Work-Family Conflict and Unethical Pro-family Behavior: The Mediating Effect of Threat Appraisal and the Moderating Effect of Family Collectivism Orientation

Unethical pro-family behavior (UPFB) is prevalent in organizations and has adverse effects on organizations, but very few studies have examined the factors that lead to UPFB. We use a cognitive appraisal theoretical framework to argue that employees’ unethical pro-family (UPFB) behavior results from work and family conflicts (WFC/FWC) are mediated by threat appraisal and moderated family collectivism orientation. Based on the questionnaire data of 496 full-time employees from two-time points, we found that WFC/FWC was positively correlated with UPFB where threat appraisal played a mediating role in this relationship; Family collectivism orientation strengthens the threat appraisal-UPFB relationship and the mediation relationship between WFC/FWC and UPFB via threat appraisal. These findings offer an understanding of the theoretical and practical implications which could help organizations reduce UPFB. Finally, we discuss possible directions for future research

Simultaneous Extraction and Identification of Phenolic Compounds in Anoectochilus roxburghii Using Microwave-Assisted Extraction Combined with UPLC-Q-TOF-MS/MS and Their Antioxidant Activities

This study used MAE and RSM to extract phenolic compounds from Anoectochilus roxburghii, and the optimum conditions defined by the model to give an optimum yield of 1.31%. The antioxidant activity in vitro showed when the concentration of phenolic compounds was reached 1 mg mL-1, the clearance rates were 82.58% for DPPH and 97.62% for ABTS+. In vivo antioxidant experiments used D-galactose to build oxidative damage in healthy Kunming mice. The result showed that the extractions of A. roxburghii can improve the antioxidant ability and the medium and low dose groups had better ability to scavenge free radicals. The UPLC-Q-TOF-MS/MS was developed to identify 21 kinds of phenolic compounds by molecular mass, ms/ms fragmentation, as well as retention time. The result showed that the phenolic compounds of A. roxburghii had significant potential as a natural antioxidant to promote health and to reduce the risk of disease

Clues to Evolution of the SERA Multigene Family in 18 Plasmodium Species

SERA gene sequences were newly determined from 11 primate Plasmodium species including two human parasites, P. ovale and P. malariae, and the evolutionary history of SERA genes was analyzed together with 7 known species. All have one each of Group I to III cysteine-type SERA genes and varying number of Group IV serine-type SERA genes in tandem cluster. Notably, Group IV SERA genes were ascertained in all mammalian parasite lineages; and in two primate parasite lineages gene events such as duplication, truncation, fragmentation and gene loss occurred at high frequency in a manner that mimics the birth-and-death evolution model. Transcription profile of individual SERA genes varied greatly among rodent and monkey parasites. Results support the lineage-specific evolution of the Plasmodium SERA gene family. These findings provide further impetus for studies that could clarify/provide proof-of-concept that duplications of SERA genes were associated with the parasites' expansion of host range and the evolutionary conundrums of multigene families in Plasmodium

Development of an obesity-related multi-gene prognostic model incorporating clinical characteristics in luminal breast cancer

Summary: Despite adjuvant chemotherapy and endocrine therapy in luminal breast cancer (LBC), relapses are common. Addressing this, we aim to develop a prognostic model to refine adjuvant therapy strategies, particularly for patients at high recurrence risk. Notably, obesity profoundly affects the tumor microenvironment (TME) of LBC. However, it is unclear whether obesity-related biological features can effectively screen high-risk patients. Utilizing weighted gene coexpression network analysis (WGCNA) on RNA sequencing (RNAseq) data, we identified seven obese LBC genes (OLGs) closely associated with patient prognosis. Subsequently, we developed a luminal obesity-gene clinical prognostic index (LOG-CPI), combining a 7-gene signature, TNM staging, and age. Its predictive efficacy was confirmed across validation datasets and a clinical cohort (5-year accuracy = 0.828, 0.760, 0.751, and 0.792, respectively). LOG-CPI emerges as a promising predictor for clinical prognosis and treatment response, helping distinguish molecular and immunological features in LBC patients and guiding clinical practice by identifying varying prognoses

Особенности субъективного благополучия и самореализации менеджеров среднего звена : магистерская диссертация по направлению подготовки: 37.04.01 - Психология

The methanol to olefins (mto) reaction was performed over zsm-5 zeolite at 300 degrees c under various methanol weight hourly space velocity (whsv) values. during these trials, the catalytic perfor mance was assessed, in addition to the formation and function of organic compounds retained in the zeolite. analysis of reaction effluents and confined organics demonstrated a dual-cycle reaction mechanism when employing zsm-5. the extent of the hydrogen transfer reaction, a secondary reaction in the mto process, varied as the catalyst-methanol contact time was changed. in addition, c-12/c-13-methanol switch experiments indicated a relationship between the dual-cycle mechanism and the extent of the hydrogen transfer reaction. reactions employing a low methanol whsv in conjunction with a long contact time favored the hydrogen transfer reaction to give alkene products and promoted the generation and accumulation of retained organic species, such as aromatics and methylcyclopentadienes, which enhance the aromatic cycle. when using higher whsv values, the reduced contact times lessened the extent of the hydrogen transfer reaction and limited the generation of methylcyclopentadienes and aromatic species. this suppressed the aromatic cycle, such that the alkene cycle became the dominant route during the mto reaction. (c) 2016, dalian institute of chemical physics, chinese academy of sciences. published by elsevier b.v. all rights reserved

Methanol conversion on ZSM-22, ZSM-35 and ZSM-5 zeolites: effects of 10-membered ring zeolite structures on methylcyclopentenyl cations and dual cycle mechanism

ZSM-22, ZSM-35 and ZSM-5, aluminosilicate zeolites possessing 10-membered ring channels, have been used in the present study as the catalysts of the MTO reaction. The diversities in dimensions and connection types of the 10-membered ring channels of the three zeolite catalysts make their performances in the MTO reaction quite different. As the key active species involved in the hydrocarbon-pool mechanism in the MTO reaction, methylcyclopentenyl cations (MCP+) and methylbenzenes have been captured by C-13 MAS NMR and GC-MS over the three zeolite catalysts during methanol conversion. The comparative studies of the retained organics generation over the zeolite catalysts indicate that due to the spatial confinement effects of the inorganic frameworks, the retained organic species generated in the catalysts during the MTO reaction are influenced by both their sizes and amounts. A detailed analysis of the confined organic species showed the formation of MCP with varied methyl substitutions over the three zeolites. C-12/C-13-methanol switch experiments were employed to investigate the reaction route for product generation. The differences in the participation levels of the methylbenzene and methylcyclopentadiene over the three zeolite catalysts imply that the formation and function of the organic species formed in the 10-membered ring channel were impacted by the chemical environment of the zeolites, and the methanol conversion that occurred in the 10-membered ring channels of the three zeolites also followed different reaction routes