4 research outputs found
Prospectus, September 28, 2016
PARKLAND SURGICAL TECHNOLOGY ON CUTTING EDGE; Humans of Parkland: Michelle Wright; Police: 5 shot, 1 dead, after fight at Illinois campus party; Food pantry helps Parkland students; People around the world react to first Trump-Clinton debate; The Pledge, the national anthem, patriotism; Pygmalion highlights from 2016; Call for Entries for the 2016 CUDO PRO SHOWhttps://spark.parkland.edu/prospectus_2016/1023/thumbnail.jp
Prospectus, October 12, 2016
PARKLAND OFFERS DEPRESSION SCREENINGS; Meet the Staff: Kelly Youngblood; Seamus Reilly; Vice President for Institutional Advancements, Irish singer; Survey, Mapping Career Fair set for Oct. 20; Clown hysteria spreading, Illinois not immune; Pennies for Pumpkins 2016; Parkland police stress safety for campus; Prospectus editor visits Bloomington Zoo; Notice to faculty, students regarding final exams; Prospectus staff attends Illinois Community College Journalism Association Conferencehttps://spark.parkland.edu/prospectus_2016/1024/thumbnail.jp
Guidelines for Diagnosis and Management of Infective Endocarditis in Adults: A WikiGuidelines Group Consensus Statement.
IMPORTANCE
Practice guidelines often provide recommendations in which the strength of the recommendation is dissociated from the quality of the evidence.
OBJECTIVE
To create a clinical guideline for the diagnosis and management of adult bacterial infective endocarditis (IE) that addresses the gap between the evidence and recommendation strength.
EVIDENCE REVIEW
This consensus statement and systematic review applied an approach previously established by the WikiGuidelines Group to construct collaborative clinical guidelines. In April 2022 a call to new and existing members was released electronically (social media and email) for the next WikiGuidelines topic, and subsequently, topics and questions related to the diagnosis and management of adult bacterial IE were crowdsourced and prioritized by vote. For each topic, PubMed literature searches were conducted including all years and languages. Evidence was reported according to the WikiGuidelines charter: clear recommendations were established only when reproducible, prospective, controlled studies provided hypothesis-confirming evidence. In the absence of such data, clinical reviews were crafted discussing the risks and benefits of different approaches.
FINDINGS
A total of 51 members from 10 countries reviewed 587 articles and submitted information relevant to 4 sections: establishing the diagnosis of IE (9 questions); multidisciplinary IE teams (1 question); prophylaxis (2 questions); and treatment (5 questions). Of 17 unique questions, a clear recommendation could only be provided for 1 question: 3 randomized clinical trials have established that oral transitional therapy is at least as effective as intravenous (IV)-only therapy for the treatment of IE. Clinical reviews were generated for the remaining questions.
CONCLUSIONS AND RELEVANCE
In this consensus statement that applied the WikiGuideline method for clinical guideline development, oral transitional therapy was at least as effective as IV-only therapy for the treatment of IE. Several randomized clinical trials are underway to inform other areas of practice, and further research is needed
Guidelines for Diagnosis and Management of Infective Endocarditis in Adults: A WikiGuidelines Group Consensus Statement.
IMPORTANCE: Practice guidelines often provide recommendations in which the strength of the recommendation is dissociated from the quality of the evidence.
OBJECTIVE: To create a clinical guideline for the diagnosis and management of adult bacterial infective endocarditis (IE) that addresses the gap between the evidence and recommendation strength.
EVIDENCE REVIEW: This consensus statement and systematic review applied an approach previously established by the WikiGuidelines Group to construct collaborative clinical guidelines. In April 2022 a call to new and existing members was released electronically (social media and email) for the next WikiGuidelines topic, and subsequently, topics and questions related to the diagnosis and management of adult bacterial IE were crowdsourced and prioritized by vote. For each topic, PubMed literature searches were conducted including all years and languages. Evidence was reported according to the WikiGuidelines charter: clear recommendations were established only when reproducible, prospective, controlled studies provided hypothesis-confirming evidence. In the absence of such data, clinical reviews were crafted discussing the risks and benefits of different approaches.
FINDINGS: A total of 51 members from 10 countries reviewed 587 articles and submitted information relevant to 4 sections: establishing the diagnosis of IE (9 questions); multidisciplinary IE teams (1 question); prophylaxis (2 questions); and treatment (5 questions). Of 17 unique questions, a clear recommendation could only be provided for 1 question: 3 randomized clinical trials have established that oral transitional therapy is at least as effective as intravenous (IV)-only therapy for the treatment of IE. Clinical reviews were generated for the remaining questions.
CONCLUSIONS AND RELEVANCE: In this consensus statement that applied the WikiGuideline method for clinical guideline development, oral transitional therapy was at least as effective as IV-only therapy for the treatment of IE. Several randomized clinical trials are underway to inform other areas of practice, and further research is needed