BIOLOGICAL ACTIVITY SOURCES FROM TRADITIONALLY USEDTRIBE AND HERBAL PLANTS MATERIAL

In the modern era, the consciousness about the cancer disease got enhanced and the research in the treatment of this major disease reached amilestone by spreading its influence into the terrain of the natural herbal plant kingdom to serve the humanity at a great level as 80% of the presentpopulation depends principally on tribe and herbal medicine. In chosen 9 plants of anticancer and biochemical activity such as vinblastine, vincristine,and forskoline, the artemisia connection with this, many modern drugs derive from a natural plant product which acts as chemical stimulators.Minerals and biochemical contents are determined in various traditional plants. Among those traditional plants, we have, Centella asiatica, Euclea,Euphorbia, Foeniculum vulgare, Tulbaghia violacea, from 7 different plant families in our study.Keywords: Anticancer, Antibacterial, Traditional plants, Antitoxicity, Plant extract

OPTIMIZATION OF GREEN SYNTHESIZED SILVER NANOPARTICLES FROM CARALLUMA UMBELLATA

Objective: The current study focuses on optimization and ecologically innocuous green synthesis of silver nanoparticles (AgNPs) using tribal plant Caralluma umbellata and to study its potential as an antibacterial and antifungal agent. Methods: The synthesis of AgNPs were confirmed by the colour change of the stem extract from yellow to dark brown and by UV-Visible spectroscopy. The optimum conditions for synthesis of AgNPs were analysed using Response surface methodology (RSM) based Box-Behnken design (BBD) using Design Expert software (7.0.0 trial version). The AgNPs synthesized were characterized by Scanning electron microscope (SEM), Energy dispersive X-ray (EDX), Fourier transform infrared (FTIR) and X-ray diffraction (XRD) analysis. Further, antibacterial and antifungal activity were performed using well diffusion method for both plant extract and AgNPs. Results: The UV-Visible spectrum of AgNPs revealed characteristic peak at 425.5 nm. The crystalline nature of synthesized AgNPs was confirmed by XRD with average size 26 nm. SEM confirms the spherical shape of AgNPs and by EDX the presence of elemental silver was observed. The ability of the plant to produce both reducing and capping agents were confirmed by FTIR. The optimum conditions for synthesis of AgNPs were found to be 0.55 mmol AgNO3 concentration, 45 °C temperature and 24h reaction time. Both plant sample and synthesized AgNPs exhibited good antimicrobial activity where AgNPs showed superior efficacy as an antimicrobial agent over the other. Conclusion: From the results obtained, it can be deduced that both C. umbellata stem extract and synthesized AgNPs can act as potent antimicrobial agent. But the synthesized AgNPs is more potent against bacteria and fungus

TRIBAL PLANTS AND THEIR INBORN ANTIMICROBIAL ACTIVITIES

The importance of medicinal plants in traditional health-care practices provides clues to new areas of research and in the biodiversity of conservation. Right from the beginning, the documentation of traditional knowledge, especially on the medicinal uses of plants, has provided many important drugs for the modern day. Even today, this area holds much more hidden treasure as almost 80% of the human population in developing countries depend on plant resources for health care. Keeping this in view, the present study was initiated to document the traditionally used tribal plants and their inborn antimicrobial activity which is enhanced on the synthesis of noble metal nanoparticles

Separation of m/p-Aminoacetophenone Using Hydrotropy

The aqueous solubilities of m/p-aminoacetophenone in different concentrations (0-3.0 mol/L) of hydrotropes such as diethyl nicotinamide, sodium pseudocumene sulfonate and sodium thiocyanate solutions at different system temperatures (303K to 333K) were studied. The percentage extraction (%E) of m- aminoacetophenone from m/p-aminoacetophenone mixture increases with increase in hydrotrope concentration. A Minimum Hydrotrope Concentration (MHC) in the aqueous phase was required to initiate the significance of the %E of m-aminoacetophenone. Percentage extraction (%E) is the ratio of moles of m-aminoacetophenone extracted in presence and absence of a hydrotrope. The sensitivity and feasibility of the proposed process are examined by carrying out solubilization and equilibrium precipitation experiments with the mixtures of various compositions. The effectiveness of hydrotropes was measured in terms of Setschenow constant Ks. The extraction data are also fitted in a polynomial equation as the function of hydrotrope concentration. The solubilized material can be recovered by dilution with water

The effect of hydrotropes on the solubility and mass transfer coefficient of 2-nitrobenzoic acid

A comprehensive investigation on the solubility and mass transfer coefficient enhancement of 2-nitrobenzoic acid through hydrotropy, has been undertaken. The solubility and mass transfer coefficient studies were carried out using hydrotropes such as sodium acetate, citric acid and nicotinamide under a wide range of hydrotrope concentrations (0 to 3.0 mol/L) and different system temperatures (303 to 333 K). It was found that the solubility and mass transfer coefficient of 2-nitrobenzoic acid increases with an increase in hydrotrope concentration and also with system temperature. All hydrotropes used in this work showed an enhancement in the solubility and mass transfer coefficient to different degrees. The maximum enhancement factor value has been determined for both the solubility and mass transfer coefficient. The effectiveness of hydrotropes was measured in terms of Setschnew constant Ks and reported for all the hydrotropes used in this study

The effect of hydrotropes on the solubility and mass transfer coefficient of 2-nitrobenzoic acid

A comprehensive investigation on the solubility and mass transfer coefficient enhancement of 2-nitrobenzoic acid through hydrotropy, has been undertaken. The solubility and mass transfer coefficient studies were carried out using hydrotropes such as sodium acetate, citric acid and nicotinamide under a wide range of hydrotrope concentrations (0 to 3.0 mol/L) and different system temperatures (303 to 333 K). It was found that the solubility and mass transfer coefficient of 2-nitrobenzoic acid increases with an increase in hydrotrope concentration and also with system temperature. All hydrotropes used in this work showed an enhancement in the solubility and mass transfer coefficient to different degrees. The maximum enhancement factor value has been determined for both the solubility and mass transfer coefficient. The effectiveness of hydrotropes was measured in terms of Setschnew constant Ks and reported for all the hydrotropes used in this study

A REVIEW ON INDIAN TRIBAL PLANTS AND THEIR BIOGENIC PROPERTIES

 Green synthesis of silver nanoparticles (AgNPs) is considered to be nature-friendly and risk-free to the ecosystem. India is copious in biodiversity; the traditional medicine consists of the plant as a major component. The tribal people who lived in the rural region are entirely dependent on the tribal plant for their medical emergencies. These tribal plants have attracted the modern drug industry to develop drugs which are economical with minimal side-effects. The present study focuses on the tribal plants such as Aegle marmelos, Andrographis paniculata, Acacia arabica, Ficus religiosa, Cassia auriculata, Punica granatum, and Tinospora cordifolia used by the Bhilla, Irular, Dimasa, Paliyan Sholaga, and Dantewada tribes of India for their antimicrobial activity. Since these tribal plants are well known for its medicinal properties, the AgNPs synthesized from these plants were found to have enhanced antimicrobial activity than the pure plant extract

A REVIEW ON INDIAN TRIBAL PLANTS AND THEIR BIOGENIC PROPERTIES

 Green synthesis of silver nanoparticles (AgNPs) is considered to be nature-friendly and risk-free to the ecosystem. India is copious in biodiversity; the traditional medicine consists of the plant as a major component. The tribal people who lived in the rural region are entirely dependent on the tribal plant for their medical emergencies. These tribal plants have attracted the modern drug industry to develop drugs which are economical with minimal side-effects. The present study focuses on the tribal plants such as Aegle marmelos, Andrographis paniculata, Acacia arabica, Ficus religiosa, Cassia auriculata, Punica granatum, and Tinospora cordifolia used by the Bhilla, Irular, Dimasa, Paliyan Sholaga, and Dantewada tribes of India for their antimicrobial activity. Since these tribal plants are well known for its medicinal properties, the AgNPs synthesized from these plants were found to have enhanced antimicrobial activity than the pure plant extract