72 research outputs found

    Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic

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    This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic

    Final results from the PERUSE study of first-line pertuzumab plus trastuzumab plus a taxane for HER2-positive locally recurrent or metastatic breast cancer, with a multivariable approach to guide prognostication

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    Gynecological Trauma and Emergencies

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    The current active duty population consists of 14% women, many of whom are subject to the same risks of combat injury as their male colleagues. This chapter deals with OB/GYN emergencies that may present to a deployed medical treatment facility, particularly in military operations other than war

    Gynecological Trauma and Emergencies

    No full text
    The current active duty population consists of 14% women, many of whom are subject to the same risks of combat injury as their male colleagues. This chapter deals with OB/GYN emergencies that may present to a deployed medical treatment facility, particularly in military operations other than war

    Hemorrhagic Shock after Neonatal Circumcision: Severe Congenital Factor XIII Deficiency

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    A Caucasian male infant born full term via normal spontaneous vaginal delivery was given vitamin K after birth, circumcised on day of life (DOL) 1, and discharged from the nursery on DOL 2. At the time of circumcision, oozing from the surgical site was noted and initially resolved with silver nitrate. Over the next two days, he presented to local emergency rooms multiple times for recurrent bleeding, eventually developing hemorrhagic shock resulting in admission to the neonatal intensive care unit. After extensive work up, he was ultimately diagnosed with severe congenital factor XIII deficiency. Congenital factor XIII deficiency is a rare bleeding disorder characterized by normal prothrombin time (PT) and activated partial thromboplastin time (aPTT) coagulation labs on routine screening, and has a high risk of complications, such as spontaneous intracranial hemorrhage. Although uncommon, when caring for a child with bleeding, physicians must have a high index of suspicion to make this diagnosis in order to initiate proper treatment and start prophylaxis given the risk of morbidity and mortality in untreated patients
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