Ghar Wapsi and the ethics of conversion in India and other non-Abrahamic countries

The controversy over the Ghar Wapsi (homecoming) conversions in India has brought to focus the problematic ways in which freedom of (and from) religion and secularism have been idealized and enacted in the country since its independence. This paper looks at the state of discourse on conversion - especially the idea of predatory proselytization - and how Ghar Wapsi could compel both Christian and Muslim groups to re-examine the ways in which they convert non-Abrahamic populations. Borrowing from postcolonial frameworks, this paper seeks to problematize the idea of conversion itself in societies such as India - and why Ghar Wapsi is just as much a product of centuries of aggressive proselytizing and coercive conversion as it is a response to it

Advancements in Machine Learning for the Diagnosis of Chronic Kidney Disease

Chronic Kidney Disease (CKD) constitutes a significant global health issue, precipitating damage to the kidneys and stripping many individuals of their most productive years. Alarmingly, 40% of those affected by CKD remain oblivious to their condition, a stark contrast to many other diseases where early detection is more common. Unlike other conditions, CKD eludes cure unless identified promptly in its nascent stages. This research emphasizes the collection of critical indicators such as blood pressure and diabetes status to ascertain the presence of CKD in individuals. It proposes the employment of advanced machine learning techniques, including Random Forest, XGBoost, and Support Vector Machines, aiming to enhance early detection and thereby mitigate the disease's impact. Utilizing a CKD dataset, this study endeavors to predict the likelihood of CKD in individuals, offering a proactive approach to tackle this formidable health challenge

Fluoroscopy Assisted Minimally Invasive Transplantation of Allogenic Mesenchymal Stromal Cells Embedded in HyStem Reduces the Progression of Nucleus Pulposus Degeneration in the Damaged Interverbal Disc: A Preliminary Study in Rabbits

This study was conducted to develop a technique for minimally invasive and accurate delivery of stem cells to augment nucleus pulposus (NP) in damaged intervertebral discs (IVD). IVD damage was created in noncontiguous discs at L4-L5 level; rabbits (N=12) were randomly divided into three groups: group I treated with MSCs in HyStem hydrogel, group II treated with HyStem alone, and group III received no intervention. MSCs and hydrogel were administered to the damaged disc under guidance of fluoroscopy. Augmentation of NP was assessed through histological and MRI T2 mapping of the NP after eight weeks of transplantation. T2 weighted signal intensity was higher in group I than in groups II and III (P<0.05). Disc height index showed maximum disc height in group I compared to groups II and III. Histological score of the degenerative index was significantly (P<0.05) lower in group I (8.6 ± 1.8) than that in groups II (11.6 ± 2.3) and III (18.0 ± 5.7). Immunohistochemistry staining for collagen type II and aggrecan staining were higher in group I as compared to other groups. Our results demonstrate that the minimally invasive administration of MSCs in hyaluronan hydrogel (HyStem) augments the repair of NP in damaged IVD

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19

IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022). INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes. RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively). CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570

Glocal riddim: cultural production and territorial identity in Caribbean music videos

Over the past two decades, several musical genres have transcended their Caribbean origins to achieve global recognition and success. Among these are soca, dancehall and reggaeton, all forms that had been inextricably tied to native cultural expressions, but have become increasingly popular as global commodities, particularly as web-based streaming platforms (e.g. YouTube) enhance their global audiovisual mobility. Numerous artists within these genres have become internationally recognized superstars, and many of the most recent tracks reflect an increasing co-mingling with American ‘pop’ music, as record companies seek to invigorate mainstream sounds with these ‘exotic’, yet widely popular artists. This article explores representations of scalar territorial identity as articulated in music videos from within these genres so as to evaluate how identity intersects with profit-driven models applicable to the contemporary music industry. By evaluating imagery from a regionally representative sample of music videos, they identify the intimate relationship between identity, scale and cultural production. Ultimately, we interrogate how place-based identity is commodified in these representations and whether certain images are constructed more for transnational consumption than an articulation of a coherent local national, or regional identity

Oxygen deficiency induced nickel based oxides for UV & IR sensitive photo-conductive devices

Ni(NO3)(3)center dot 6H(2)O has been thermally decomposed to synthesize NiOx (0 < x < 1) and a modified citrate-nitrate route has been employed for LaNiO3-delta synthesis. These metal oxides have been characterized by XRD, SEM, TEM, XPS and UV-vis spectroscopy for the determination of their crystal structures, structural morphologies, oxidation states and optical band gaps. The devices, made of nanocrystalline-composites or nanocomposites, have been fabricated on gold coated soda lime glasses, where the device based on NiOx has been found applicable for UV photo-conducting and LaNiO3-delta has been recognized as a potential IR photo-conducting sensors. Their respective current amplifications have been recorded 8 and 2.2 times more than the dark current at 2 V of DC bias. The UV sensor has been explained by direct band gap semiconducting nature of NiOx and IR sensitivity of LaNiO3-delta was explained in terms oxygen deficiency induced band gap opening

A Review on Metal Binder Jetting 3D Printing

Binder jetting (BJ) is one of the major metal additive manufacturing (AM) technology used for the production of intricate metal components using a layer-by-layer approach. It belongs to the more general family of processes known as powder bed fusion procedures, in which a bed of metal powder is first selectively fused together with the help of a binder and then sintered in order to produce the final metal component. Binder Jetting is the sole non-fusion-based powder bed additive manufacturing technology; this means that, unlike laser-based AM procedures, the resulting parts are completely free of residual stresses. Small to medium batch production can be cost-effective due to lower tooling and setup expenses. This analysis focuses on the capacity of some of the most important engineering materials, including titanium, Inconel and stainless steel, to produce intricate geometries with a high degree of precision and accuracy. These materials find extensive use across many applications, including defence, industry, biomedical, aerospace, and other fields