Letter from M. H. Myrick to John Muir, 1894 Jan 8.

[letterhead]14 Sansome StreetSan Francisco Cal.Jany 8 1894Dear Mr. Muir--Will you attend the dinner, per enclosed card, next Monday, as my guest? I think it will be worth your while. A number of bright men will be there--Bishop Nichols presiding. While it is a church club, it is entirely social and free--If you can come, please be at my room at the Palace Hotel, No 622--6th floor--at say 5 o\u27clock, & we will have an hour\u27s chat about New England.Your friendM H Myrick0176

Letter from M. H. Myrick to John Muir, 1897 Dec 14.

[letterhead]Dec. 14, 1897My dear Mr Muir-The other day some friends of ours who are readers and have traveled inquired, Do you know the man who wrote about the Stickeen dog? We said yes, we are glad to know him--he has told that story at our house. Well, said our friends, the next time he comes to you, you must let us meet him for we want to see and know a man who can write such a charming story. That, coming from such people, is praise, for they are bright people. We tell this to you, because we know your Scotch level head will not be turned.And then that article about the American Forests_ I am sure it will have effect. Mr. Runcie is going to Washington to meet [Cal?] Young_ and he will use that article with members of Congress.Last October, in a speech before the Unitarian Club here on the Hawaiian question, I used your frontispiece to Mountains of California, as a text, and I think with effect. I sent to you a copy of the pamphlet, so that you might know of my piracy. As to the dog story, I recollect I urged you to write it up, for I wanted others to know it. While,in print,it does not, of course, possess the charm of delivery in your quaint way, yet it is fine - as our friends appreciate.Said Oliver Twist, more_more! Your friendM H Myrick0237

Letter from M. H. Myrick to John Muir, [ca. 1897] ? 21.

Tuesday, 21stMy dear Mr MuirI just have yours of 19th and am glad you can come Thursday. So, Thursday be it.I sent my note of yesterday, so that Mrs. M. would know_I am happy _ God and Liberty!Ever yoursM H. MyrickResidence, 318_ 14th st, near Narrow Gauge station--Oakland--at 16th at Station, you can take Electric car, which will take you almost to my house.We can sleep you.0220

Letter from M.H. Myrick to John Muir, 1895 Jan 31.

[letterhead]Jany 31 1895Dear Mr. Muir--Your friends have thought that you knew something about mountains--but, just read the enclosed Volcanoes are [illegible]! and just see how much there is yet to learn?! Read it all, carefully, if you can.As to Lassens\u27, I know something about it. I have been there. There is no crater to Lassen--it is a sharp ridge cone. What the writer calls Bummer\u27s Hell, is not on the peak at all. It is Bumpass\u27 Hell, named after Bumpass an old mountaineer, who guided me to the place--it is at least three miles from the base of the cone, and is not a crater; but a level surface of about 60 acres, sulphur and steam springs scattered about, and often to the surrounding country.How about Shasta? Is the rim of the crater such a knife edge that explorers have had to break away the sharp crest to make a place to sleep ?And then, what about the last paragraph! In one night, a mountain thrown up, 25 miles in circumference, 2 miles high, & steam and smoke 17 miles high! and explosions heard 2000 miles!! and the tidal waves reaching dry land!! The Straits of Sunda are away southesast of Asia--so, those tidal waves must have gone around the Cape of Good Hope or Cape Horn, unless they took a short cut by India and through the Suez Canal, and over the Alps by the tunnel!!Who is this writer? Is he of enough consequence to reply to?Please return the enclosed article to me--I want it.Ever yoursM H My[illegible]I understand a tidal wave was [illegible] here at San Franciso--but there was a clear ocean wavePerhaps I am away off in laughing at him--but the thing struck me funny

Letter from M.H.Myrick to [John Muir], [ca. 1898 May].

My dear Mr MuirI must write you, that we have as much enjoyed the article on Yellowstone, in the April Atlantic - my dear friend, in this you have out done yourself.I got the magazine as soon as I was out, and read it aloud to my wife - we both want to thank you so much.We are well up in description of the Reservation, and so were better able to appreciate what you said - my wife is here, and says, I concur. She says, ask Mr Muir when he can comedown and stay overnight - and bring Mrs. Muir or if she cannot come, one of the [girls?]YoursM.H. Myrick0242

Letter from M. H. Myrick to John Muir, 1894 Jan 10.

[letterhead]14 Sansome StreetSan Francisco, Cal.Jany 10 1894John Muir, EsqDear Sir--At that banquet next Monday, a number of the leading men are to be present:Bishop Nickols, Prof. Le Conte, Dr. Stebbins, Dr. Jordan, Dr. Voursanger, the Bishop of the Methodist Church, and others--I think it is to be quite a noted affair--and hope I shall see you--YoursM H Myrick0176

Evaluating Pedagogy and Practice of Universal Design for Learning in Public Schools

How can education change to meet the demands of effectively educating an increasingly diverse student population with the skills, knowledge, and abilities they need to be productive and successful citizens in the 21st century? One possible solution is to create classrooms, teachers, and schools that embrace the progressive and inclusive practices espoused by Universal Design for Learning (UDL). In addition to being rooted in UDL pedagogy, classrooms designed to meet the challenge of 21st century education need to substantially integrate and utilize advances in technology. The vanguard of literature to date in UDL could be characterized as rhetorical advocacy. That is, UDL literature is in the early stages of introducing and promoting UDL pedagogy, but to date there is not a research base strong enough to establish UDL as a scientifically validated intervention (Edyburn, 2010). UDL might sound like a good idea, but until the research base turns the corner from advocating to assessing and measuring UDL outcomes, the promise of this approach will not be realized. This article describes a study exploring effects and outcomes of a professional development program on the perceptions and practice of UDL principles in K–12 public school inclusive classrooms, and could be one step toward bridging the gap from a good idea to a solidified best practice. Specifically, this study investigated a professional development program’s effect on teachers’ perceptions, conceptualizations, and implementation of UDL principles and practice in their classrooms

Enhancing access to alcohol use disorder pharmacotherapy and treatment in primary care settings: ADaPT-PC.

BACKGROUND: Only 7.8 % of individuals meeting diagnostic criteria for alcohol use disorder (AUD) receive treatment in a given year. Most individuals with AUDs are identified in primary care (PC) settings and referred to substance use disorders (SUD) clinics; however, only a minority of those referred attend treatment services. Safe and effective pharmacological treatments for AUD exist, but they are rarely prescribed by PC providers. The objective of this study is to refine, implement, and evaluate an intervention to integrate pharmacological AUD treatment options into PC settings. This paper provides a detailed description of the intervention design and the evaluation components. METHODS/DESIGN: Three large Veterans Health Administration (VHA) facilities are participating in the intervention. The intervention targets stakeholder groups with tailored strategies based on implementation theory and prior research identifying barriers to implementation of AUD pharmacotherapy. Local SUD providers and primary care mental health integration (PCMHI) providers are trained to serve as local implementation/clinical champions and receive external facilitation. PC providers receive access to consultation from local and national clinical champions, educational materials, and a dashboard of patients with AUD on their caseloads for case identification. Veterans with AUD diagnoses receive educational information in the mail just prior to a scheduled PC visit. Effectiveness of the intervention will be evaluated through an interrupted time series with matched controls to monitor change in facility level AUD pharmacotherapy prescribing rates. Following Stetler\u27s four-phase formative evaluation (FE) strategy, FE methods include (1) developmental FE (pre-implementation interviews with champions, PC providers, and Veterans), (2) implementation-focused FE (tracking attendance at facilitation meetings, academic detailing efforts by local champions, and patient dashboard utilization), (3) progress-focused FE (tracking rates of AUD pharmacotherapy prescribing and rates of referral to PCMHI and SUD specialty care), and (4) interpretive FE (post-implementation interviews with champions and PC providers). Analysis of FE data will be guided by the Consolidated Framework for Implementation Research (CFIR). DISCUSSION: If demonstrated to be successful, this implementation strategy will provide a replicable, feasible, and relative low-cost method for integrating AUD treatment services into PC settings, thereby increasing access to AUD treatment

Enhancing access to alcohol use disorder pharmacotherapy and treatment in primary care settings: ADaPT-PC

Background: Only 7.8% of individuals meeting diagnostic criteria for alcohol use disorder (AUD) receive treatment in a given year. Most individuals with AUDs are identified in primary care (PC) settings and referred to substance use disorders (SUD) clinics; however, only a minority of those referred attend treatment services. Safe and effective pharmacological treatments for AUD exist, but they are rarely prescribed by PC providers. The objective of this study is to refine, implement, and evaluate an intervention to integrate pharmacological AUD treatment options into PC settings. This paper provides a detailed description of the intervention design and the evaluation components. Methods/design: Three large Veterans Health Administration (VHA) facilities are participating in the intervention. The intervention targets stakeholder groups with tailored strategies based on implementation theory and prior research identifying barriers to implementation of AUD pharmacotherapy. Local SUD providers and primary care mental health integration (PCMHI) providers are trained to serve as local implementation/clinical champions and receive external facilitation. PC providers receive access to consultation from local and national clinical champions, educational materials, and a dashboard of patients with AUD on their caseloads for case identification. Veterans with AUD diagnoses receive educational information in the mail just prior to a scheduled PC visit. Effectiveness of the intervention will be evaluated through an interrupted time series with matched controls to monitor change in facility level AUD pharmacotherapy prescribing rates. Following Stetler\u27s four-phase formative evaluation (FE) strategy, FE methods include (1) developmental FE (pre-implementation interviews with champions, PC providers, and Veterans), (2) implementation-focused FE (tracking attendance at facilitation meetings, academic detailing efforts by local champions, and patient dashboard utilization), (3) progress-focused FE (tracking rates of AUD pharmacotherapy prescribing and rates of referral to PCMHI and SUD specialty care), and (4) interpretive FE (post- implementation interviews with champions and PC providers). Analysis of FE data will be guided by the Consolidated Framework for Implementation Research (CFIR). Discussion: If demonstrated to be successful, this implementation strategy will provide a replicable, feasible, and relative low-cost method for integrating AUD treatment services into PC settings, thereby increasing access to AUD treatment

Extensive dynamics of Plasmodium falciparum densities, stages and genotyping profiles

<p>Abstract</p> <p>Background</p> <p>Individuals living in areas of high malaria transmission often have different <it>Plasmodium falciparum </it>clones detected in the peripheral blood over time. The aim of this study was to assess the dynamics of asymptomatic <it>P. falciparum </it>infections in a few hours intervals.</p> <p>Methods</p> <p>Capillary blood samples were collected 6-hourly during five days from asymptomatic children in a highly endemic area in Tanzania. Parasite densities and maturation stages were investigated by light microscopy. Types and number of clones were analysed by PCR based genotyping of the polymorphic merozoite surface proteins 1 and 2 genes. Results: Parasite densities and maturation stages fluctuated 48-hourly with a gradual shift into more mature forms. Various genotyping patterns were observed in repeated samples over five days with only few samples with identical profiles. Up to six alleles differed in samples collected six hours apart in the same individual.</p> <p>Conclusion</p> <p>This detailed assessment highlights the extensive within-host dynamics of <it>P. falciparum </it>populations and the limitations of single blood samples to determine parasite densities, stages and genotyping profiles in a malaria infected individual.</p