Tuberous sclerosis complex (TSC) is an inherited genetic disorder
commonly associated with neuropsychiatric complications like epilepsy,
mental retardation, autism and other behavioral problems and
constitutes about 1-4% of the autistic population. Mental retardation
and seizures, particularly infantile spasms are significant risk
factors for the development of autism. Patients of TSC with autism are
more likely to have temporal tubers than those cases without autism. We
describe clinical and neuroimaging features of two such cases of
tuberous sclerosis with autism