Using Video Teaching Materials to Promote the Verbalization of Emotions and the Acquisition of Other People’s Perspectives in a Young Child with Behavioral Difficulties

The occurrences of pervasive developmental disabilities and a four-year-old boy’s fighting behavior over toys with his sibling were reduced by showing him video teaching materials intended to promote the verbalization of emotions and the acquisition of other people’s perspectives. The video teaching materials depicted a scene of the subject playing with his sibling. In the video, the subject says, “wait,” when his sibling tries to take away a toy he is playing with. We also inserted other lines into the narration, such as,“ when not using the toy, lending it to your sibling will make him or her happy.” During the intervention period after watching the video, the frequency of occurrences of fights over toys stabilized compared to that of the baseline period. However, the frequency of occurrences did not decrease, nor could we confirm the retention of the intervention effects. We did observe scenes in which the subject repeated lines from the video’s narration; however, due to instances such as one in which the sibling took away the toy even though the subject said, “wait,” we inferred that the subject was unable to accumulate enough successful experiences to retain the intervention effects

Parents Involvement in Their Child with Pervasive Developmental Disabilities

本研究の目的は、特別な支援を必要とする子どもを育てる親が、成長にともなって変化する子どもの行動や様子をどのように認識しているのかについて、認識変容モデルを生成することとした。特別な支援を必要とする子どもを育てる父母１組を対象に面接を実施し、出生から現在までの子どもの育ちと、育ちに対する思いについての語りを得た。修正版グラウンデッド・セオリー・アプローチを用いて語りを分析した結果、23個の概念から10個のカテゴリーを生成し、最終的に５個のカテゴリーグループを編成した。結果、認識は子どもの成長にともなって変容していくものの、なぜそのような行動をとるのだろうかと子どもの行動を解釈したり、課題を発見したり、子どもの成長や変化を感じたりすることについては、断続的に続けられていた。不安や子育てに対する徒労感は継続的に一定程度見られるものの、社会資源とのつながりにより、保護者の認識に変容が見られたことで、不安や徒労感が減少し、家族を含めた将来への展望が語られた。The purpose of this study was to create a model of recognition change to show how parents understands the behavior of children with pervasive developmental disabilities. Interviews were conducted with a parents of child with pervasive developmental disabilities, having them recount the state of their child from birth to the present day and their feelings about their child’s growth. After analyzing the content of the interview using the Modified grounded theory approach, 10 categories were generated from 23 concepts, which were ultimately compiled into 5 category groups. The results showed that the parents’ recognitions changed in accordance with the child’s growth. However, interpreting their child’s behavior （i.e., Why do the children take such a behavior?）, discovering issues, and realizing the growth of and changes in their child were continuously experienced. Although the parent has anxiety and psychological fatigue for the child care continuously, such feelings were seen to decrease as their connections with social resources changed the parents’ recognitions. Consequently, they recounted future prospects regarding their family

Screening of bacterial DNA in bile sampled from healthy dogs and dogs suffering from liver- or gallbladder-associated disease

Although the biliary system is generally aseptic, gallbladder microbiota has been reported in humans and some animals apart from dogs. We screened and analyzed the bacterial deoxyribonucleic acid in canine gallbladders using bile sampled from 7 healthy dogs and 52 dogs with liver- or gallbladder-associated disease. PCR screening detected bacteria in 17.3% of diseased dogs (9/52) and none in healthy dogs. Microbiota analysis of PCR-positive samples showed that the microbial diversity differed between liver- and gallbladder-associated disease groups. Thus, a specific bacterial community appears to occur at a certain frequency in the bile of diseased dogs

In-Stent Yellow Plaque at 1 Year After Implantation Is Associated With Future Event of Very Late Stent Failure The DESNOTE Study (Detect the Event of Very late Stent Failure From the Drug-Eluting Stent Not Well Covered by Neointima Determined by Angioscopy)

AbstractObjectivesThis study examined whether coronary angioscopy-verified in-stent yellow plaque at 1 year after drug-eluting stent (DES) implantation is associated with future event of very late stent failure (VLSF).BackgroundAtherosclerosis detected as yellow plaque by angioscopy has been associated with future events of acute coronary syndrome. Development of in-stent neoatherosclerosis is a probable mechanism of VLSF.MethodsThis study included 360 consecutive patients who received successful angioscopic examination at 1 year after implantation of a DES. They were clinically followed up for VLSF defined as cardiac death, acute myocardial infarction or unstable angina, or need for revascularization associated with the stent site.ResultsThe follow-up interval was 1,558 ± 890 days (4.3 ± 2.4 years). The incidence of VLSF was significantly higher in the patients with yellow plaque than in those without (8.1% vs. 1.6%; log rank p = 0.02). Multivariable analysis revealed the presence of yellow plaque (hazard ratio [HR]: 5.38; p = 0.02) and absence of statin therapy (HR: 3.25; p = 0.02) as risks of VLSF.ConclusionsIn-stent atherosclerosis evaluated by yellow plaque at 1 year after the implantation of DES and the absence of statin therapy were risks of VLSF. The underlying mechanism of VLSF appeared to be the progression of atherosclerosis as demonstrated by the yellow plaque

Big insulin-like growth factor 2-producing multiple solitary fibrous tumors treated with debulking surgery: A case report

BackgroundNon-islet cell tumor hypoglycemia (NICTH) is a rare paraneoplastic syndrome caused by a tumor-producing high molecular weight form of insulin-like growth factor 2 (IGF2) known as big IGF2. The only curative treatment for this condition is surgical resection of the responsible tumors. However, this may not be feasible in cases with multiple metastases at diagnosis of NICTH, and no standard treatment strategy for multiple tumors has been established. The effects of pharmacological therapies including somatostatin analogs are often inefficient and remain difficult to predict.Case descriptionA 68-year-old man was admitted to our hospital due to impaired consciousness and severe hypoglycemia. His medical history included diagnosis of a left temporal solitary fibrous tumor (SFT) at the age of 48 years, after which local recurrent and metastatic tumors were repeatedly resected. Four years before admission, multiple intraabdominal and subcutaneous tumors were detected and, being asymptomatic, were managed conservatively. Laboratory exam on admission demonstrated hypoglycemia accompanied with low serum insulin and IGF1 levels. Computed tomography (CT) scan revealed multiple intraabdominal and subcutaneous tumors increasing in size. Serum big IGF2 was detected on immunoblot analysis, and he was diagnosed as NICTH. In addition, tumor uptake was observed on 68Ga-labelled 1,4,7,10-tetraazacyclododecane-N,N’,N’’,N’’’-tetraacetic acid-d-Phe1-Tyr3-octreotide positron emission tomography/CT (DOTATOC-PET/CT). Since larger tumor is more suspicious about responsible producibility of big IGF2, we planned to resect large ones preferentially and reduce the amounts of residual tumors. Debulking surgery was performed by removing eleven intraabdominal tumors; the hypoglycemia was then completely corrected. Histological analyses revealed the resected tumors to be metastases of SFT having somatostatin receptor 2 expression. In immunoblot analysis, the resected tumors were found to be positive for big IGF2; serum big IGF2 was undetectable after surgery.ConclusionWe present a case of NICTH with multiple metastatic SFTs. We strategically performed debulking surgery, which led to remission of hypoglycemia. This result demonstrates a pioneering practical solution for NICTH cases with multiple tumors. In addition, in cases of SFTs presenting with NICTH, positivity of DOTATOC-PET/CT as well as single-dose administration of octreotide may be predictive of the efficacy of somatostatin-based therapy