609 research outputs found
Penrose Limits of Orbifolds and Orientifolds
We study the Penrose limit of various AdS_p X S^q orbifolds. The limiting
spaces are waves with parallel rays and singular wave fronts. In particular, we
consider the orbifolds AdS_3 X S^3/\Gamma, AdS_5 X S^5/\Gamma and AdS_{4,7} X
S^{7,4}/\Gamma where \Gamma acts on the sphere and/or the AdS factor. In the
pp-wave limit, the wave fronts are the orbifolds C^2/\Gamma, C^4/\Gamma and R
XC^4/\Gamma, respectively. When desingularization is possible, we get
asymptotically locally pp-wave backgrounds (ALpp). The Penrose limit of
orientifolds are also discussed. In the AdS_5 X RP^5 case, the limiting
singularity can be resolved by an Eguchi-Hanson gravitational instanton. The
pp-wave limit of D3-branes near singularities in F-theory is also presented.
Finally, we give the embedding of D-dimensional pp-waves in flat M^{2,D} space.Comment: 20 pages, references adde
Loop operators and S-duality from curves on Riemann surfaces
We study Wilson-'t Hooft loop operators in a class of N=2 superconformal
field theories recently introduced by Gaiotto. In the case that the gauge group
is a product of SU(2) groups, we classify all possible loop operators in terms
of their electric and magnetic charges subject to the Dirac quantization
condition. We then show that this precisely matches Dehn's classification of
homotopy classes of non-self-intersecting curves on an associated Riemann
surface--the same surface which characterizes the gauge theory. Our analysis
provides an explicit prediction for the action of S-duality on loop operators
in these theories which we check against the known duality transformation in
several examples.Comment: 41 page
N=1* in 5 dimensions: Dijkgraaf-Vafa meets Polchinski-Strassler
One of the powerful techniques to analyze the 5 dimensional Super Yang Mills
theory with a massive hypermultiplet (N=1*) is provided by the AdS/CFT
correspondence. It predicts that, for certain special values of the
hypermultiplet mass, this theory develops nonperturbative branches of the
moduli space as well as new light degrees of freedom.
We use the higher dimensional generalization of the matrix model/gauge theory
correspondence and recover all the prediction of the supergravity analysis. We
construct the map between the four dimensional holomorphic superpotential and
the five dimensional action and explicitly show that the superpotential is flat
along the nonperturbative branches. This is the first instance in which the
Dijkgraaf-Vafa method is used to analyze intrinsically higher dimensional
phenomena.Comment: 28 pages, Late
Topological Field Theory and Rational Curves
We analyze the superstring propagating on a Calabi-Yau threefold. This theory
naturally leads to the consideration of Witten's topological non-linear
sigma-model and the structure of rational curves on the Calabi-Yau manifold. We
study in detail the case of the world-sheet of the string being mapped to a
multiple cover of an isolated rational curve and we show that a natural
compactification of the moduli space of such a multiple cover leads to a
formula in agreement with a conjecture by Candelas, de la Ossa, Green and
Parkes.Comment: 20 page
Pediatric patients with multi-organ dysfunction syndrome receiving continuous renal replacement therapy
Pediatric patients with multi-organ dysfunction syndrome receiving continuous renal replacement therapy.BackgroundCritical illness leading to multi-organ dysfunction syndrome (MODS) and associated acute renal failure (ARF) is less common in children compared to adult patients. As a result, many issues plague the pediatric ARF outcome literature, including a relative lack of prospective study, a lack of modality stratification in subject populations and inconsistent controls for patient illness severity in outcome analysis.MethodsWe now report data from the first multicenter study to assess the outcome of pediatric patients with MODS receiving continuous renal replacement therapy (CRRT). One hundred twenty of 157 Registry patients (63 male/57 female) experienced MODS during their course.ResultsOne hundred sixteen patients had complete data available for analysis. The most common causes leading to CRRT were sepsis (N = 47; 39.2%) and cardiogenic shock (N = 24; 20%). Overall survival was 51.7%. Pediatric Risk of Mortality (PRISM 2) score, central venous pressure (CVP), and% fluid overload (%FO) at CRRT initiation were significantly lower for survivors versus nonsurvivors. Multivariate analysis controlling for severity of illness using PRISM 2 at CRRT initiation revealed that%FO was still significantly lower for survivors versus nonsurvivors (P < 0.05) even for patients receiving both mechanical ventilation and vasoactive pressors. We speculate that increased fluid administration from PICU admission to CRRT initiation is an independent risk factor for mortality in pediatric patients with MODS receiving CRRT.ConclusionWe suggest that after initial resuscitative efforts, an increased emphasis should be placed on early initiation of CRRT and inotropic agent use over fluid administration to maintain acceptable blood pressure
"Dark energy" in the Local Void
The unexpected discovery of the accelerated cosmic expansion in 1998 has
filled the Universe with the embarrassing presence of an unidentified "dark
energy", or cosmological constant, devoid of any physical meaning. While this
standard cosmology seems to work well at the global level, improved knowledge
of the kinematics and other properties of our extragalactic neighborhood
indicates the need for a better theory. We investigate whether the recently
suggested repulsive-gravity scenario can account for some of the features that
are unexplained by the standard model. Through simple dynamical considerations,
we find that the Local Void could host an amount of antimatter
() roughly equivalent to the mass of a typical
supercluster, thus restoring the matter-antimatter symmetry. The antigravity
field produced by this "dark repulsor" can explain the anomalous motion of the
Local Sheet away from the Local Void, as well as several other properties of
nearby galaxies that seem to require void evacuation and structure formation
much faster than expected from the standard model. At the global cosmological
level, gravitational repulsion from antimatter hidden in voids can provide more
than enough potential energy to drive both the cosmic expansion and its
acceleration, with no need for an initial "explosion" and dark energy.
Moreover, the discrete distribution of these dark repulsors, in contrast to the
uniformly permeating dark energy, can also explain dark flows and other
recently observed excessive inhomogeneities and anisotropies of the Universe.Comment: 6 pages, accepted as a Letter to the Editor by Astrophysics and Space
Scienc
RG flows from Spin(7), CY 4-fold and HK manifolds to AdS, Penrose limits and pp waves
We obtain explicit realizations of holographic renormalization group (RG)
flows from M-theory, from E^{2,1} \times Spin(7) at UV to AdS_4 \times
\tilde{S^7} (squashed S^7) at IR, from E^{2,1} \times CY4 at UV to AdS_4 \times
Q^{1,1,1} at IR, and from E^{2,1} \times HK (hyperKahler) at UV to AdS_4 \times
N^{0,1,0} at IR. The dual type IIA string theory configurations correspond to
D2-D6 brane systems where D6 branes wrap supersymmetric four-cycles. We also
study the Penrose limits and obtain the pp-wave backgrounds for the above
configurations. Besides, we study some examples of non-supersymmetric and
supersymmetric flows in five-dimensional gauge theories.Comment: 42 pages, 6 eps figures, typos and misprints correcte
Mycoplasma genitalium: an efficient strategy to generate genetic variation from a minimal genome
Mycoplasma genitalium, a human pathogen associated with sexually transmitted diseases, is unique in that it has smallest genome of any known free-living organism. The goal of this study was to investigate if and how M. genitalium uses a minimal genome to generate genetic variations. We analysed the sequence variability of the third gene (MG192 or mgpC) of the M. genitalium MgPa adhesion operon, demonstrated that the MG192 gene is highly variable among and within M. genitalium strains in vitro and in vivo, and identified MG192 sequence shifts in the course of in vitro passage of the G37 type strain and in sequential specimens from an M. genitalium-infected patient. In order to establish the origin of the MG192 variants, we examined nine genomic loci containing partial copies of the MgPa operon, known as MgPar sequences. Our analysis suggests that the MG192 sequence variation is achieved by recombination between the MG192 expression site and MgPar sequences via gene cross-over and, possibly, also by gene conversion. It appears plausible that M. genitalium has the ability to generate unlimited variants from its minimized genome, which presumably allows the organism to adapt to diverse environments and/or to evade host defences by antigenic variation
A Measurement of the Decay Asymmetry Parameters in \Xi_{c}^{0}\to \X^{-}\pi^{+}
Using the CLEO II detector at the Cornell Electron Storage Ring we have
measured the decay asymmetry parameter in the decay . We find , using the world average value of
we obtain . The physically allowed range of a decay
asymmetry parameter is . Our result prefers a negative value:
is at the 90% CL. The central value occupies the
middle of the theoretically expected range but is not yet precise enough to
choose between models.Comment: 10 pages postscript, also available through
http://w4.lns.cornell.edu/public/CLN
Production and Decay of D_1(2420)^0 and D_2^*(2460)^0
We have investigated and final states and
observed the two established charmed mesons, the with mass
MeV/c and width MeV/c and
the with mass MeV/c and width
MeV/c. Properties of these final states, including
their decay angular distributions and spin-parity assignments, have been
studied. We identify these two mesons as the doublet predicted
by HQET. We also obtain constraints on {\footnotesize } as a function of the cosine of the relative phase of the two
amplitudes in the decay.Comment: 15 pages in REVTEX format. hardcopies with figures can be obtained by
sending mail to: [email protected]
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