34,163 research outputs found

    Understanding 401(k) plans

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    Questions about the future of the Social Security system continue to surface. As a result, interest in employer-sponsored retirement plans and other retirement investment options increases. But the restrictions and rules associated with various defined benefit plans such as 401(k), 403 (b), and 457 plans can be confusing, and these plans have risks of their own. The authors explore these plans and explain the need to view retirement savings as only one part of a portfolio.

    Galaxies into the Dark Ages

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    We consider the capabilities of current and future large facilities operating at 2\,mm to 3\,mm wavelength to detect and image the [CII] 158\,μ\mum line from galaxies into the cosmic "dark ages" (z10z \sim 10 to 20). The [CII] line may prove to be a powerful tool in determining spectroscopic redshifts, and galaxy dynamics, for the first galaxies. We emphasize that the nature, and even existence, of such extreme redshift galaxies, remains at the frontier of open questions in galaxy formation. In 40\,hr, ALMA has the sensitivity to detect the integrated [CII] line emission from a moderate metallicity, active star-forming galaxy [ZA=0.2ZZ_A = 0.2\,Z_{\odot}; star formation rate (SFR) = 5\,MM_\odot\,yr1^{-1}], at z=10z = 10 at a significance of 6σ\sigma. The next-generation Very Large Array (ngVLA) will detect the integrated [CII] line emission from a Milky-Way like star formation rate galaxy (ZA=0.2ZZ_{A} = 0.2\,Z_{\odot}, SFR = 1\,MM_\odot\,yr1^{-1}), at z=15z = 15 at a significance of 6σ\sigma. Imaging simulations show that the ngVLA can determine rotation dynamics for active star-forming galaxies at z15z \sim 15, if they exist. Based on our very limited knowledge of the extreme redshift Universe, we calculate the count rate in blind, volumetric surveys for [CII] emission at z10z \sim 10 to 20. The detection rates in blind surveys will be slow (of order unity per 40\,hr pointing). However, the observations are well suited to commensal searches. We compare [CII] with the [OIII] 88μ\mum line, and other ancillary information in high zz galaxies that would aid these studies.Comment: 11pages, 8 figures, Accepted for the Astrophysical Journa

    Enhanced dust heating in the bulges of early-type spiral galaxies

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    Stellar density and bar strength should affect the temperatures of the cool (T ~ 20–30 K) dust component in the inner regions of galaxies, which implies that the ratio of temperatures in the circumnuclear regions to the disk should depend on Hubble type. We investigate the differences between cool dust temperatures in the central 3 kpc and disk of 13 nearby galaxies by fitting models to measurements between 70 and 500 μm. We attempt to quantify temperature trends in nearby disk galaxies, with archival data from Spitzer/MIPS and new observations with Herschel/SPIRE, which were acquired during the first phases of the Herschel observations for the KINGFISH (Key Insights on Nearby Galaxies: a Far-Infrared Survey with Herschel) sample. We fit single-temperature modified blackbodies to far-infrared and submillimeter measurements of the central and disk regions of galaxies to determine the temperature of the component(s) emitting at those wavelengths. We present the ratio of central-region-to-disk-temperatures of the cool dust component of 13 nearby galaxies as a function of morphological type. We find a significant temperature gradient in the cool dust component in all galaxies, with a mean center-to-disk temperature ratio of 1.15 ± 0.03. The cool dust temperatures in the central ~3 kpc of nearby galaxies are 23 (±3)% hotter for morphological types earlier than Sc, and only 9 (±3)% hotter for later types. The temperature ratio is also correlated with bar strength, with only strongly barred galaxies having a ratio over 1.2. The strong radiation field in the high stellar density of a galactic bulge tends to heat the cool dust component to higher temperatures, at least in early-type spirals with relatively large bulges, especially when paired with a strong bar

    A two-compartment mechanochemical model of the roles of\ud transforming growth factor β and tissue tension in dermal wound healing

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    The repair of dermal tissue is a complex process of interconnected phenomena, where cellular, chemical and mechanical aspects all play a role, both in an autocrine and in a paracrine fashion. Recent experimental results have shown that transforming growth factor−β (TGFβ) and tissue mechanics play roles in regulating cell proliferation, differentiation and the production of extracellular materials. We have developed a 1D mathematical model that considers the interaction between the cellular, chemical and mechanical phenomena, allowing the combination of TGFβ and tissue stress to inform the activation of fibroblasts to myofibroblasts. Additionally, our model incorporates the observed feature of residual stress by considering the changing zero-stress state in the formulation for effective strain. Using this model, we predict that the continued presence of TGFβ in dermal wounds will produce contractures due to the persistence of myofibroblasts; in contrast, early elimination of TGFβ significantly reduces the myofibroblast numbers resulting in an increase in wound size. Similar results were obtained by varying the rate at which fibroblasts differentiate to myofibroblasts and by changing the myofibroblast apoptotic rate. Taken together, the implication is that elevated levels of myofibroblasts is the key factor behind wounds healing with excessive contraction, suggesting that clinical strategies which aim to reduce the myofibroblast density may reduce the appearance of contractures

    A fibrocontractive mechanochemical model of dermal wound\ud closure incorporating realistic growth factor kinetics

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    Fibroblasts and their activated phenotype, myofibroblasts, are the primary cell types involved in the contraction associated with dermal wound healing. Recent experimental evidence indicates that the transformation from fibroblasts to myofibroblasts involves two distinct processes: the cells are stimulated to change phenotype by the combined actions of transforming growth factor β (TGFβ) and mechanical tension. This observation indicates a need for a detailed exploration of the effect of the strong interactions between the mechanical changes and growth factors in dermal wound healing. We review the experimental findings in detail and develop a model of dermal wound healing that incorporates these phenomena. Our model includes the interactions between TGFβ and collagenase, providing a more biologically realistic form for the growth factor kinetics than those included in previous mechanochemical descriptions. A comparison is made between the model predictions and experimental data on human dermal wound healing and all the essential features are well matched

    Intrinsic dissipation in high-frequency micromechanical resonators

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    We report measurements of intrinsic dissipation in micron-sized suspended resonators machined from single crystals of galium arsenide and silicon. In these experiments on high-frequency micromechanical resonators, designed to understand intrinsic mechanisms of dissipation, we explore dependence of dissipation on temperature, magnetic field, frequency, and size. In contrast to most of the previous measurements of acoustic attenuation in crystalline and amorphous structures in this frequency range, ours is a resonant measurement; dissipation is measured at the natural frequencies of structural resonance, or modes of the structure associated with flexural and torsional motion. In all our samples we find a weakly temperature dependent dissipation at low temperatures. We compare and contrast our data to various probable mechanisms, including thermoelasticity, clamping, anharmonic mode-coupling, surface anisotropy and defect motion, both in bulk and on surface. The observed parametric dependencies indicate that the internal defect motion is the dominant mechanism of intrinsic dissipation in our samples
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