Linear regression analysis.

<p>The main effect of VO₂max (L·min⁻¹) on BMI was significant (p<0.001). The main effects of <i>FTO</i> genotype and <i>FTO</i> genotype-VO₂max (L·min⁻¹) interaction were not significant (p = 0.964 and p = 0.937, respectively).</p

Linear regression analysis.

<p>The main effect of VO₂max (mL·kg⁻¹·min⁻¹) on waist circumference was significant (p<0.001). The main effects of <i>FTO</i> genotype and <i>FTO</i> genotype-VO₂max (mL·kg⁻¹·min⁻¹) interaction were not significant (p = 0.040 and p = 0.093, respectively).</p

Showing the results of ANCOVA–analysis according to <i>FTO</i> genotype.

<p>Earlier physical activity, smoking and age were set as covariates. Bonferroni correction was accounted for multiple post-hoc comparisons.</p><p>BMI: p = 0.007 for main effect, *p = 0.005 between the genotype groups CC and AA.</p><p>Waist circumference: p = 0.012 for main effect, #p = 0.012 between the genotype groups CC and AA.</p><p>p>0.0125 for main effect between genotype groups for rest of the variables.</p

Showing results of the logistic regression analysis.

<p>OR and 95% C.I. for the genotype AA (vs. genotype CA and CC) of the <i>FTO</i> rs8050136 according to overweight and abdominal obesity.</p

Linear regression analysis.

<p>The main effect of VO₂max (mL·kg⁻¹·min⁻¹) on BMI was significant (p<0.001). The main effects of <i>FTO</i> genotype and <i>FTO</i> genotype-VO₂max (mL·kg⁻¹·min⁻¹) interaction were not significant (p = 0.029 and p = 0.081, respectively).</p

The experimental protocol.

<p>The experimental protocol.</p

Energy intake, macronutrient composition of the consumed food and water balance during the 8-day training course among the control and Ebar groups.

<p>Values are mean ± SD.</p>a<p>Estimated from food recods.</p>b<p>Energy availability  =  energy intake/basal metabolic rate estimated by the equation of Schofield et al. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0047771#pone.0047771-Schofield1" target="_blank">[32]</a>.</p>c<p>Estimated from fluid intake records.</p>d<p>Total water intake  =  fluid intake + water content of food + metabolic water.</p

Physical characteristics of the control and Ebar groups before the training course.

<p>Values are mean ± SD.</p>aa<p>Estimated from 12-minute running test: VO₂max (ml·kg⁻¹·min⁻¹)  =  running distance (m) - 504.9/44.7 <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0047771#pone.0047771-Cooper1" target="_blank">[57]</a>.</p

Pearson correlation coefficient between physical activity, energy availability and water balance and questionnaire data during the 8-day training course.

***<p>P<0.001,</p>**<p>P<0.01,</p>*<p>P<0.05.</p

Changes (%) in physical performance in the control and Ebar groups during the study.

<p>Differences in change compared to the controls ## P<0.01. Differences in absolute change within the group compared to: -6 PRE ∧∧∧ P<0.001, ∧ P<0.05; PRE ***P<0.001, **P<0.01; MID $ P<0.05.</p