Dimensions of Individuals\u27 Judgements about Sexual Attraction, Romantic Attachment, and Sexual Orientation

Despite 150 years of scientific interest in sexual orientation, contemporary investigators grapple with a number of serious difficulties. A precise, unified definition of sexual orientation appropriate for scientific use continues to elude researchers, most likely because there is still no single coherent theory of sexual orientation. This lack impedes research into the measurement of sexual orientation. Existing measurements of sexual orientation rely on partial or incompletely empirical research. The present study identified promising avenues for development of credible definitions, theories, and measurements of sexual orientation: (a) mate-selection tasks; (b) the idea that bisexually-identified individuals place a lower priority on partner gender in mate-selection decisions; (c) using “gender diagnosticity”—i.e., measures that differentiate between men and women, using an empirical criterion—to investigate the connections between gender-role orientation, sexual orientation, and mate selection; (d) distinguishing between sexual desire and pair bonding; (e) a cross-category theory of sexual orientation identity. The present study was conducted via an Internet survey. Participants were 726 participants with varying gender and sexual orientation identities. A large number of participants espoused nontraditional gender and sexual orientation identities. Results indicated strong support for distinguishing between sexual desire and pair bonding, in that different decision rules for mate selection obtained in each, and for understanding bisexuality as involving lower prioritization of partner gender. The utility of mate-selection tasks was also supported. The use of gender diagnosticity was partly supported, in that a relationship between adult gender typicality and sexual orientation was found, but further investigation is needed to determine appropriate measures as vehicles for this approach. Conceptualizations of sexual orientation were observed to vary with gender and sexual orientation identity categories, though there was also substantial agreement across categories. The cross-category theory of sexual orientation was partially supported in that heterosexually-identified participants who endorsed some same-sex sexuality appeared to be actively exploring their sexual orientation identity. The results highlighted the fractal and dynamic complexity and interrelationship of gender and sexual orientation, and the need to understand nontraditional gender and sexual orientation identities. Advisor: Debra A. Hop

Correlates of Same-Sex Attractions and Behaviors among Self-Identified Heterosexual University Students

Few studies have focused on intragroup variations in sexual orientation and fewer on self-identified heterosexuals with same-sex attractions, fantasies, and/or behaviors. Self-identified heterosexual students at a large public midwestern university (N = 263) completed measures of sexuality and gender, attitudes toward lesbian, gay, and bisexual (LGB) people, religious and political beliefs, emotional well-being, and demographics. The sample included 82 individuals (31%; labeled “H+”) who endorsed same-sex attraction, fantasy, and/or behavior and 181 (69%; labeled “H”) who did not. Women were more likely to be categorized as H+ than men. H+ participants had more positive attitudes toward lesbians and gay and bisexual men and reported more support for LGB-positive public policies than did H participants. H+ participants reported less literalistic beliefs about religious scripture than did H participants. H and H+ groups did not differ significantly on measures of emotional well-being. Results were discussed in the context of recent literature arguing for a more nuanced and gender-differentiated approach toward assessing sexual orientation, as well as literature on the flexibility of sexual orientation and on heterosexual identity development

Depression and anxiety and their association with healthcare utilization in pediatric lupus and mixed connective tissue disease patients: a cross-sectional study

Background Depression and anxiety adversely affects outcomes in systemic lupus erythematosus (SLE) and healthcare utilization is high for pediatric SLE. We aimed to characterize the prevalence of depression and anxiety in pediatric SLE, and their association with healthcare utilization. Methods We conducted a cross-sectional analysis of pediatric SLE and mixed connective tissue disease (MCTD) subjects and healthy controls aged 8 years and above. We used the Patient Health Questionnaire 9 (PHQ-9) and the Screen for Childhood Anxiety Related Disorders (SCARED) to identify depression, suicidal ideation and anxiety symptoms, respectively. We compared symptom prevalence in SLE/MCTD and healthy subjects using logistic regression. For SLE/MCTD subjects, we calculated the rate of annual outpatient visits [rheumatology/nephrology, primary care provider (PCP) and emergency department], hospitalizations and rheumatology/nephrology telephone consultations in the preceding year. We compared these outcomes in those with and without depression and anxiety using negative binomial regression. Results We identified depression symptoms in 10 (20%) SLE/MCTD and 4 (8%) healthy subjects, representing a trend towards increased prevalence in unadjusted analysis (OR = 2.9, 95% CI 0.8-9.9, p = 0.09). Adjusted analysis did not show a significant difference; however, non-white race was a statistically significant independent risk factor for depression symptoms compared to white race (OR = 5.4, 95% CI 1.1-27.2, p = 0.04). We identified anxiety symptoms in 11 (22%) SLE/MCTD and 13 (26%) healthy subjects, which was not statistically different. Suicidal ideation was present in 7 (14%) SLE/MCTD and 2 (4%) healthy subjects, which was a statistically significant difference (OR = 5.4, 95% CI 1.02-28.3, p = 0.047). Of the 34% of SLE/MCTD subjects with any symptoms, only 24% had previous mental health care. Those with depression symptoms had a statistically significant lower rate of visits to the PCP (IRR = 0.38, 95% CI 0.19-0.76, p \u3c 0.001). Anxiety symptoms were not associated with the healthcare utilization outcomes. Conclusions Depression and anxiety symptoms were prevalent, and suicidal ideation significantly more common in SLE/MCTD than in healthy subjects. Non-white race was an independent risk factor for depression. Despite prevalent symptoms, there were poor rates of prior mental health treatment, and less frequent PCP visits among those with depression symptoms. Further investigation of barriers to mental health care and interventional strategies for symptomatic youth with SLE/MCTD is needed

The causal effect of testosterone on men’s competitive behavior is moderated by basal cortisol and cues to an opponent’s status: Evidence for a context-dependent dual hormone hypothesis

Testosterone has been theorized to direct status-seeking behaviors, including competitive behavior. However, most human studies to date have adopted correlational designs, and findings across studies are inconsistent. This experiment (n = 115) pharmacologically manipulated men’s testosterone levels prior to a mixed-gender math competition and examined basal cortisol (a hormone implicated in stress and social avoidance) and context cues related to an opponent’s perceived status (an opponent’s gender or a win/loss in a prior competition) as factors that may moderate testosterone’s impact on competitive behavior. We test and find support for the hypothesis that testosterone given to low-cortisol men evokes status-seeking behavior, whereas testosterone given to high-cortisol men evokes status-loss avoidance. In the initial rounds of competition, testosterone’s influence on competitive decisions depended on basal cortisol and opponent gender. After providing opponent-specific win-lose feedback, testosterone’s influence on decisions to re-enter competitions depended on basal cortisol and this objective cue to status, not gender. Compared to placebo, men given exogenous testosterone who were low in basal cortisol showed an increased tendency to compete against male and high-status opponents relative to female and low-status opponents (status-seeking). Men given exogenous testosterone who were high in basal cortisol showed the opposite pattern - an increased tendency to compete against female and low-status opponents relative to male and high-status opponents (status-loss avoidance). These results provide support for a context-dependent dual hormone hypothesis: Testosterone flexibly directs men’s competitive behavior contingent on basal cortisol levels and cues that signal an opponent’s status

The causal effect of testosterone on men’s competitive behavior is moderated by basal cortisol and cues to an opponent’s status: Evidence for a context-dependent dual-hormone hypothesis

Testosterone has been theorized to direct status-seeking behaviors, including competitive behavior. However, most human studies to date have adopted correlational designs, and findings across studies are inconsistent. This experiment (n = 115) pharmacologically manipulated men's testosterone levels prior to a mixed-gender math competition and examined basal cortisol (a hormone implicated in stress and social avoidance) and context cues related to an opponent's perceived status (an opponent's gender or a win/loss in a prior competition) as factors that may moderate testosterone's impact on competitive behavior. We test and find support for the hypothesis that testosterone given to low-cortisol men evokes status-seeking behavior, whereas testosterone given to high-cortisol men evokes status-loss avoidance. In the initial rounds of competition, testosterone's influence on competitive decisions depended on basal cortisol and opponent gender. After providing opponent-specific win-lose feedback, testosterone's influence on decisions to reenter competitions depended on basal cortisol and this objective cue to status, not gender. Compared to placebo, men given exogenous testosterone who were low in basal cortisol showed an increased tendency to compete against male and high-status opponents relative to female and low-status opponents (status-seeking). Men given exogenous testosterone who were high in basal cortisol showed the opposite pattern-an increased tendency to compete against female and low-status opponents relative to male and high-status opponents (status-loss avoidance). These results provide support for a context-dependent dual-hormone hypothesis: Testosterone flexibly directs men's competitive behavior contingent on basal cortisol levels and cues that signal an opponent's status. (PsycInfo Database Record (c) 2022 APA, all rights reserved)

Pediatric SLE hospitalization Personal non-commercial use only

ABSTRACT. Objective. In the setting of recent healthcare advances and emphasis on reduced spending, we aimed to characterize US trends in inpatient healthcare use and mortality for pediatric systemic lupus erythematosus (SLE). Methods. We performed a retrospective, serial, cross-sectional analysis of the national Kids' Inpatient Database (for 2000, 2003, 2006, and 2009). We identified patients with SLE aged 2 to 21 years using an International Classification of Diseases, 9th revision (ICD-9) code of 710.0 listed as a discharge diagnosis. Using sampling weights, we estimated trends in hospitalization, inpatient mortality, procedure rates, and length of stay (LOS). We analyzed patient and hospital-specific risk factors for mortality and LOS, and compared those outcomes to those without SLE. Results. We identified 26,903 estimated pediatric SLE hospitalizations. The hospitalization rate of 8.6 (95% CI 7.6-9.6) per 100,000 population and mean LOS of 5.9 days (95% CI 5.6-6.2) were stable over time. We found a significant downward trend in mortality, decreasing from 1% to 0.6% (p = 0.04), which paralleled a less pronounced trend for those without SLE. The rate of dialysis, blood transfusions, and vascular catheterization procedures increased. Patients with SLE nephritis and non-white race were at risk for increased healthcare use and death. Conclusion. Pediatric SLE hospitalization rate and LOS remained stable, but inpatient mortality decreased as the rate of common therapeutic procedures increased. More research is needed to understand the drivers of these relationships

Exogenous testosterone enhances cortisol and affective responses to social evaluative stress in dominant men

Stress often precedes the onset of mental health disorders and is linked to negative impacts on physical health as well. Prior research indicates that testosterone levels are related to reduced stress reactivity in some cases but correlate with increased stress responses in other cases. To resolve these inconsistencies, we tested the causal influence of testosterone on stress reactivity to a social-evaluative stressor. Further, prior work has failed to consider status-relevant individual differences such as trait dominance that may modulate the influence of testosterone on responses to stressors. Participants (n = 120 males) were randomly assigned to receive exogenous testosterone or placebo (n = 60 testosterone treatment group) via topical gel prior to a well-validated social-evaluative stressor. Compared to placebo, testosterone significantly increased cortisol and negative affect in response to the stressor, especially for men high in trait dominance (95% confidence intervals did not contain zero). The findings suggest that the combination of high testosterone and exposure to status-relevant social stress may confer increased risk for stress-mediated disorders, particularly for individuals high in trait dominance