Competition between structural distortion and magnetic moment formation in fullerene C20_{20}

We investigated the effect of on-site Coulomb interactions on the structural and magnetic ground state of the fullerene C$_{20}$ based on density-functional-theory calculations within the local density approximation plus on-site Coulomb corrections (LDA+$U$). The total energies of the high symmetry ($I_{h}$) and distorted ($D_{3d}$) structures of C$_{20}$ were calculated for different spin configurations. The ground state configurations were found to depend on the forms of exchange-correlation potentials and the on-site Coulomb interaction parameter $U$, reflecting the subtle nature of the competition between Jahn-Teller distortion and magnetic instability in fullerene C$_{20}$. While the non-magnetic state of the distorted $D_{3d}$ structure is robust for small $U$, a magnetic ground state of the undistorted $I_{h}$ structure emerges for $U$ larger than 4 eV when the LDA exchange-correlation potential is employed.Comment: 4 figures, 1 tabl

Numerical analysis of dielectric micro-particle motion in a fluid and electric field

We present numerical analysis of a coupled problem composed of fluidics, electromagnetic and particle dynamics. The forces acting on the dielectric micro-particle consist of a dielectrophoretic(DEP) force, drag force and gravitational force in the proposed analysis model. DEP force and drag force are calculated using the distribution of the electric field and fluid velocity field to analyze the characteristic of the micro-particle motion. The forces exerted by each field are driving terms in the Newton’s equation for particle motion. The designed particle separating device, which has the one inlet and the two outlets, is simulated to validate proposed numerical scheme. The analysis results show the trace of the micro-particles can be analyzed using the proposed numerical approach

The Effect of UVA and UVB on DNA Synthesis and Unscheduled DNA Synthesis in Mouse Skin

The effects of ultraviolet light A (UVA) and ultraviolet light B (UVB) on DNA synthesis and unscheduled DNA synthesis (UDS) were studied in mouse skin by microautoradiography. The mice were exposed to 50mJ / em" UVB by fluorescent sunlamp or 50J / ern" UVA by metal halide mercury lamp. Time course studies were performed immediately, 6 hours, 24 hours, and 48 hours after UVA and UVB exposure. There was no decreased number of heavily labeled cells (HLC) representing DNA synthesis immediately after UVA exposure and up to 48 hours postirradiation. However, immediately after and at 6 hours after UVA irradiation there was an increased number of sparsely labeled cells (SLC) representing UDS. Recovery was noticed 24 hours after irradiation and it was maintained after 48 hours postirradiation. These results clearly demonstrate that UVA induces considerable DNA damage and repair. DNA synthesis decreased immediately and at 6 hours and at 24 hours after UVB exposure. It recovered at 48 hours after UVB exposure. UDS increased immediately and at 6 hours after UVB exposure. Repair synthesis was completed at 24 hours after UVB exposure

Pion and Kaon Electromagnetic Form Factors in a SUL(3)⊗SUR(3)SU_{L}(3)\otimes SU_{R}(3) Effective Lagrangian

A SU(2) effective lagrangian is extended to a $SU_{L}(3)\otimes SU_{R}(3)$ by including the vector and axial vector meson. With this effective lagrangian, electromagnetic form factors of charged pion and kaon are calculated. The pseudoscalar meson loops are taken into account. Good agreement with experimental data is obtained for those form factors. Decay widths of $\rho\to \pi\pi$ and $\phi\to K^{+}K^{-}$ are also calculated and shown to agree with experimental data very well.Comment: 19pages, 7figure

Percutaneous Full Endoscopic Transverse Processectomy for Bertolotti’s Syndrome

The Lumbosacral transitional vertebra (LSTV) is a congenital anomaly and has two types of abnormal vertebrae. Low back pain and leg pain originated from a lumbosacral transitional vertebra (LSTV) known as Bertolotti’s syndrome (BS). We describe our institution’s experience of a L5 transverse processectomy done via a percutaneous endoscopic approach for a patient with Bertolotti’s syndrome. A 64-year-old female patient with persistent left leg radiating pain visited at the spine center. This patients underwent endoscopic L5-S1 foraminoplasty under the diagnosis of foraminal stenosis. However, despite the complete neural decompression, the patient complained of persistent left leg pain. We found that the left transverse process (TP) of L5 vertebra seemed to contact with the ala of sacrum suggesting the Bertolotti’s syndrome (BS). A pseudo-articulation lidocaine injection was given and it was effective in reducing the leg pain. Under local anesthesia, a uniportal endoscopy was introduced to the base of the L5 TP and simply cut in cranial to caudal direction using a high-speed drill in order to block the way of mechanical stress from spine. The patient’s symptoms got relieved after L5 transverse processectomy and she was discharged in a few days

Production of Transgenic Cloned Miniature Pigs with Membrane-bound Human Fas Ligand (FasL) by Somatic Cell Nuclear Transfer

Cell-mediated xenograft rejection, including NK cells and CD8+ CTL, is a major obstacle in successful pig-to-human xenotransplantation. Human CD8+ CTL and NK cells display high cytotoxicity for pig cells, mediated at least in part by the Fas/FasL pathway. To prevent cell-mediated xenocytotoxicity, a membrane-bound form of human FasL (mFasL) was generated as an inhibitor for CTL and NK cell cytotoxicity that could not be cleaved by metalloproteinase to produce putative soluble FasL. We produced two healthy transgenic pigs harboring the mFasL gene via somatic cell nuclear transfer (SCNT). In a cytotoxicity assay using transgenic clonal cell lines and transgenic pig ear cells, the rate of CD8+ CTL-mediated cytotoxicity was significantly reduced in transgenic pig's ear cells compared with that in normal minipig fetal fibroblasts. Our data indicate that grafts of transgenic pigs expressing membrane-bound human FasL control the cellular immune response to xenografts, creating a window of opportunity to facilitate xenograft survival