Alterations in Serum SOD and CAT Levels in Patients with Breast Cancer

Breast cancers are potentially life-threatening malignancies in women. Development of cancer produces oxidative stress, which increases with disease progression. Hence, studies on antioxidants may be the most promising area of research for this clinical menace. We analysed serum superoxide dismutase (SOD), catalase (CAT) in women with breast cancer. The changes in the levels of serum superoxide dismutase and catalase are measured in breast cancer patients to assess the oxidative stress. A significant increase in the level of superoxide dismutase and a lower catalase activity was observed in all the three categories of breast cancer patients compared to normal individuals. The results suggested that high ROS production supports the oxidative stress in breast cancer. So, the treatment with antioxidants in the initial stages of the disease may be useful as secondary therapy

A NEW SPEECH ENHANCEMENT TECHNIQUE USING PERCEPTUAL CONSTRAINED SPECTRAL WEIGHTING FACTORS

This paper deals with musical noise result from perceptual speech enhancement type algorithms and especially wiener filtering. Although perceptual speech enhancement methods perform better than the non perceptual methods, most of them still return annoying residual musical noise. This is due to the fact that if only noise above the noise masking threshold is filtered then noise below the noise masking threshold can become audible if its maskers are filtered. It can affect the performance of perceptual speech enhancement method that process audible noise only. In order to overcome this drawback here proposed a new speech enhancement technique. It aims to improve the quality of the enhanced speech signal provided by perceptual wiener filtering by controlling the latter via a second filter regarded as a psychoacoustically motivated weighting factor. The simulation results shows that the performance is improved compared to other perceptual speech enhancement method

Clinical Evaluation of Oxidative Stress in Women with Breast Cancer

Breast cancers are potentially life-threatening malignancies in women. Development of cancer produces oxidative stress, which increases with disease progression. Hence, studies on antioxidants may be the most promising area of research for this clinical menace. We analysed serum Uric acid (UA) and Bilirubin (BR) in women with breast cancer. The changes in the levels of serum uric acid and bilirubin are measured in breast cancer patients to assess the oxidative stress. A significant increase in the levels of uric acid and an insignificant increase in the levels of bilirubin was observed in all the three categories of breast cancer patients compared to normal individuals. The results suggested that high ROS production supports the oxidative stress in breast cancer. So, the treatment with antioxidants in the initial stages of the disease may be useful as secondary therapy