19 research outputs found

    Primi rilievi sul glicocalice delle cellule epiteliali del colon in condizioni normali e in soggetti affetti da colite ulcerosa.

    No full text

    The glycocalix of the epithelial cells of the colon, observed in normal and ulcerous colitic conditions.

    No full text
    Biopsies of subjects affected by ulcerous colitis were stained with ruthenium Red. Alterations of the cellular coat and glycocalyx of the epithelial cells of the colon were identified

    BCR/ABL genes and leukemic phenotype: from molecular mechanisms to clinical relation.

    No full text

    Quantification of Imatinib Plasma Levels in Patients with Chronic Myeloid Leukemia: Comparison Between HPLCUV and LCMS/MS

    No full text
    Measurement of imatinib plasma concentration can be useful to evaluate patient adherence to daily oral therapy, potential drug–drug interaction, treatment efficacy, and severe drug-related adverse events. The aim of this study was to correlate the two different blood level test methods, HPLC–UV and LC–MS/MS. We analyzed 162 plasma samples from patients treated with imatinib. We estimated the correlation between the two analytical methods on total data set and on five sets of patients grouped into different categories based on the drug-dose therapy. Finally, imatinib quantification was correlated with genetic data on the molecular response in monitoring follow-up of CML patients
    corecore