BLAZE: Bettering the lives of animals in zoo environments

Gemstone Team BLAZECaptivity can induce high levels of stress in zoo animals, leading to health and behavioral problems that hamper conservation efforts, reduce the effectiveness of education, and negatively affect animal welfare. Zoos employ environmental enrichment to mitigate stress, but the effectiveness of various types of enrichment is poorly understood. We surveyed enrichment practices at 39 zoos nationwide and then used noninvasive fecal hormone analyses to monitor stress in three species of felids under different enrichment programs at two zoos. Baseline analyses at the National Zoological Park showed individual differences in stress hormone levels but no seasonal effects. Contrary to expectations, a novel enrichment program at Plumpton Park Zoo produced higher cortisol levels than a reduced enrichment program. Results suggest that novel objects that elicit active engagement may cause transient increases in stress hormones. Further long-term study is needed to elucidate whether this has a positive or negative effect on well-being

What\u27s in a Name? Accurately Diagnosing Metopic Craniosynostosis Using a Computational Approach.

BACKGROUND: The metopic suture is unlike other cranial sutures in that it normally closes in infancy. Consequently, the diagnosis of metopic synostosis depends primarily on a subjective assessment of cranial shape. The purpose of this study was to create a simple, reproducible radiographic method to quantify forehead shape and distinguish trigonocephaly from normal cranial shape variation. METHODS: Computed tomography scans were acquired for 92 control patients (mean age, 4.2 ± 3.3 months) and 18 patients (mean age, 6.2 ± 3.3 months) with a diagnosis of metopic synostosis. A statistical model of the normal cranial shape was constructed, and deformation fields were calculated for patients with metopic synostosis. Optimal and divergence (simplified) interfrontal angles (IFA) were defined based on the three points of maximum average deformation on the frontal bones and metopic suture, respectively. Statistical analysis was performed to assess the accuracy and reliability of the diagnostic procedure. RESULTS: The optimal interfrontal angle was found to be significantly different between the synostosis (116.5 ± 5.8 degrees; minimum, 106.8 degrees; maximum, 126.6 degrees) and control (136.7 ± 6.2 degrees; minimum, 123.8 degrees; maximum, 169.3 degrees) groups (p \u3c 0.001). Divergence interfrontal angles were also significantly different between groups. Accuracy, in terms of available clinical diagnosis, for the optimal and divergent angles, was 0.981 and 0.954, respectively. CONCLUSIONS: Cranial shape analysis provides an objective and extremely accurate measure by which to diagnose abnormal interfrontal narrowing, the hallmark of metopic synostosis. The simple planar angle measurement proposed is reproducible and accurate, and can eliminate diagnostic subjectivity in this disorder. CLINICAL QUESTION/LEVEL OF EVIDENCE: Diagnostic, IV