Neurovascular compression of the left rostral ventrolateral medulla: clinic findings and surgical result

Neurovascular compression syndromes of the rostral ventrolateral (RVL) medulla occur rarely. These syndromes reveal different clinical symptoms such as trigeminal neuralgia, hemifacial spasm, and glossopharyngeal neuralgia. We presented a case of 49-year-old male patient with left-sided trigeminal neuralgia, hemifacial spasm, and arterial hypertension. Magnetic resonance imaging (MRI) and angiography (MRA) showed a large tortuous basilar artery. Microvascular decompression (MVD) was successfully performed to decompress the nerves and the RVL medulla oblongata. Postoperatively, the patient had no trigeminal neuralgia and hemifacial spasm and his arterial blood pressure measurements were in normal limits without medication. An elongated basilar artery with compression of the brainstem is a much rarer condition. Our case demonstrated that if the patients have cranial neuropathies with arterial hypertension such as trigeminal neuralgia, hemifacial spasm, glossopharyngeal neuralgia, the patients should be carefully examined and profoundly evaluated with thin slice MRI especially posterior fossa. We emphasize that MVD is the gold standard in neurovascular compression syndromes

What is the Most Appropriate Animal Model for Experimental Diabetic Neuropathy Studies ?

[Arch Clin Exp Surg 2012; 1(3.000): 199-200

Densitometric analysis of dopaminergic neurons in substantia nigra and striatum in genetic absence epilepsy rat strain

İstanbul Bilim Üniversitesi, Tıp Fakültesi.WAG/Rij ırkı sıçanlar tipik absans epilepsinin iyi tanımlanmış modellerinden biridir. Son yıllarda yapılan çalışmalarda absans epilepside dopaminerjik sistemin bozukluğunun rol oynadığı ileri sürülmektedir. Orta beyin yapılarından biri olan substansiya nigra (SN) motor fonksiyonların düzenlenmesinde ve nöbet kontrolünde önemli bir rol oynamaktadır. Substansiya nigra ve striatumun fonksiyonları büyük ölçüde dopamin tarafından modüle edilir. Bu çalışmada WAG/Rij ve Wistar sıçanlar arasında SN ve striatumun dopaminerjik aktivitesi tirozin hidroksilaz (TH) immünhistokimya yöntemi ile karşılaştırılmıştır

Isolated unilateral hypoglossal nerve paralysis: A case report

Isolated unilateral hypoglossal nerve paralysis is a rare condition. The etiologic factors that may cause this are cancer metastases, infection, endocrine, neurological, autoimmune and vascular reasons. A 56-year-old male patient complained of swelling, speech impairment and biting the left side of the tongue for 2 years. [Med-Science 2017; 6(3.000): 613-

Effects of Medication Adherence in Epilepsy Patients On Quality of Life

Objectives:This study aimed to observe epileptic patients on drug compliance and its effects on their quality of life to reveal the effects of socio-demographic and disease-related characteristics on drug compliance and quality of life.Methods:This study was performed with self-filling and face-to-face interview method with 84 epileptic patients, who were selected by a random sampling method from those who applied to GATA Haydarpaşa Training Hospital, Neurology Polyclinic, between January and June 2014. When data related to patients were collected, an introductive patient interview form, which contains information about the disease, the Morisky Medication Adherence Scale, indicating drug compliance, and the short form-36 scale, which measures quality of life, were used.Results:Patients with a high drug compliance were found to have significantly higher scores on emotional role (p<0.043), viability (p<0.000), mental health (p<0.002), and general health (p<0.000).Conclusion:We recommend making efforts to eliminate the negativity, if there is any, and to increase the quality of life by evaluating the factors that may influence drug compliance in patients on an individual basis considering low drug compliance therefore low quality of life groups

Presentation of moyamoya disease with occipital hemorrhage: a case report

Moyamoya disease is a cerebrovascular disease which is characterized with stenosis and occlusions at the distal part of internal carotid artery and at the proximal part of anterior and middle cerebral arteries. It rarely causes temporary or recurrent hemiparesis due to intracranial hemorrhage while symptoms like headache, convulsion, nystagmus, aphasia and ataxia may also occur. In this paper, we present a case of Moyamoya disease which was diagnosed with a 23 year old female patient who was admitted to our emergency department with headache, nausea and vomiting complaints and whose radiological findings showed occipital lobe hemorrhage