45 research outputs found
Revisitando a "epistemologia social": esboço de uma ecologia sociotécnica do trabalho intelectual
Fora da ordem natural: a natureza nos discursos sobre a clonagem e a pesquisa com celulas-tronco em jornais brasileiros
Combination ledipasvir-sofosbuvir for the treatment of chronic hepatitis C virus infection: A and clinical perspective
Chronic hepatitis C treatment has continued to evolve, and interferon-free, oral treatment with direct-acting antiviral agents is the current standard of care. Recently, a new treatment, which is a combination of two direct-acting antiviral agents, ledipasvir 90 mg (anti-NS5A) and sofosbuvir 400 mg (anti-NS5B), has been approved in the US and the European Union for the treatment of chronic hepatitis C viral infection. In Phase III trials among chronic hepatitis C virus genotype 1 monoinfected (treatment-naïve, treatment-experienced, and with advanced liver disease or posttransplant) patients and HIV–hepatitis C virus coinfected patients, the ledipasvir-sofosbuvir fixed-dose combination is associated with a higher rate of sustained virologic response at 12 weeks after therapy has ceased. According to preliminary data, the ledipasvir-sofosbuvir combination also may be effective against hepatitis C genotype 4 virus infection. The ledipasvir-sofosbuvir combination taken orally is generally well-tolerated. Moreover, the combination treatment may suppress the effect of predictive factors of chronic hepatitis C that have historically been known to be associated with treatment failure. Thus, the fixed-dose single-tablet combination of ledipasvir-sofosbuvir offers a new era for the effective treatment of a variety of patients suffering from chronic hepatitis C virus infection.SCOPUS: re.jinfo:eu-repo/semantics/publishe
Teaching democracy to young people
Le document analyse les résultats d'une série d'entretiens menés auprès des enseignants du secondaire sur la meilleure façon d'apprendre la démocratie aux élèves. Il fait le point sur les thématiques qui paraissent essentielles aux enseignants mais aussi sur le rôle spécifique qu'ils attrribuent à l'école et sur les méthodes pédagogiques à utilise
Communes mesures
Une analyse sociologique des principales communes de l'arrondissement liégeois, découpée en chapitres pour être publiée sous forme d'articles dans le quotidien "La Wallonie
Wallonia through six town portraits
A la demande du quotidien "La Wallonie", une enquête a été réalisée auprès des habitants des six principales villes Wallonnes. A chaque fois, le questions portaient sur l'identité wallonne, l'identité communale, mais aussi sur la perception des politiques locales, des institutions et autorités communales