Comparison of High Fiber and Low Carbohydrate Diets on Owner-Perceived Satiety of Cats During Weight Loss

Food-seeking behaviors exhibited by cats during weight loss programs are frustrating to owners. Two categories of therapeutic weight loss diets are available for cats: High Fiber (HF) and Low Carbohydrate (LC). The objective of this study was to determine if cat owners perceive a difference in satiety when their cats are fed either a HF or LC diet during a weight loss regimen. Twenty-eight client-owned cats were randomly assigned to either an HF or LC canned diet and fed to 80% of their ideal weight resting energy requirements. Cats were rechecked at 2, 4, 6 and 8 weeks and food intake adjusted to maintain weight loss between 0.5-1% per week. Seventeen cats completed the 8-week weight loss study (HF = 10, LC = 7). Owners completed behavior questionnaires at each visit and were blinded to food assignments. The two diet groups did not differ significantly by age, sex, body condition score, caloric intake, or rate of weight loss during the study. The two diets did not differ by owner response to questionnaire. In conclusion, owners perceived cats to be equally satiated during weight loss regimens on both the HF and LC diets

Clinicopathologic and gastrointestinal effects of administration of prednisone, prednisone with omeprazole, or prednisone with probiotics to dogs: A double‐blind randomized trial

Abstract Background The efffect of administering of probiotics or twice‐daily omeprazole on glucocorticoid‐induced gastric bleeding in dogs is unknown. Hypothesis Compare gastrointestinal bleeding among dogs administered placebo, prednisone (2 mg/kg q24h), prednisone with omeprazole (1 mg/kg q12h), or prednisone with probiotics (Visbiome, 11.2‐22.5 billion CFU/kg q24h) for 28 days. Animals Twenty‐four healthy research dogs. Methods Double‐blinded, placebo‐controlled randomized trial. Clinical signs and endoscopic gastrointestinal mucosal lesion scores at baseline (t1), day 14 (t2), and day 28 (t3) were compared using split‐plot repeated‐measures mixed‐model ANOVAs. Results Fecal score differed by treatment‐by‐time (F[6,40] = 2.65, P < .03), with higher scores in groups receiving prednisone at t3 than t1. Nineteen of thirty‐three episodes of diarrhea occurred in the prednisone with omeprazole group. Gastric mucosal lesion scores differed by treatment‐by‐time (F[6,60] = 2.86, P = .05), among treatment groups (F[3,60] = 4.9, P = .004), and over time (F[2,60] = 16.5, P < .001). Post hoc analysis revealed lesion scores increased over time for all groups receiving prednisone. At t3, scores for the prednisone (8.7 ± 4.9) and prednisone with probiotics (8.7 ± 4.9) groups differed significantly from placebo (1.8 ± 1.8; P ≤ .04), whereas scores for the prednisone with omeprazole (6.5 ± 5.5) group did not differ from placebo (P = .7). Ulcers occurred only in dogs receiving prednisone. Conclusions and Clinical Importance Prednisone‐induced gastric bleeding. Co‐administration of omeprazole partially mitigated bleeding, but a similar protective benefit was not demonstrated by co‐administration of the evaluated probiotic

Prevalence of asymptomatic urinary tract infections in morbidly obese dogs

Background. Obesity has reached epidemic proportions in dogs and, as in humans, cost of care has increased due to associated comorbidities. In humans, asymptomatic urinary tract infections (UTI) may be more prevalent in the obese. Asymptomatic bacteriuria (AB) is the term used when UTI are asymptomatic. We hypothesized that morbidly obese dogs are similarly more likely to have asymptomatic bacteriuria than lean, overweight, and moderately obese dogs. Methods. A retrospective study was undertaken to explore a possible association between obesity and asymptomatic bacteriuria. Records from lean, overweight, and obese dogs receiving both a dual energy absorptiometry (DXA) scan and urine culture were included. Results. Six positive urine cultures were identified among 46 dogs fulfilling search criteria. All six positive cultures were found in dogs with body fat percentage of >45%. In dogs with body fat percentage of <45%, there were no positive urine cultures. Discussion. There was an increased prevalence of asymptomatic bacteriuria in the morbidly obese dogs in this study compared to those that were lean, overweight, or moderately obese. Whether antibiotic therapy is necessary in such cases is still being debated, but because asymptomatic bacteriuria may be associated with ascending infections, uroliths, or other complications, the data reported herein support the screening of obese patients for bacteriuria