A framework for community detection in heterogeneous multi-relational networks

There has been a surge of interest in community detection in homogeneous single-relational networks which contain only one type of nodes and edges. However, many real-world systems are naturally described as heterogeneous multi-relational networks which contain multiple types of nodes and edges. In this paper, we propose a new method for detecting communities in such networks. Our method is based on optimizing the composite modularity, which is a new modularity proposed for evaluating partitions of a heterogeneous multi-relational network into communities. Our method is parameter-free, scalable, and suitable for various networks with general structure. We demonstrate that it outperforms the state-of-the-art techniques in detecting pre-planted communities in synthetic networks. Applied to a real-world Digg network, it successfully detects meaningful communities.Comment: 27 pages, 10 figure

An experimental study of reinforced concrete beamcolumn joint with partially high strengthened longitudinal bar

It is necessary to generate the yield position away from the column face to minimize damage to the beam-column joint during a large earthquake in a reinforced concrete building. The same efficacy can be realized using partially high strengthened rebar. The number of longitudinal bars can be calculated for a bending moment smaller than the column face, reducing their number compared to the conventional bar-arrangement method. This paper describes reinforced concrete an interior beam-column subassemblage tests using this rebar as the longitudinal bars of beams and a column. The beam yield hinge was formed at a position apart from the column face, and the damage to the beam-column joint was less than the conventional bar-arrangement method. Additionally, the good performance was obtained if the bending strength of the column was large, even if the shear capacity margin of the beam-column joint was small. The column-beam flexural strength ratio and shear capacity margin at the beam-column joint need to be set with consideration of their relationship

Microscopic dissection of the process of stress granule assembly

AbstractStress granules (SGs) are mRNA triage sites that are formed in response to a variety of cellular stress. To study how SGs bring about the massive spatial compartmentalization, we monitored the localization of various RNA-binding proteins (RBPs) targeted to SGs upon exposure to stress. We discovered that concomitant with the onset of eIF2α phosphorylation, RBPs accumulate locally in the cytoplasm, which leads to increased inter-molecular interactions and the formation of robustly detergent-resistant foci. Subsequently, microtubules (MTs) mediate 1) the ordered spatial organization of SGs and 2) the recruitment of a set of nuclear-localized SG components to the cytoplasm. Meanwhile, MTs did not appear to be required for the maintenance of SG distribution after its assembly. Our data suggest that the process of SG formation is composed of MT-independent and -dependent pathways, which take place sequentially during stress response