Hatched: The capacity for sustainable development

Hatched: The capacity for sustainable development is edited by Landcare Research scientists Bob Frame, Richard Gordon and Claire Mortimer and is a collection of research findings, stories and tools exploring five key areas of capacity required for New Zealand’s long-term success. It covers innovative research undertaken with businesses, across policy sectors, communities and individuals and was funded by the Foundation for Research, Science and Technology

An exploratory study on the perceived prevalence and effect of sexual attraction in the South African workplace

South African organisations face increasing diversification of the workforce, with the concomitant benefits and potential challenges thereof. Along with the traditional approaches towards the management of diversity, less conventional areas have yet to be explored within the South African context. One such area is that of sexual attraction in the workplace. With the growing need for organisations to become employers of choice, to create organisational competitive advantage and optimally leverage their human capital it is becoming evident that acknowledgment of innate humanity is essential. The question under exploration was to determine what the perceptions surrounding the prevalence and effects of sexual attraction in the South African workplace are. Employees are human beings, human beings are essentially sexual in nature and therefore it can be said that sexuality and all its composite elements are present in and acting upon organisations. The researcher focused exclusively on self-reported perceptions and experiences surrounding this phenomenon in the workplace, including its perceived effects on productivity; communication; job performance; job involvement; job satisfaction, stress; sexual harassment; morale; the individual and the workgroup. In addition the perceived roles of management in regulating sexual attraction as well as potential perceived motives underlying its initiation in organisations were also explored. The research explored and described differences with regards to these areas of organisational life in respect of age groups; gender; marital status; relationship status; experience of sexual attraction; awareness of sexual attraction and workplace rendezvous experiences. A self-administered questionnaire was designed specifically for the study by the researcher and was used to gain feedback from 155 respondents in numerous fields and organisations through a mixed methods sampling technique. Analysis of data was statistical in nature, including detailed descriptive or frequency distributions; correlations and inferential statistics. The research yielded substantial results with regards to perceptions of sexual attraction in the South African workplace, with numerous implications for management and Human Resource practitioners abounding. Sexual attraction in the workplace is perceived to be a prevalent organisational condition amongst respondents with findings revealing that it is viewed as inevitability in the workplace. Personal experience of sexual attraction was alluded to by the majority of respondents. In addition, various organisational factors, such as proximity, similarity and ongoing work requirements were confirmed as having a perceived influence on the prevalence of sexual attraction amongst co-workers. This linked with findings and existing research with regards to aspects of diversity in the workplace, particularly similarity of moral values. In line with the body of literature, elements underlying sexual attraction were divergent, indicating that attraction is individual specific. Younger respondents indicated that they found physical elements of their co-workers attractive, which was less the case for the older respondent group. When evaluating findings on the perceived effects of sexual attraction in the workplace it was evident that respondents felt that sexual attraction had a slight positive effect on productivity. Significant differences were observed between age groups as well as personal experience of sexual attraction on this construct. Interestingly, sexual attraction was perceived to have a positive effect on job involvement by respondents, with differences observed due to age groups and amongst individuals whom had been previously sexually attracted to a colleague and those whom had not. Gender differences were also observed herein, with females having higher perceived positive effects on job involvement. Job satisfaction was perceived to be positively affected by sexual attraction in the workplace by respondents. Significant differences between age groups as well as with regards to marital statuses and relationship statuses were also found with regards to this construct. Mixed perceptions existed around the influence of sexual attraction on the experience of stress, with a respondents age group found to have an influence thereon. In addition thereto, a respondent’s marital status also made a difference in this regard. Generally the findings concurred with the available literature on the topic. Moreover, the general affects of sexual attraction on the individual involved in this workplace dynamic were fairly positively perceived by respondents. This finding was evidenced to be influenced to some extent by respondents’ experience of prior sexual attraction to a colleague; age; relationship status and marital status. The latter was found to have the largest influence in this regard. Sexual attraction was perceived by respondents to have a negative effect on communication and job performance. The perception of the latter was found to be significantly different between individuals whom had been aware of sexual attraction in the workplace and those whom had not indicated that this was the case; as well as with respondents whom reported prior sexual attraction to a colleague having higher perceived positive influences thereof on job performance. Age was also found to be an influential factor on perceptions surrounding job performance. Morale was found to be slightly negatively affected due to sexual attraction according to reported perceptions of respondents. The majority of respondents were inclined to feel that sexual harassment is an important organisational issue, yet the effects of sexual attraction thereupon may not be as negative as one might have thought. Prior sexual attraction to a colleague was found to have an influence on respondent perceptions of sexual harassment, as did the length of marriage for married respondents. Most respondents perceived sexual attraction to have more of a negative effect on the workgroup surrounding the sexually attracted individuals. Influencing variables in this regard were respondent age and marital status. In addition, motives underlying sexual attraction were negatively perceived by respondents. Marital status was found to have an influence on respondent perceptions of sexual attraction motives. Findings revealed that respondents in general felt that management has some form of role to play in the regulation of this workplace dynamic. However, the vast majority of respondents felt that it was the responsibility of the individual employee to manage their own sexual attraction in the workplace. Differences in this perception were found between males and females; age groups as well as the length of marriages of married respondents. The research established that sexual attraction is a prevalent condition in South African organisations. Moreover, substantial effects of sexual attraction were reported on various important areas of organisational functioning. Copyright 2009, University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. Please cite as follows: Mortimer, C 2009, An exploratory study on the perceived prevalence and effect of sexual attraction in the South African workplace, MCom dissertation, University of Pretoria, Pretoria, viewed yymmdd C12/4/203/gmDissertation (MCom)--University of Pretoria, 2009.Human Resource Managementunrestricte

Battleaxes, spinsters and chars: the ageing woman in British film comedy of the mid-twentieth century

‘Battleaxes, Spinsters and Chars: the Ageing Woman in British Film Comedy of the Mid-Twentieth Century’ explores the prominence of the mature woman in British film comedies of the mid-twentieth century, spanning the period from the Second War World to the mid-1960s. This thesis is structured around case studies featuring a range of film comedies from across this era, selected for the performances of character actresses who were familiar faces to British cinema audiences. Organised chronologically, each chapter centres around films and actresses evoking specific typologies and themes relevant to female ageing: the ‘immobile’ woman in wartime, the spinster in the post-war era, retirement and old age in the 1950s, and the cockney matriarch in the early 1960s. The selection of case studies encompasses the overlooked and critically derided alongside the more celebrated and better known in order to represent the range of British film comedy of the time. The final chapter spans the time-frame of the whole thesis, exploring the later life stardom of Margaret Rutherford. The thesis is centred on close textual analysis of sequences from the case studies, applying research into a range of historical texts relevant to the films and actresses, including biographies, letters, correspondence, press, posters and publicity materials. Each chapter draws on diverse scholarly disciplines to interrogate representations of female ageing, encompassing age studies, feminist studies, star studies, sociological research, genre studies, political philosophy, anthropology and social history. I conclude that film comedy of the mid-twentieth century offered familiar and reassuring typologies of the ageing woman for audiences in a time of upheaval and social change. My analysis of the films demonstrates how the representations of female ageing provided by these character actresses and stars were inflected by the cultural and social context. In her various guises the character actress in British comedy offered a fantasy of continuity, stability and reassurance within a country which struggled to define its national identity, and a national cinema which was struggling to survive

Expression of an anti-CD4 single-chain antibody fragment from the donor cornea can prolong corneal allograft survival in inbred rats

To investigate whether expression of an anti-CD4 antibody fragment (scFv) by a lentivector-transduced donor cornea can prolong rat corneal allograft survival. Methods Inbred Fischer 344 rats received penetrating corneal allografts from Wistar-Furth donors after a 3 h transduction of the donor cornea with a lentivector carrying anti-CD4scFv cDNA (Lv-CD4scFv), a lentivector carrying the reporter gene-enhanced yellow fluorescence protein (LV-eYFP), or an adenoviral vector carrying anti-CD4 scFv cDNA (Ad-CD4scFv). Unmodified controls were also performed. Graft survival was assessed by corneal clarity, and rejection was confirmed histologically. Results In organ-cultured corneas, expression of anti-CD4 scFv was detected at 2 days post-transduction with the adenoviral vector, compared with 5 days post-transduction with the lentivector, and was 10-fold higher than the former. More inflammation was observed in Ad-CD4scFv-modified allografts than in Lv-CD4scFv-modified grafts at 15 days postsurgery (p=0.01). The median time to rejection for unmodified, LV-eYFP and Ad-CD4scFv grafts was day 17, compared with day 22 for Lv-CD4scFv grafts (p≤0.018). Conclusion Donor corneas transduced with a lentiviral vector carrying anti-CD4scFv cDNA showed a modest but significant prolongation in graft survival compared with unmodified, Lv-eYFP and Ad-CD4scFv grafts. However, rejection still occurred in all Lv-CD4scFv grafts, indicating that sensitisation may have been delayed but was not prevented.Australian National Health & Medical Research Council and the Ophthalmic Research Institute of Australia

Adherence to anti-retroviral therapy among HIV patients in Bangalore, India

<p>Abstract</p> <p>Introduction</p> <p><it>Human Immunodeficiency Virus </it>(HIV) has an estimated prevalence of 0.9% in India (5.2 million). Anti-retroviral drugs (ARV) are the treatments of choice and non-adherence is an important factor in treatment failure and development of resistance, as well as being a powerful predictor of survival. This study assesses adherence to ARV in HIV positive patients in Bangalore, India, a country where only 10% of those who need therapy are receiving it.</p> <p>Methods</p> <p>A cross-sectional anonymous questionnaire survey of 60 HIV antibody positive patients was carried out with patients attending HIV outpatient services at two centres: The Chest and Maternity Centre, Rajajinagar, and Wockhardt Hospital and Heart Institute, Bangalore. Consent was obtained. Translation was done by a translator and doctors where required. Data was analysed using SPSS statistical analysis.</p> <p>Results</p> <p>A response rate of 88% (53/60) was achieved. The mean patient age was 39.98 years, with 50% aged 30–40, and 73.6% of participants being male. Mean family size was 4.8 (1–13). 21% lived less than 50 kms and 21% greater than 400 kms from clinic.</p> <p>60% reported they were fully adherent. Adherence was statistically significantly linked to regular follow-up attendance (70.5%, p = 0.002). No other results were statistically significant but trends were found. "100% adherence" trends were seen in older patients, male gender, those from larger families, those who had a previous AIDS defining illness, those taking fewer tablets, and without food restrictions. Commonest side-effects causing non-adherence were metabolic reasons (66%) and GI symptoms (50%). No trends were seen for education level, family income, distance travelled to clinic, time since diagnosis, or time on ART.</p> <p>Conclusion</p> <p>Regular attendance for follow up was statistically significant for 100% lifetime adherence. Positive trends were seen in those in larger families, older, those who had AIDS defining illness, simple regimes, and without side-effects. Education, income, distance travelled and length of time diagnosed or treated had no effect on adherence.</p

The impact of early-years provision in Children's Centres (EPICC) on child cognitive and socio-emotional development: study protocol for a randomised controlled trial.

BACKGROUND: There are marked disparities between pre-school children in key skills affecting school readiness, disparities that commonly persist and influence children's later academic achievements, employment, and adjustment. Much of this disparity is linked to socio-economic disadvantage and its impact on the home learning environment. Children's Centres are an ideal context in which to implement and evaluate programmes to address this problem. They principally serve the 30% worst areas on the Indices of Deprivation Affecting Children, providing for families from the antenatal period up to age 5 years, aiming to promote parenting skills and provide care for children. METHODS: We are conducting a randomised controlled trial, based in Children Centres, to evaluate a parenting intervention for caregivers of children between 28 and 45 months of age. The intervention provides training to parents in dialogic book-sharing. The training is run by a facilitator who sees parents in small groups, on a weekly basis over 7 weeks. The study is a cluster randomised controlled trial. Twelve of the Children's Centres in the town of Reading in the UK have been randomly assigned to an index or control condition. The primary outcome is child cognition (language, attention, and executive function); and secondary outcomes are child social development, behaviour problems, and emotion regulation, parenting during book-sharing and problem solving and parental child behaviour management strategies. Data are collected at baseline, post-intervention and 4-6 months post-intervention. DISCUSSION: The Impact of Early-years Provision in Children's Centres trial (EPICC) aims to evaluate the impact of an early parenting intervention on several key risk factors for compromised child development, including aspects of parenting and child cognition, social development, behaviour problems and emotion regulation. The study is being carried out in Children's Centres, which largely serve the most disadvantaged families in the UK. Since the intervention is brief and, with modest levels of training, readily deliverable within Children's Centres and similar early childcare provision centres, demonstration that it is of benefit to child cognition, socio-emotional development and behaviour would be important. TRIAL REGISTRATION: ISRCTN Registry, ISRCTN28513611 . Registered on 28 March 2017. This is version 1 of the protocol for the EPICC trial

Patients with presumed tuberculosis in sub-Saharan Africa that are not diagnosed with tuberculosis: a systematic review and meta-analysis.

BACKGROUND: Many patients in sub-Saharan Africa whom a diagnosis of tuberculosis is considered are subsequently not diagnosed with tuberculosis. The proportion of patients this represents, and their alternative diagnoses, have not previously been systematically reviewed. METHODS: We searched four databases from inception to 27 April 2020, without language restrictions. We included all adult pulmonary tuberculosis diagnostic studies from sub-Saharan Africa, excluding case series and inpatient studies. We extracted the proportion of patients with presumed tuberculosis subsequently not diagnosed with tuberculosis and any alternative diagnoses received. We conducted a random effects meta-analysis to obtain pooled estimates stratified by passive and active case finding. RESULTS: Our search identified 1799 studies, of which 18 studies (2002-2019) with 14 527 participants from 10 African countries were included. The proportion of patients with presumed tuberculosis subsequently not diagnosed with tuberculosis was 48.5% (95% CI 39.0 to 58.0) in passive and 92.8% (95% CI 85.0 to 96.7) in active case-finding studies. This proportion increased with declining numbers of clinically diagnosed tuberculosis cases. A history of tuberculosis was documented in 55% of studies, with just five out of 18 reporting any alternative diagnoses. DISCUSSION: Nearly half of all patients with presumed tuberculosis in sub-Saharan Africa do not have a final diagnosis of active tuberculosis. This proportion may be higher when active case-finding strategies are used. Little is known about the healthcare needs of these patients. Research is required to better characterise these patient populations and plan health system solutions that meet their needs. PROSPERO REGISTRATION NUMBER: CRD42018100004

Road2CPS priorities and recommendations for research and innovation in cyber-physical systems

This document summarises the findings of the Road2CPS project, co-financed by the European Commission under the H2020 Research and Innovation Programme, to develop a roadmap and recommendations for strategic action required for future deployment of Cyber-Physical Systems (CPS). The term Cyber-Physical System describes hardware-software systems, which tightly couple the physical world and the virtual world. They are established from networked embedded systems that are connected with the outside world through sensors and actuators and have the capability to collaborate, adapt, and evolve. In the ARTEMIS Strategic Research Agenda 2016, CPS are described as ‘Embedded Intelligent ICT Systems’ that make products smarter, more interconnected, interdependent, collaborative, and autonomous. In the future world of CPS, a huge number of devices connected to the physical world will be able to exchange data with each other, access web services, and interact with people. Moreover, information systems will sense, monitor and even control the physical world via Cyber-Physical Systems and the Internet of Things (HiPEAC Vision 2015). Cyber-Physical Systems find their application in many highly relevant areas to our society: multi-modal transport, health, smart factories, smart grids and smart cities amongst others. The deployment of Cyber-Physical Systems (CPS) is expected to increase substantially over the next decades, holding great potential for novel applications and innovative product development. Digital technologies have already pervaded day-to-day life massively, affecting all kinds of interactions between humans and their environment. However, the inherent complexity of CPSs, as well as the need to meet optimised performance and comply with essential requirements like safety, privacy, security, raises many questions that are currently being explored by the research community. Road2CPS aims at accelerating uptake and implementation of these efforts. The Road2CPS project identifying and analysing the relevant technology fields and related research priorities to fuel the development of trustworthy CPS, as well as the specific technologies, needs and barriers for a successful implementation in different application domains and to derive recommendations for strategic action. The document at hand was established through an interactive, community-based approach, involving over 300 experts from academia, industry and policy making through a series of workshops and consultations. Visions and priorities of recently produced roadmaps in the area of CPS, IoT (Internet of Things), SoS (System-of-Systems) and FoF (Factories of the Future) were discussed, complemented by sharing views and perspectives on CPS implementation in application domains, evolving multi-sided eco-systems as well as business and policy related barriers, enablers and success factors. From the workshops and accompanying activities recommendations for future research and innovation activities were derived and topics and timelines for their implementation proposed. Amongst the technological topics, and related future research priorities ‘integration, interoperability, standards’ ranged highest in all workshops. The topic is connected to digital platforms and reference architectures, which have already become a key priority theme for the EC and their Digitisation Strategy as well as the work on the right standards to help successful implementation of CPSs. Other themes of very high technology/research relevance revealed to be ‘modelling and simulation’, ‘safety and dependability’, ‘security and privacy’, ‘big data and real-time analysis’, ‘ubiquitous autonomy and forecasting’ as well as ‘HMI/human machine awareness’. Next to this, themes emerged including ‘decision making and support’, ‘CPS engineering (requirements, design)’, ‘CPS life-cycle management’, ‘System-of-Systems’, ‘distributed management’, ‘cognitive CPS’, ‘emergence, complexity, adaptability and flexibility’ and work on the foundations of CPS and ‘cross-disciplinary research/CPS Science’