6 research outputs found

    'Red flags of corruption'in world bank projects : an analysis of infrastructure contracts

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    "Red flags"are indicators of potential issues regarding governance failure, collusion or corruption in projects. While some specific red flags can be powerful indicators of issues to be addressed, the hypothesis of this paper is that many proposed red flags are potentially too ubiquitous and randomly distributed to be useful as indicators of significant governance failure. The paper examines project documentation from a small sample of World Bank water and sanitation projects in an attempt to collect data on the presence or absence of 13 commonly accepted red flags. This paper finds that: (i) almost every contract reviewed raised at least one of 13 red flags analyzed; (ii) potentially tainted contracts did not exhibit notably more red flags than control contracts; and (iii) the occurrence of multiple red flags in the same contract was rare enough to suggest that joint occurrence was largely by chance, not as a result of a strongly causal inter-relationship between flags. The ubiquity and apparent randomness of these red flags suggests that their roll-out as a monitoring tool requires additional thought as to interpretation, context and use. The paper examines an alternate tool for uncovering potential problem projects -- supplier concentration. Across a very small sample, there does appear to be a relationship between such concentration and potential problem projects.Post Conflict Reconstruction,Debt Markets,Government Procurement,Investment and Investment Climate,Literature&Folklore

    Intensity of Russian Companies’ Mergers & Acquisitions (M&A) Processes, 2001-2004: Econometric Estimation

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    The article uses econometric tools to analyze and identify main characteristics of mergers & acquisitions of Russian companies at the time of economic growth. We employ the Poisson regression to model M&A behavior, and its relation with macroeconomic indicators, while controlling for a linear trend and seasonality. It is one of the first attempts to estimate a similar model for Russian M&A.mergers and acquisitions; Poisson regression

    УсилСниС экономичСских ΠΏΠΎΠ·ΠΈΡ†ΠΈΠΉ российской элСктроники: ΠΌΠ΅Ρ…Π°Π½ΠΈΠ·ΠΌΡ‹ ΠΈ возмоТности

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    The research analyzes the changes in economic relations between the state and economic entities in the electronics market. It is for the first time when we discuss the author’s classification, which identifies four types of models of interaction between the state and Russian electronics companies depending on changes in the business cycle and instability of the economy: an inert or passive observer, a crisis model, dynamic and rational participation, and a model of active and multi-agency interactions. Specific characteristics of the proposed models are identified, and the features of interaction between government structures and companies are systematized. The research shows an increasing role of the state in supporting and financing new directions of the development of integrated structures in electronics, despite the processes of globalization and liberalization of the national economy. The novelty of the research is in the development of a comprehensive view on the institutional structure of state support for electronics. An active process of formation of complex-structured economic entities at the industry, inter-industry and interregional levels on the basis of state strategies for the development of electronics is analyzed. The specificity of modern behaviour of Russian electronics companies in the digital economy and the coronavirus pandemic is revealed on the basis of generalization of stylized facts of the specific companies’ activitiesИсслСдованиС посвящСно Π°Π½Π°Π»ΠΈΠ·Ρƒ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ хозяйствСнных ΠΎΡ‚Π½ΠΎΡˆΠ΅Π½ΠΈΠΉ ΠΌΠ΅ΠΆΠ΄Ρƒ государством ΠΈ ΡΡƒΠ±ΡŠΠ΅ΠΊΡ‚Π°ΠΌΠΈ экономики Π½Π° Ρ€Ρ‹Π½ΠΊΠ΅ элСктроники. Π’ΠΏΠ΅Ρ€Π²Ρ‹Π΅ обсуТдаСтся авторская классификация, Π²Ρ‹Π΄Π΅Π»ΡΡŽΡ‰Π°Ρ Ρ‡Π΅Ρ‚Ρ‹Ρ€Π΅ Ρ‚ΠΈΠΏΠ° ΠΌΠΎΠ΄Π΅Π»Π΅ΠΉ взаимодСйствия государства ΠΈ российских ΠΊΠΎΠΌΠΏΠ°Π½ΠΈΠΉ элСктроники Π² зависимости ΠΎΡ‚ измСнСния Π΄Π΅Π»ΠΎΠ²ΠΎΠ³ΠΎ Ρ†ΠΈΠΊΠ»Π° ΠΈ Π½Π΅ΡΡ‚Π°Π±ΠΈΠ»ΡŒΠ½ΠΎΡΡ‚ΠΈ экономики: ΠΈΠ½Π΅Ρ€Ρ‚Π½ΠΎΠ³ΠΎ ΠΈΠ»ΠΈ пассивного Π½Π°Π±Π»ΡŽΠ΄Π°Ρ‚Π΅Π»Ρ, кризисная, Π΄ΠΈΠ½Π°ΠΌΠΈΡ‡Π½ΠΎΠ³ΠΎ ΠΈ Ρ€Π°Ρ†ΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ участия, модСль Π°ΠΊΡ‚ΠΈΠ²Π½Ρ‹Ρ… ΠΈ ΠΌΡƒΠ»ΡŒΡ‚ΠΈΠ°Π³Π΅Π½Ρ‚ΡΠΊΠΈΡ… взаимодСйствий. ВыявлСны спСцифичСскиС характСристики ΠΏΡ€Π΅Π΄Π»ΠΎΠΆΠ΅Π½Π½Ρ‹Ρ… ΠΌΠΎΠ΄Π΅Π»Π΅ΠΉ, систСматизированы особСнности взаимодСйствия властных структур ΠΈ ΠΊΠΎΠΌΠΏΠ°Π½ΠΈΠΉ. Показано возрастаниС Ρ€ΠΎΠ»ΠΈ государства Π² ΠΏΠΎΠ΄Π΄Π΅Ρ€ΠΆΠΊΠ΅ ΠΈ финансировании Π½ΠΎΠ²Ρ‹Ρ… Π½Π°ΠΏΡ€Π°Π²Π»Π΅Π½ΠΈΠΉ развития ΠΈΠ½Ρ‚Π΅Π³Ρ€ΠΈΡ€ΠΎΠ²Π°Π½Π½Ρ‹Ρ… структур Π² элСктроникС, нСсмотря Π½Π° процСссы Π³Π»ΠΎΠ±Π°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ ΠΈ Π»ΠΈΠ±Π΅Ρ€Π°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ Π½Π°Ρ†ΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠΉ экономики. Новизна исслСдования Π·Π°ΠΊΠ»ΡŽΡ‡Π°Π΅Ρ‚ΡΡ Π² Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠ΅ комплСксного прСдставлСния ΠΎΠ± ΠΈΠ½ΡΡ‚ΠΈΡ‚ΡƒΡ†ΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠΉ структурС государствСнной ΠΏΠΎΠ΄Π΄Π΅Ρ€ΠΆΠΊΠΈ элСктроники. АнализируСтся Π°ΠΊΡ‚ΠΈΠ²Π½Ρ‹ΠΉ процСсс формирования слоТноструктурированных Ρ…ΠΎΠ·ΡΠΉΡΡ‚Π²ΡƒΡŽΡ‰ΠΈΡ… ΡΡƒΠ±ΡŠΠ΅ΠΊΡ‚ΠΎΠ² отраслСвого, мСТотраслСвого ΠΈ ΠΌΠ΅ΠΆΡ€Π΅Π³ΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ ΡƒΡ€ΠΎΠ²Π½Π΅ΠΉ Π½Π° Π±Π°Π·Π΅ государствСнных стратСгий развития элСктроники. ΠžΠ±ΡΡƒΠΆΠ΄Π°Π΅Ρ‚ΡΡ соврСмСнноС ΠΏΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠ΅ российских ΠΊΠΎΠΌΠΏΠ°Π½ΠΈΠΉ элСктроники Π² условиях Ρ†ΠΈΡ„Ρ€ΠΎΠ²ΠΎΠΉ экономики ΠΈ ΠΏΠ°Π½Π΄Π΅ΠΌΠΈΠΈ коронавируса Π½Π° основС обобщСния стилизованных Ρ„Π°ΠΊΡ‚ΠΎΠ² Π΄Π΅ΡΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΠΈ ΠΊΠΎΠ½ΠΊΡ€Π΅Ρ‚Π½Ρ‹Ρ… ΠΊΠΎΠΌΠΏΠ°Π½ΠΈ

    Π€ΠΎΡ€ΠΌΠΈΡ€ΠΎΠ²Π°Π½ΠΈΠ΅ ΠΏΡ€ΠΎΠ°ΠΊΡ‚ΠΈΠ²Π½Ρ‹Ρ… стратСгий китайских Ρ„ΠΎΠ½Π΄ΠΎΠ² прямых частных инвСстиций Π½Π° российском Ρ€Ρ‹Π½ΠΊΠ΅ ΠΊΠΎΡ€ΠΏΠΎΡ€Π°Ρ‚ΠΈΠ²Π½ΠΎΠ³ΠΎ контроля

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    The article discusses the boundaries and contours of the possible institutional behavior of private equity funds (PEFs) in the Russian Federation in modern conditions. It analyzes the transformation of PEF sectoral interests in the Russian assets of non-public companies in the period of economic instability. Besides, it gives a relevant assessment of changes in the regional aspects of interaction between PEFs and recipient companies from Russia against the background of sanctions and import substitution, as well as private equity cycle. The article presents the modern metrics of Chinese PEFs and a multi-level monitoring of existing Chinese PEF projects in the Russian economy. It also analyzes the effects of multi-agent relations of PEFs and target companies in Russia against the background of a gradual recovery of the country’s economic growth. The article discusses the current and preferred format for the participation of investors in the PE market in the context of the adaptation of the Russian economy to the sanctions regime. It identifies the factors affecting the prospects and dynamics of the development of Chinese PEFs with an investment mandate for Russia and discusses the mechanisms of institutional support for expanding the presence of Chinese PEs in the Russian market for corporate controlΠ’ ΡΡ‚Π°Ρ‚ΡŒΠ΅ рассмотрСны Π³Ρ€Π°Π½ΠΈΡ†Ρ‹ ΠΈ ΠΊΠΎΠ½Ρ‚ΡƒΡ€Ρ‹ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΠ³ΠΎ ΠΈΠ½ΡΡ‚ΠΈΡ‚ΡƒΡ†ΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ повСдСния Ρ„ΠΎΠ½Π΄ΠΎΠ² прямых частных инвСстиций (PEF) Π² Π Π€ Π² соврСмСнных условиях. АнализируСтся трансформация отраслСвых интСрСсов со стороны PEF ΠΊ российским Π°ΠΊΡ‚ΠΈΠ²Π°ΠΌ Π½Π΅ΠΏΡƒΠ±Π»ΠΈΡ‡Π½Ρ‹Ρ… ΠΊΠΎΠΌΠΏΠ°Π½ΠΈΠΉ Π² ΠΏΠ΅Ρ€ΠΈΠΎΠ΄ экономичСской Π½Π΅ΡΡ‚Π°Π±ΠΈΠ»ΡŒΠ½ΠΎΡΡ‚ΠΈ. Π”Π°Π½Π° рСлСвантная ΠΎΡ†Π΅Π½ΠΊΠ° измСнСнию Ρ€Π΅Π³ΠΈΠΎΠ½Π°Π»ΡŒΠ½Ρ‹Ρ… аспСктов взаимодСйствия PEF ΠΈ ΠΊΠΎΠΌΠΏΠ°Π½ΠΈΠΉ-Ρ€Π΅Ρ†ΠΈΠΏΠΈΠ΅Π½Ρ‚ΠΎΠ² ΠΈΠ· России Π½Π° Ρ„ΠΎΠ½Π΅ санкций ΠΈ импортозамСщСния, цикличности Ρ€Ρ‹Π½ΠΊΠ° (PE). ΠŸΡ€Π΅Π΄ΡΡ‚Π°Π²Π»Π΅Π½Ρ‹ соврСмСнныС ΠΌΠ΅Ρ‚Ρ€ΠΈΠΊΠΈ китайских PEF, осущСствлСн ΠΌΠ½ΠΎΠ³ΠΎΡƒΡ€ΠΎΠ²Π½Π΅Π²Ρ‹ΠΉ ΠΌΠΎΠ½ΠΈΡ‚ΠΎΡ€ΠΈΠ½Π³ Π΄Π΅ΠΉΡΡ‚Π²ΡƒΡŽΡ‰ΠΈΡ… ΠΏΡ€ΠΎΠ΅ΠΊΡ‚ΠΎΠ² китайских PΠ•F Π² экономикС России. ΠŸΡ€ΠΎΠ²Π΅Π΄Π΅Π½ Π°Π½Π°Π»ΠΈΠ· послСдствий ΠΌΡƒΠ»ΡŒΡ‚ΠΈΠ°Π³Π΅Π½Ρ‚ΡΠΊΠΈΡ… ΠΎΡ‚Π½ΠΎΡˆΠ΅Π½ΠΈΠΉ PEF ΠΈ Ρ†Π΅Π»Π΅Π²Ρ‹Ρ… ΠΊΠΎΠΌΠΏΠ°Π½ΠΈΠΉ Π² России Π½Π° Ρ„ΠΎΠ½Π΅ постСпСнного восстановлСния экономичСского роста страны. ΠžΠ±ΡΡƒΠΆΠ΄Π°Π΅Ρ‚ΡΡ слоТившийся ΠΈ ΠΏΡ€Π΅Π΄ΠΏΠΎΡ‡ΠΈΡ‚Π°Π΅ΠΌΡ‹ΠΉ Ρ„ΠΎΡ€ΠΌΠ°Ρ‚ участия инвСсторов Π½Π° Ρ€Ρ‹Π½ΠΊΠ΅ PE Π² условиях Π°Π΄Π°ΠΏΡ‚Π°Ρ†ΠΈΠΈ российской экономики ΠΊ санкционному Ρ€Π΅ΠΆΠΈΠΌΡƒ. ВыявлСны Ρ„Π°ΠΊΡ‚ΠΎΡ€Ρ‹, Π²Π»ΠΈΡΡŽΡ‰ΠΈΠ΅ Π½Π° пСрспСктивы ΠΈ Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΡƒ развития китайских PEF с инвСстиционным ΠΌΠ°Π½Π΄Π°Ρ‚ΠΎΠΌ Π½Π° Россию. ΠžΠ±ΡΡƒΠΆΠ΄Π°ΡŽΡ‚ΡΡ ΠΌΠ΅Ρ…Π°Π½ΠΈΠ·ΠΌΡ‹ ΠΈΠ½ΡΡ‚ΠΈΡ‚ΡƒΡ†ΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠΉ ΠΏΠΎΠ΄Π΄Π΅Ρ€ΠΆΠΊΠΈ Ρ€Π°ΡΡˆΠΈΡ€Π΅Π½ΠΈΡ присутствия китайских PE Π½Π° российском Ρ€Ρ‹Π½ΠΊΠ΅ ΠΊΠΎΡ€ΠΏΠΎΡ€Π°Ρ‚ΠΈΠ²Π½ΠΎΠ³ΠΎ ΠΊΠΎΠ½Ρ‚Ρ€ΠΎΠ»

    Ultrastructural Abnormalities in Induced Pluripotent Stem Cell-Derived Neural Stem Cells and Neurons of Two Cohen Syndrome Patients

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    Cohen syndrome is an autosomal recessive disorder caused by VPS13B (COH1) gene mutations. This syndrome is significantly underdiagnosed and is characterized by intellectual disability, microcephaly, autistic symptoms, hypotension, myopia, retinal dystrophy, neutropenia, and obesity. VPS13B regulates intracellular membrane transport and supports the Golgi apparatus structure, which is critical for neuron formation. We generated induced pluripotent stem cells from two patients with pronounced manifestations of Cohen syndrome and differentiated them into neural stem cells and neurons. Using transmission electron microscopy, we documented multiple new ultrastructural changes associated with Cohen syndrome in the neuronal cells. We discovered considerable disturbances in the structure of some organelles: Golgi apparatus fragmentation and swelling, endoplasmic reticulum structural reorganization, mitochondrial defects, and the accumulation of large autophagosomes with undigested contents. These abnormalities underline the ultrastructural similarity of Cohen syndrome to many neurodegenerative diseases. The cell models that we developed based on patient-specific induced pluripotent stem cells can serve to uncover not only neurodegenerative processes, but the causes of intellectual disability in general
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