7a accessory protein (1XAK), TNF (1RJ8), and Cytokine/receptor (1I1R).Conclusion: The findings of our study showed promising inhibitory activities of the selected compounds against the main proteases of SARS-CoV-2. Consequently, these compounds have theoretical effects on inhibiting the viral entry, reproduction, and ultimately the prevention and/or treatment of the SARSCoV2 infection

    A Review on the Role of Nano-Communication in Future Healthcare Systems: A Big Data Analytics Perspective

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    This paper presents a first-time review of the open literature focused on the significance of big data generated within nano-sensors and nano-communication networks intended for future healthcare and biomedical applications. It is aimed towards the development of modern smart healthcare systems enabled with P4, i.e. predictive, preventive, personalized and participatory capabilities to perform diagnostics, monitoring, and treatment. The analytical capabilities that can be produced from the substantial amount of data gathered in such networks will aid in exploiting the practical intelligence and learning capabilities that could be further integrated with conventional medical and health data leading to more efficient decision making. We have also proposed a big data analytics framework for gathering intelligence, form the healthcare big data, required by futuristic smart healthcare to address relevant problems and exploit possible opportunities in future applications. Finally, the open challenges, future directions for researchers in the evolving healthcare domain, are presented

    Marketing The Non-Profit Organizations,"The Jordan Museum as a case study"

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    The aim of this paper is to analyse the existing concepts of marketing and the difficulties of applying general marketing techniques in the Jordan Museum and highlighting the strengths, weakness, threats and opportunities that are facing the museum. The paper offers marketing suggestions that may influence and assist the Jordan museum to enhance its marketing structure. The gained information for the research was obtained byusing articles, books, case studies, interviews. This method is used to gain Varity of information, points of views, and attitudes. The questions deducted in the interviews focused on whether if the Museum in question is placed on the well-known tourist trail. Another focus was upon the tools & techniques should be used in marketing. The paper also investigated if there is any marketing plan considered and whether the museums in Jordan has been discussed or even mentioned in any of the international tourism or cultural conference’s Which Jordan is invited to. The result showed that The Jordan Museum lacks any marketing innovation and having no clear marketing plan. The museum can overcome this by reconsidering its priorities enclosing new marketing techniques.  Key Words: Museums, Marketing mix, Nonprofit Organization DOI: 10.7176/JTHS/40-0

    Mechanical and thermal properties of montmorillonite-reinforced polypropylene/rice husk hybrid nanocomposites

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    © 2019 by the authors. In recent years, there has been considerable interest in the use of natural fibers as potential reinforcing fillers in polymer composites despite their hydrophilicity, which limits their widespread commercial application. The present study explored the fabrication of nanocomposites by melt mixing, using an internal mixer followed by a compression molding technique, and incorporating rice husk (RH) as a renewable natural filler, montmorillonite (MMT) nanoclay as water-resistant reinforcing nanoparticles, and polypropylene-grafted maleic anhydride (PP-g-MAH) as a compatibilizing agent. To correlate the effect ofMMTdelamination andMMT/RHdispersion in the composites, the mechanical and thermal properties of the composites were studied. XRD analysis revealed delamination of MMT platelets due to an increase in their interlayer spacing, and SEM micrographs indicated improved dispersion of the filler(s) from the use of compatibilizers. The mechanical properties were improved by the incorporation of MMT into the PP/RH system and the reinforcing effect was remarkable as a result of the use of compatibilizing agent. Prolonged water exposure of the prepared samples decreased their tensile and flexural properties. Interestingly, the maximum decrease was observed for PP/RH composites and the minimum was for MMT-reinforced and PP-g-MAH-compatibilized PP/RH composites. DSC results revealed an increase in crystallinity with the addition of filler(s), while the melting and crystallization temperatures remained unaltered. TGA revealed that MMT addition and its delamination in the composite systems improved the thermal stability of the developed nanocomposites. Overall, we conclude that MMT nanoclay is an effective water-resistant reinforcing nanoparticle that enhances the durability, mechanical properties, and thermal stability of composites

    Synthesis, optimization, DFT/TD-DFT and COX/LOX docking of new Schiff base N'-((9-ethyl-9H-carbazol-1-yl)methylene)naphthalene-2-sulfonohydrazide

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    Condensing naphthalene-2-sulfonylhydrazide with 9-ethyl-9H-carbazole-1-carbaldehyde enabled to prepare the N'-((9-ethyl-9H-carbazol-1-yl)methylene)naphthalene-2-sulfonohydrazide as new Schiff base (S.B.)  ligand with a high yield. A wide range of physicochemical measurements, such as CHN-elemental analysis, UV-Vis., NMR, FT-IR, and mass spectrometry (ESI-MS) were used to extensively investigate the structural properties of the prepared S.B. ligand. Moreover, the highest level of B3LYB/DFT also served to optimize the 3D structure of the S.B, the experimental optical UV-Vis absorption measurements was compared to the theoretical DFT/TD-DFT study under identical conditions using the same solvent. Furthermore, the anti-inflammatory possible future capability was evaluated via the LOX/COX molecular docking against the desired S.B. ligand
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