Balloon dilatation of cicatricial bladder neck contracture: evaluation of the efficacy after transurethral prostate interventions (preliminary results)

Introduction. Cicatricial bladder neck contracture (CBNC) is one of the most common complications after endoscopic prostate procedures. There is no consensus among urologists about which method is advisable to use in the treatment of postoperative CBNC — transurethral resection (TUR) or incision. In this regard, the study of balloon dilation is a promising alternative.Purpose of the study. To improve the results of balloon dilation in patients with CBNC after endoscopic surgery for BPH.Materials and methods. The study involved 34 patients with recurrent CBNC after TUR and laser enucleation. The patients were divided into 2 groups: group A (n = 16) included men who, after bladder neck's TUR, additionally underwent transurethral balloon dilatation, while control group B (n = 18) included men who were prescribed conservative therapy only using alpha-blockers.Results. 2 months after the bladder neck's TURP and 1 month after balloon dilatation in group A, the mean IPSS score was 14.2 ± 2.1, QoL was 2.9 ± 0.9, while in group B it was at the end of 2nd month after the bladder neck's TURP, these indicators were 16.2 ± 3.1 and 3.9 ± 0.8 points, respectively (p <0.05). The average maximum urine flow rate in group A was 15.8 ± 2.8 ml/sec, in group B was 11.6 ± 2.8 ml/sec (p <0.05). Also, a significant decrease in the residual urine volume was revealed from 43.4 ± 34.4 to 27.8 ± 12.5 ml in group A, while in group B this indicator decreased from 49.1 ± 30.2 to 30.2 ± 11.7 ml.Conclusions. The method of transurethral balloon dilatation in case of CBNC under TRUS control using local anaesthesia only avoids gross trauma to the urethra and bladder neck with a cystoscope or mechanical dilatator. It helps to reduce the likelihood and severity of complications of this treatment method

Endoscopic treatment for bulbar-membranous urethral obliteration: evaluation of the efficacy and safety

Introduction. The problem of endoscopic treatment for urethral strictures and obliterations remains unresolved. It is necessary to note that the effectiveness depends not only on the right indications, but also on the surgical technique and the study of the postoperative period management.Objective. To evaluate the efficacy and safety of endoscopic treatment of patients with bulbar-membranous urethral obliteration.Materials and methods. The study included 103 patients aged 20 to 89 years with bulbar-membrane urethral obliteration, who, for some reason or another, cannot perform urethroplasty. The patients underwent endoscopic recanalization of the urethra under X-ray control with further circular transurethral electroresection (TUR) of the scar tissues in the urethral obliteration zone (after 6 – 7 days).Results. The average age of the patients was 61.1 ± 18.3 years. After the operation, self-urination was restored in all patients. The average maximum urine flow rate (Q max) before discharge from the hospital was 12.6 ± 0.5 ml/s. Throughout the follow-up period, Q max tended to increase and at the end of the study (36 months) reached values of 16.5 ± 0.5 ml/s. During the first year of follow-up, 18 (17.5%) patients developed recurrent urethral stricture. Seventeen (16.5%) patients underwent repeated circular TUR of scar tissue in the zone of recurrent stricture. The effectiveness of the treatment was 90.0%.Conclusion. Endoscopic urethral recanalization followed by TUR of scar tissue in the obliteration zone is an effective and safe method in the treatment of bulbar-membranous urethral obliteration with length less than 1.0 cm

Gravity in a stabilized brane world model in five-dimensional Brans-Dicke theory

Linearized equations of motion for gravitational and scalar fields are found and solved in a stabilized brane world model in five-dimensional Brans-Dicke theory. The physical degrees of freedom are isolated, the mass spectrum of Kaluza-Klein excitations is found and the coupling constants of these excitations to matter on the negative tension brane are calculated.Comment: 12 pages, LaTe

Estimation of the Efficacy of Retroperitoneoscopic Renal Cysts Deroofing

Introduction. The intensive introduction of modern endovideosurgical techniques creates the prerequisites for the further expansion of minimally invasive surgical interventions. Literature reviews` data on the results of retroperitoneoscopic operations suggest that endovideosurgery in urology has broad prospects for further development.Purpose of the study. To estimate of the efficacy and safety of the retroperitoneoscopic operations for renal cysts.Materials and methods. Retroperitoneoscopic operations (renal cysts deroofing) were performed for 152 symptomatic patients with Bosniak I kidney cysts (from 4.4 х 3.8 cm to 14.5 х 14.0 cm). Proposal of the operations were classified according to the technical difficulty as “Easy” in 147 (96.7%) cases (Е: sum of scores 3-5), in 5 (3.3%) cases – «Slightly difficult» (SD: score 7). Statistical analyses of the results performed by the program Microsoft Office Excel 2007, StatSoft Statistica 8.0 with using the Student-Fisher`s criteria.Results. The mean duration of the operations was 35.7 ± 6.1 min (30-90 min); there were not any intraoperative complications; the mean blood loss was 23.0 ± 4.1 ml (10-100 ml); there was no need for blood transfusion; incidence of postoperative complications were 2.4% - in 4 cases there were manifestation of urinary tract infection during the postoperative period (II category of the complications according to Clavien-Dindo classification); mean hospital stay was 2.2 ± 0.1 day (1-6 days); drainages were removed on second postoperative day; there were not any conversions to open operations and additional procedures in postoperative period.Conclusions. Retroperitoneoscopic renal cysts deroofing is effective and safe procedure for the treatment of simple kidney cysts. This method has the advantages of minimal invasiveness, minimal complications, short in hospital stay and fast recovery of the patients.The study did not have sponsorship. The authors have declared no conflicts of interest