Fundus topographical distribution patterns of ocular toxoplasmosis

BACKGROUND: To establish topographic maps and determine fundus distribution patterns of ocular toxoplasmosis (OT) lesions. METHODS: In this retrospective study, patients who presented with OT to ophthalmology clinics from four countries (Argentina, Turkey, UK, USA) were included. Size, shape and location of primary (1°)/recurrent (2°) and active/inactive lesions were converted into a two-dimensional retinal chart by a retinal drawing software. A final contour map of the merged image charts was then created using a custom Matlab programme. Descriptive analyses were performed. RESULTS: 984 lesions in 514 eyes of 464 subjects (53% women) were included. Mean area of all 1° and 2° lesions was 5.96±12.26 and 5.21±12.77 mm2, respectively. For the subset group lesions (eyes with both 1° and 2° lesions), 1° lesions were significantly larger than 2° lesions (5.52±6.04 mm2 vs 4.09±8.90 mm2, p=0.038). Mean distances from foveola to 1° and 2° lesion centres were 6336±4267 and 5763±3491 µm, respectively. The majority of lesions were found in temporal quadrant (p<0.001). Maximum overlap of all lesions was at 278 µm inferotemporal to foveola. CONCLUSION: The 1° lesions were larger than 2° lesions. The 2° lesions were not significantly closer to fovea than 1° lesions. Temporal quadrant and macular region were found to be densely affected underlining the vision threatening nature of the disease

Treatment of Patient With Papillon-Lefevre Syndrome With Short Dental Implants: A Case Report

Papillon-Lefevre syndrome (PLS) is an autosomal recessive disorder. Main features of PLS are hyperkeratosis of palms and soles concomitant with premature loss of primary and permanent dentition due to progressive periodontitis. Dental management of patients with PLS is usually challenging because of early excessive loss of alveolar bone support. We describe dental rehabilitation of a 34-year-old patient with PLS with severely atrophic mandible by means of 2 short (6 mm) dental implants between 2 mental foramina supporting an implant retained complete denture. After 1 year of follow-up period, the patient was doing well and there was no sign of bone resorption. In patients with PLS, dental osseointegrated implants (even with shorter lengths) can be safely used for atrophic mandibles instead of invasive preprosthetic applications such as bone augmentation, nerve lateralization, or alveolar distraction to avoid possible complications. (Implant Dent 2010;19:394-399

Osteomyelitis of the jaws

Üst veya alt çenede kemik infeksiyonu olan 23 hastada lezyonun özellikleri ve klinik belirtileri incelenmiştir. Osteomyelit iki hastada maksillada ve 21 hastada mandibulada yer almış olup 9'u post travmatik, 8'i odontojenik ve 6'sı post operatif Osteomyelit olarak sınıflandırılmıştır. Çoğu infeksiyonlar polimikrobiyal (%86) bulunmuş olup mandibuler osteoradyonekroz olguları bu çalışmaya dahil edilmemiştir. Tüm hastalarda osteomyelit kronik tip olup tedaviyi takip dönemleri altı hafta ile iki yıl arasında yer almıştır. Bu yazıda; hastalığın tanısı, etyolojisi, klinik ve radyolojik özellikleri, anatomik yerleşimi ve tedavisi değerlendirilmiştir.The presenting characteristics and clinical courses of 23 patients with upper and lower jaw bone infections are investigated. Two patients had the osteomyelitis in the maxilla and 21 in the mandible. Nine of the patients had post-traumatic osteomyelitis, eight had odontogenic osteomyelitis and six had post-operative osteomyelitis. Most infections were polymicrobial (86%). Cases with mandibular osleoradionecrosis were not included in this study. All of the patients had chronic osteomyelitis. The follow up period ranged from six weeks to two years. In this paper, diagnosis, etiology, clinical and radiological features, anatomical distribution and treatment of the lesions are reported

A FRAMEWORK FOR DETECTING COMPLEX EVENTS IN SURVEILLANCE VIDEOS

This paper presents a framework for detecting complex events in surveillance videos. Moving objects in the foreground are detected in the object detection component of the system. Whether these foregrounds are human or not is decided in the object recognition component. Then each detected object is tracked and labeled in the object tracking component, in which true labeling of objects in the occlusion situation is also provided. The extracted information is fed to the event detection component. Rule based event models are created and trained using Markov Logic Networks (MLNs) so that each rule is given a weight. Events are inferred using MLNs where the assigned weights are used to determine whether an event occurs or not. The proposed system can be applied to detect many complex events simultaneously. In this paper, detection of left object event is discussed and evaluated using PETS-2006, CANTATA and our dataset

The Turkish Hereditary Angioedema Pilot Study (TURHAPS): The First Turkish Series of Hereditary Angioedema

WOS: 000297278900014PubMed ID: 21832835Background: No published data presently exist concerning hereditary angioedema (HAE) in Turkey. The aim of the study was to initiate a preliminary multicentric evaluation about HAE and to determine the genetic properties of Turkish patients. Methods: Based on records drawn from four medical centers we identified a total of 70 subjects, belonging to 60 unrelated families, fulfilling clinical and laboratory criteria for diagnosis of HAE with Cl inhibitor deficiency. Ten type I patients, and their first-degree relatives, underwent genetic analysis for HAE. Results: The majority of patients were female (60%), the mean age was 37.7 +/- 14.1 years. The mean age at the time of first angioedema symptom was 12.5 +/- 9.2 years. Mean time lag between first symptom and diagnosis was 26 +/- 14.4 years. All but 3 subjects had HAE type I. Family history of angioedema was present in 75.7% of the cases. Cutaneous swelling was reported by 87.1% of the patients, facial edema by 65%, abdominal symptoms by 74.3% and approximately one half (55.7%) had experienced one or more laryngeal attack. Genetic analysis of 10 families demonstrated that 5 carried a mutation that had never been previously described. Conclusion: We found that the clinical features of Turkish HAE patients were consistent with previously described patterns of this rare disease. The most noteworthy feature identified in the study was a significantly long duration between the first symptom appearance and final diagnosis. Our detection of different mutations in 10 patients confirms the allelic heterogeneity of the disease. Copyright (C) 2011 S. Karger AG, BaselIstanbul UniversityIstanbul University [502/05052006]We wish to present our special thanks to Prof. Dr. Marco Cicardi who has peer reviewed the manuscript before submission. We wish to thank the patients and their family members who participated in this study. We also wish to thank Duzen Laboratories, Istanbul, Turkey, for allowing us the services of their DNA sequencer, ABI3130. This study was supported by the Istanbul University Research Fund, project No. 502/05052006

Fundus Topographical Distribution Patterns of Ocular Toxoplasmosis

Background: To establish topographic maps and determine fundus distribution patterns of ocular toxoplasmosis (OT) lesions.Methods: In this retrospective study, patients who presented with OT to ophthalmology clinics from four countries (Argentina, Turkey, UK, USA) were included. Size, shape and location of primary (1°)/recurrent (2°) and active/inactive lesions were converted into a two-dimensional retinal chart by a retinal drawing software. A final contour map of the merged image charts was then created using a custom Matlab programme. Descriptive analyses were performed.Results: 984 lesions in 514 eyes of 464 subjects (53% women) were included. Mean area of all 1° and 2° lesions was 5.96±12.26 and 5.21±12.77 mm2, respectively. For the subset group lesions (eyes with both 1° and 2° lesions), 1° lesions were significantly larger than 2° lesions (5.52±6.04 mm2 vs 4.09±8.90 mm2, p=0.038). Mean distances from foveola to 1° and 2° lesion centres were 6336±4267 and 5763±3491 µm, respectively. The majority of lesions were found in temporal quadrant (p<0.001). Maximum overlap of all lesions was at 278 µm inferotemporal to foveola.Conclusion: The 1° lesions were larger than 2° lesions. The 2° lesions were not significantly closer to fovea than 1° lesions. Temporal quadrant and macular region were found to be densely affected underlining the vision threatening nature of the disease.Keywords: Choroid; Imaging; Infection; Inflammation; RetinaFil: Hasanreisoglu, Murat. Koc University School of Medicine; Turquía. Gazi University School of Medicine; TurquíaFil: Halim, Muhammad Sohail. Ocular Imaging Research and Reading Center; Estados UnidosFil: Cakar Ozdal, Pinar. University of Health Sciences Ankara Ulucanlar Eye Training and Research Hospital; TurquíaFil: Ormaechea, Maria Soledad. Universidad Catolica de Las Misiones. Facultad de Cs. de la Salud; ArgentinaFil: Kesim, Cem. Universidad Nacional de Rosario. Facultad de Ciencias Médicas; ArgentinaFil: Ozdemir, Huseyin Baran. Universidad Austral. Hospital Universitario Austral. Departamento de Cirugía. Servicio de Oftalmologia.; ArgentinaFil: Uludag, Gunay. University of Stanford; Estados UnidosFil: Sredar, Nripun. University of Stanford; Estados UnidosFil: Cankurtaran, Mahmut. University of Health Sciences Ankara Ulucanlar Eye Training and Research Hospital; TurquíaFil: Liu, Xiaoxuan. University Hospitals Birmingham NHS Foundation Trust; Reino Unido. University Of Birmingham; . Moorfields Eye Hospital NHS Foundation Trust; Reino UnidoFil: Denniston, Alastair Keith. University Hospitals Birmingham NHS Foundation Trust; Reino Unido. University Of Birmingham; . Moorfields Eye Hospital NHS Foundation Trust; Reino UnidoFil: Rudzinski, Marcelo Nicolas. Universidad Catolica de Las Misiones; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Colombero, Daniel N.. Universidad Nacional de Rosario; ArgentinaFil: Schlaen, Bernardo Ariel. Universidad Austral. Hospital Universitario Austral; ArgentinaFil: Keane, Pearse Andrew. Moorfields Eye Hospital NHS Foundation Trust; Estados UnidosFil: Pavesio, Carlos. Moorfields Eye Hospital NHS Foundation Trust; Estados Unidos. University of Lincoln; Reino UnidoFil: Nguyen, Quan Dong. University of Stanford; Estados Unido